Medical Specialties Commons^™

The New Oral Anticoagulants For The Treatment Of Venous Thromboembolism: A New Paradigm Shift In Antithrombotic Therapy., Taki Galanis, Gina Keiffer, Geno J Merli

Department of Medicine Faculty Papers

BACKGROUND: Several novel oral anticoagulants have been studied for the prevention and treatment of venous thromboembolism (VTE) in different patient populations. Clinicians will increasingly encounter scenarios in which they must choose among these and conventional anticoagulants for the treatment of this potentially fatal condition.

OBJECTIVE: To review the results of Phase III clinical trials that investigated the novel oral anticoagulants for the treatment of deep vein thrombosis and pulmonary embolism. Potential advantages and disadvantages of these anticoagulant agents with respect to each other and conventional therapy will also be explored through a case-based approach.

METHODS: A literature search in PubMed …

Adenomyomatous Hyperplasia Of The Ampulla Of Vater Masquerading As Malignancy: A Case Series, Patrick Hickey Do, Saba Ahmad Md, Matthew Sullivan Do, Miriam L. Enriquez Md, Jeffrey Brodsky Md, Hiral Shah Md

Department of Medicine

No abstract provided.

Robotic Sublobar Resection For The Surgical Management Of Isolated Pulmonary Nodules, Michael F. Szwerc Md, Victor Reis Md, Kyle M. Langston Pa-C, Alec Talsania Md, Alex Werner

Department of Surgery

No abstract provided.

Ecmo For Adults Ards, James Wu

James K Wu MD

No abstract provided.

National Trauma Institute Prospective Evaluation Of The Ventilator Bundle In Trauma Patients: Does It Really Work?, Martin A. Croce Md, Karen J. Brasel Md, Mph, Raul Coimbra Md, Phd, Charles A. Adams Jr, Md, Preston R. Miller Md, Michael D. Pasquale Md, Facs, Fccm, Chanchai S. Mcdonald Phd, Somchan Vuthipadadon Phd, Timothy C. Fabian Md, Elizabeth A. Tolley Phd

Michael D Pasquale MD, FACS, FCCM

BACKGROUND: Since its introduction by the Institute for Healthcare Improvement, the ventilator bundle (VB) has been credited with a reduction in ventilator-associated pneumonia (VAP). The VB consists of stress ulcer prophylaxis, deep venous thrombosis prophylaxis, head-of-bed elevation, and daily sedation vacation with weaning assessment. While there is little compelling evidence that the VB is effective, it has been widely accepted. The Centers for Medical and Medicaid Services has suggested that VAP should be a "never event" and may reduce payment to providers. To provide evidence of its efficacy, the National Trauma Institute organized a prospective multi-institutional trial to evaluate the …

Decreasing The Incidence Of Tuberculosis In Renal Transplant Patients: A Single Center Review, Heidi Dauter Msn, Fnp-Bc, Cctc, Brandi Kolokas Ccma, Lynsey S. Biondi Md, Facs

Department of Surgery

No abstract provided.

Antibiotics In Abdominal Wall Reconstruction, Joseph J. Stirparo Md, Michael D. Pasquale Md, Facs, Fccm

Michael D Pasquale MD, FACS, FCCM

No abstract provided.

Health Care Reform At Trauma Centers--Mortality, Complications, And Length Of Stay, Shahid Shafi, Sunni Barnes, David Nicewander, David Ballard, Avery Nathens, Angela Ingraham, Mark Hemmila, Sandra Goble, Melanie Neal, Michael Pasquale, John Fildes, Larry Gentilello

Michael D Pasquale MD, FACS, FCCM

No abstract provided.

Health Care Reform At Trauma Centers: Mortality, Complications, And Length Of Stay (Presentation), Shahid Shafi, Sunni Barnes, David Nicewander, David Ballard, Avery Nathens, Angela Ingraham, Mark Hemmila, John Fildes, Michael Pasquale, Larry Gentilello

Michael D Pasquale MD, FACS, FCCM

No abstract provided.

Outcomes Of Recurrent Rectal Cancer After Transanal Excision, Sachin Vaid, Christopher Buzas, John S. Park Md, Robert J. Sinnott Md

Department of Surgery

No abstract provided.

Instructional Posters And Prevention Education: Do They Really Work?, William D. Mcquilken Ba, Deanna Shisslak, Judith M. Schultz Ba, Cstr

Department of Surgery

No abstract provided.

Use Of Geocoding And Us Census Data To Assess Determinants Of Outcome In Trauma Patients, Krista M. Goodman Md, John J. Hong Md, Sherrine Eid Mph, Leslie Baga Bsn, Ccrc, Michael M. Badellino Md, Mph, Facs, Michael D. Pasquale Md, Facs

Michael D Pasquale MD, FACS, FCCM

No abstract provided.

Building A Successful Team: Trials And Triumphs, Michael Pasquale

Michael D Pasquale MD, FACS, FCCM

No abstract provided.

Impact Of Age And Anticoagulation: Need For Neurosurgical Intervention In Trauma Patients With Mild Traumatic Brain Injury, Margaret Moore, Michael Pasquale, Michael Badellino

Michael D Pasquale MD, FACS, FCCM

BACKGROUND: Of the 500,000 brain injuries in the United States annually, 80% are considered mild (mild traumatic brain injury). Unfortunately, 2% to 3% of them will subsequently deteriorate and result in severe neurologic dysfunction. Intracerebral changes in the elderly, chronic oral anticoagulation, and platelet inhibition may contribute to the development of intracranial bleeding after minor head injury. We sought to investigate the association of age and the use of anticoagulation and antiplatelet therapy with neurologic deterioration and the need for neurosurgical intervention in patients presenting with mild traumatic brain injury. METHODS: A retrospective review of all adult (>14 years) …

Impact Of The Affordable Care Act On Healthcare Organizations, Michael Pasquale

Michael D Pasquale MD, FACS, FCCM

No abstract provided.

