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Medical Sciences

2020

Patent ductus arteriosus

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Patent Ductus Arteriosus Treatment In Preterm Neonates, Which Is The Drug Of Choice Paracetamol Vs Ibuprofen?, Reham S. Abd Al Hamid Jun 2020

Patent Ductus Arteriosus Treatment In Preterm Neonates, Which Is The Drug Of Choice Paracetamol Vs Ibuprofen?, Reham S. Abd Al Hamid

Journal of Medicine in Scientific Research

Background Patent ductus arteriosus (PDA) is one of the most prevalent problems in preterm infants. Although ibuprofen represents one of the choices for the closure of PDA, this treatment can cause severe gastrointestinal and adverse renal effects and worsen platelet function. Effective therapy for PDA had been suggested as paracetamol. Aim Our study is aiming to compare the efficacy and safety of paracetamol and ibuprofen. Patients and methods A prospective observational, single-center study was performed from December 2016 until August 2017, at ElGalaa Teaching Hospital in Cairo. In this study we included neonates with a gestational age of 28–36 weeks, …