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- 3D-printed porous implants (1)
- Cardiac Sodium MRI (1)
- Chronic Kidney Disease (1)
- Coronary vasculature (1)
- Data driven modelling. (1)
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- Diffusion tensor imaging (1)
- ECG Gating (1)
- Geometric distortion phantoms. (1)
- Glycosaminoglycan (1)
- Hemodialysis (1)
- Intensity Correction (1)
- Keywords: Computational fluid dynamics (1)
- Lumped parameter modelling (1)
- Magnetic resonance imaging (1)
- Metal artifacts (1)
- Periprosthetic joint infection (1)
- Quantitative susceptibility mapping (1)
- Surface Coil (1)
- Thoracic aortic aneurysm (1)
- Thoracic aortic dissection (1)
Articles 1 - 4 of 4
Full-Text Articles in Medical Specialties
Technical Adaptations For Cardiac Sodium Mri, Taylor L. Marcus
Technical Adaptations For Cardiac Sodium Mri, Taylor L. Marcus
Electronic Thesis and Dissertation Repository
Cardiac sodium (Na+) MRI has the potential to unveil relationships between chronic kidney disease (CKD) and cardiovascular disease (CVD). Unfortunately, this modality requires many technical adaptations before it’s possible to extract and compare image data between individuals. This study investigated whether cardiac electrocardiogram (ECG) gating could improve image quality, and whether a uniform phantom could increase signal uniformity if a surface coil is used to acquire the image. Healthy participants were imaged with a custom-built surface coil and 3.0-T MR system. Cardiac gated images presented with a decreased signal-to-noise ratio (SNR), but intensity correction significantly increased image signal …
Multi-Scale Computational Modeling Of Coronary Blood Flow: Application To Fractional Flow Reserve., Jermiah Joseph
Multi-Scale Computational Modeling Of Coronary Blood Flow: Application To Fractional Flow Reserve., Jermiah Joseph
Electronic Thesis and Dissertation Repository
Introduction. Fractional flow reserve (FFR) is presently an invasive coronary clinical index. Non-invasive CT imaging combined with computational coronary flow modelling may reduce the patient’s burden of undergoing invasive testing.
Research statement. The ability to obtain information of the hemodynamic significance of detected lesions would streamline decision making in escalation to invasive angiography.
Methods. A reduced order (lumped parameter) model of the coronary vasculature was further developed. The model was used in the assessment of the roles of structure and function on the FFR. Sophisticated methods were used to elicit numerical
solutions. Further, CT imaging (n = …
Quantitative Mri And 3d-Printing For Monitoring Periprosthetic Joint Infection, Greg Hong
Quantitative Mri And 3d-Printing For Monitoring Periprosthetic Joint Infection, Greg Hong
Electronic Thesis and Dissertation Repository
Joint replacements are becoming increasingly commonplace with over 130,000 joint arthroplasties being performed annually in Canada. Although joint replacement surgery is highly successful, implants do occasionally fail and need to be replaced via costly and difficult revision surgery. Periprosthetic joint infection (PJI) has recently become the leading reason for revision of both hip and knee replacements, which is unfortunate because PJI is difficult to diagnose and treat effectively; diagnosis is made particularly difficult by the lack of established non-invasive (imaging) means of evaluating PJI. This thesis aims to demonstrate that magnetic resonance imaging (MRI) has potential for diagnosing and monitoring …
Delineation Of Ascending Aortic Medial Degeneration Using Diffusion Tensor Imaging, Justin A. Ching-Johnson
Delineation Of Ascending Aortic Medial Degeneration Using Diffusion Tensor Imaging, Justin A. Ching-Johnson
Electronic Thesis and Dissertation Repository
Thoracic aortic aneurysms (TAAs) are a life-threatening dilation of the thoracic aorta that can lead to catastrophic dissection or rupture. In TAAs, the structure of the aortic wall is perturbed. Current imaging approaches assess lumen dimensions but lack the ability to delineate aortic wall architecture, a key determinant of aortic integrity. Diffusion tensor imaging (DTI) is an MRI modality which can reveal tissue microstructure through diffusion characteristics. In this thesis I investigated the potential for DTI to evaluate TAA architecture. A porcine model of aortic wall degeneration was developed, and DTI scans were performed on healthy and degenerated porcine ascending …