Musculoskeletal, Neural, and Ocular Physiology Commons^™

Submicron Bioactive Glass Tubes For Bone Tissue Engineering, Jingwei Xie, Eric Blough, Chi-Hwa Wang

MIIR Faculty Research

Herein we describe a method to fabricate submicron bioactive glass tubes using of sol-gel and co-axial electrospinning techniques for applications in bone tissue engineering. Heavy mineral oil and gel solution were delivered by two independent syringe pumps during the co-axial electrospinning process. Subsequently, submicron bioactive glass tubes were obtained by removal of poly(vinyl pyrrolidone) (PVP) and heavy mineral oil via calcination at 600 °C for 5 h. Tubular structure was confirmed by scanning electron microscopy (SEM) and transmission electron microscopy (TEM) imaging. We examined the bioactivity of submicron bioactive glass tubes and fibers and evaluated their biocompatibility taking electrospun poly(ε-caprolactone) …