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Reproductive and Urinary Physiology Commons™
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Full-Text Articles in Reproductive and Urinary Physiology
Role Of Decorin At The Fetal-Maternal Interface, Chidambra D. Halari
Role Of Decorin At The Fetal-Maternal Interface, Chidambra D. Halari
Electronic Thesis and Dissertation Repository
The human placenta is an invasive tumor-like structure, this invasion being physiological. A subset of placental trophoblast called extra-villous trophoblast invades the uterine decidua and remodels uterine arteries into low-resistance, high-flow tubes to permit adequate flow of maternal blood to nourish the fetus. A poor extra-villous trophoblast invasion and uterine arterial remodeling can lead to fetal growth restriction and a serious pregnancy-associated maternal disease preeclampsia. Decorin, a leucine-rich proteoglycan produced by uterine decidual cells restrains multiple trophoblast functions: self-renewal and differentiation of trophoblast stem cells, migration, invasion, proliferation and endovascular differentiation. Additionally, decidual overproduction of decorin was associated with preeclampsia, …
Contraceptive Methods In The United States: The Question Of Abortive Mechanisms, Tara Ferenczy
Contraceptive Methods In The United States: The Question Of Abortive Mechanisms, Tara Ferenczy
Senior Honors Theses
This thesis reviews the many methods of contraception available in the United States. Although society’s understanding of women’s health has become a major topic, there is still a significant deficit of information regarding how the accessible methods affect women’s bodies, specifically reproductive tissue. The thesis analyzes numerous contraceptive options focusing specifically on the mechanisms of action to determine whether options have abortifacient properties so that readers may develop educated opinions regarding medical and ethical uses. Information involving strengths and limitations of each technique and the effects on both the female body and the reproductive material assist in understanding the process …