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Benefit Of Intensity Modulated Bolus Electron Conformal Therapy For Post Mastectomy Chest Wall Irradiation, John Doiron
Benefit Of Intensity Modulated Bolus Electron Conformal Therapy For Post Mastectomy Chest Wall Irradiation, John Doiron
LSU Master's Theses
Purpose: The delivery of post-mastectomy radiotherapy (PMRT) with bolus electron conformal therapy (BECT) for patients with left-sided breast cancer can reduce second cancer complication probability (SCCP) compared to modern rotational intensity modulated x-ray (IMXT) techniques such as volumetric modulated arc therapy (VMAT) or Tomotherapy. However, rotational IMXT yields superior levels of dose homogeneity compared to BECT. This study investigates the use of intensity modulated (IM) BECT (IM-BECT) to improve dose homogeneity in the chest wall (CW) region of the PMRT planning target volume (PTV) abutted to parallel opposed IMXT tangents for the remaining PTV for a clinically-representative set of patients, …