Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 3 of 3
Full-Text Articles in Medical Specialties
The Relationship Between Vascularity, P53 Gene Mutations And Distant Metastatic Disease In Epithelial Ovarian Carcinoma, Janna Girardi, Megan Samuelson, Anna Button, Koen De Geest, David P. Bender, Amina Ahmed, Michael Goodheart
The Relationship Between Vascularity, P53 Gene Mutations And Distant Metastatic Disease In Epithelial Ovarian Carcinoma, Janna Girardi, Megan Samuelson, Anna Button, Koen De Geest, David P. Bender, Amina Ahmed, Michael Goodheart
Michael J. Goodheart
Mutations of the p53 tumor suppressor gene are associated with large differences (>7 vessels/HPF) in Microvessel density (MVD) counts between primary and metastatic tumor sites in patients with epithelial ovarian cancer. These data are consistent with models demonstrating p53 mutation functions directly to influence angiogenesis. This information supports continued therapy and research involving angiogenesis inhibitors in patients with ovarian cancer, especially in the setting of increased differences in MVD between primary and metastatic sites.
The Relationship Between Vascularity, P53 Gene Mutations And Distant Metastatic Disease In Epithelial Ovarian Carcinoma, Janna Girardi, Megan Samuelson, Anna Button, Koen De Geest, David P. Bender, Amina Ahmed, Michael Goodheart
The Relationship Between Vascularity, P53 Gene Mutations And Distant Metastatic Disease In Epithelial Ovarian Carcinoma, Janna Girardi, Megan Samuelson, Anna Button, Koen De Geest, David P. Bender, Amina Ahmed, Michael Goodheart
Koen De Geest
Mutations of the p53 tumor suppressor gene are associated with large differences (>7 vessels/HPF) in Microvessel density (MVD) counts between primary and metastatic tumor sites in patients with epithelial ovarian cancer. These data are consistent with models demonstrating p53 mutation functions directly to influence angiogenesis. This information supports continued therapy and research involving angiogenesis inhibitors in patients with ovarian cancer, especially in the setting of increased differences in MVD between primary and metastatic sites.
The Relationship Between Vascularity, P53 Gene Mutations And Distant Metastatic Disease In Epithelial Ovarian Carcinoma, Janna Girardi, Megan Samuelson, Anna Button, Koen De Geest, David P. Bender, Amina Ahmed, Michael Goodheart
The Relationship Between Vascularity, P53 Gene Mutations And Distant Metastatic Disease In Epithelial Ovarian Carcinoma, Janna Girardi, Megan Samuelson, Anna Button, Koen De Geest, David P. Bender, Amina Ahmed, Michael Goodheart
David P Bender
Mutations of the p53 tumor suppressor gene are associated with large differences (>7 vessels/HPF) in Microvessel density (MVD) counts between primary and metastatic tumor sites in patients with epithelial ovarian cancer. These data are consistent with models demonstrating p53 mutation functions directly to influence angiogenesis. This information supports continued therapy and research involving angiogenesis inhibitors in patients with ovarian cancer, especially in the setting of increased differences in MVD between primary and metastatic sites.