Peer Review At Work, Michael Pasquale

Michael D Pasquale MD, FACS, FCCM

No abstract provided.

Odontoid Fractures In The Elderly: Should We Operate?, Alice Fagin, Mark Cipolle, Robert Barraco, Sherrine Eid, James Reed, P. Mark Li, Michael Pasquale

Michael D Pasquale MD, FACS, FCCM

BACKGROUND: : Treatment of odontoid fractures remains controversial. There are conflicting data in the literature with regard to timing of operative fixation (OP), as well as whether OP should be performed. Within our own institution, treatment is variable depending largely on surgeon preference. This study was undertaken in an attempt to develop management consensus by examining outcomes in elderly patients with odontoid fractures and comparing OP to a nonoperative (non-OP) approach.

METHODS: : The trauma registry of our level I trauma center was queried for elderly (age > or = 60) patients with odontoid fractures from January 2000 to May 2006. …

Update In Surgery: Navigating Difficult Waters, Michael Pasquale

Michael D Pasquale MD, FACS, FCCM

No abstract provided.

Antibiotic Selection For Management Of The Infected Abdominal Wound, Michael Pasquale

Michael D Pasquale MD, FACS, FCCM

No abstract provided.

A Randomized, Double-Blind, Placebo-Controlled Study To Assess The Effect Of Recombinant Human Erythropoietin On Functional Outcomes In Anemic, Critically Ill, Trauma Subjects: The Long Term Trauma Outcomes Study, Fred Luchette, Michael Pasquale, Timothy Fabian, Wayne Langholff, Marsha Wolfson

Michael D Pasquale MD, FACS, FCCM

BACKGROUND: Achieving a higher hemoglobin (Hb) level might allow the anemic, critically ill, trauma patient to have an improved outcome during rehabilitation therapy. METHODS: Patients with major blunt trauma orthopedic injuries were administered epoetin alfa or placebo weekly both in hospital and for up to 12 weeks after discharge or until the Hb level was >12.0 g/dL, whichever occurred first. The 36-question Short Form Health Assessment questionnaire (SF-36) was used to evaluate physical function (PF) outcomes at baseline, at hospital discharge, and at several time points posthospital discharge. RESULTS: One hundred ninety-two patients were enrolled (epoetin alfa [n = 97], …

Abdominal Compartment Syndrome, Jayme D. Lieberman Md, Michael D. Pasquale Md, Facs, Fccm

Michael D Pasquale MD, FACS, FCCM

No abstract provided.

Trauma Systems: A Comprehensive Review Of Where We Are Today, Michael Pasquale

Michael D Pasquale MD, FACS, FCCM

No abstract provided.

Utilizing Tqip At Your Trauma Center, Michael Pasquale

Michael D Pasquale MD, FACS, FCCM

No abstract provided.

Human Acellular Dermal Matrix As A Prosthesis For Repair Of A Traumatic Diaphragm Rupture, Erik Teicher, Firas Madbak, Dale Dangleben, Michael Pasquale

Michael D Pasquale MD, FACS, FCCM

No abstract provided.

Tqip (Trauma Quality Improvement Program): Do The Data Tell The Whole Story About Outcomes, Michael Pasquale

Michael D Pasquale MD, FACS, FCCM

No abstract provided.

Hips Can Lie: Impact Of Excluding Isolated Hip Fractures On External Benchmarking Of Trauma Center Performance, David Gomez, Barbara Haas, Mark Hemmila, Michael Pasquale, Sandra Goble, Melanie Neal, N Mann, Wayne Meredith, Henry Cryer, Shahid Shafi, Avery Nathens

Michael D Pasquale MD, FACS, FCCM

BACKGROUND: Trauma centers (TCs) vary in the inclusion of patients with isolated hip fractures (IHFs) in their registries. This inconsistent case ascertainment may have significant implications on the assessment of TC performance and external benchmarking efforts. METHODS: Data were derived from the National Trauma Data Bank (2007-8.1). We included patients (aged 16 years or older) with Injury Severity Score value ≥ 9 who were admitted to Level I and II TCs. To ensure data quality, we limited the study to TC that routinely reported comorbidities and Abbreviated Injury Scale codes. IHF were defined as patients, aged 65 years or older, …

National Trauma Institute Prospective Evaluation Of The Ventilator Bundle In Trauma Patients: Does It Really Work? (Presentation), Martin Croce, Karen Brasel, Raul Coimbra, Charles Adams, Preston Miller, Michael Pasquale, Chanchai Mcdonald, Somchan Vuthipadadon, Timothy Fabian, Elizabeth Tolley

Michael D Pasquale MD, FACS, FCCM

No abstract provided.

No Suit, No Tie, No Problem: Fostering Relationships & Building Careers, Michael Pasquale

Michael D Pasquale MD, FACS, FCCM

No abstract provided.

First Results From Application Of An Absorbable Synthetic Membrane To Superficial And Deep Second Degree Burn Wounds, Sigrid A. Blome-Eberwein Md, Hamed Amani Md, Daniel D. Lozano Md, Deborah Boorse Rn, Cnp, Patrick Pagella Rn, Cnp

Department of Surgery

No abstract provided.

Leukopenia Management In Thymoglobulin Treated Renal Transplant Recipients, Lynsey S. Biondi Md, Michael J. Moritz Md, Janelle Cyprich

Department of Surgery

No abstract provided.