Reproductive and Urinary Physiology Commons^™

Magnesium is an essential nutrient that acts as a cofactor in numerous enzymatic reactions including energy metabolism, protein and nucleic acid biosynthesis. Its supplementation has shown to be advantageous in hypertension and treatment of angina. The intricate mechanistic aspects of excess dietary magnesium in testicular morphology and functions have been investigated, as the available information found insufficient. Adult male Wister strain rats were fed magnesium sulphate (MgSO4) with standard diet at diverse doses for one and two consecutive seminiferous cycles (13 and 26 days respectively). Significant increase in the activities of testicular Δ 5 3β - hydroxysteroid dehydrogenase and 17β …