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Full-Text Articles in Genetic Phenomena

Polysorbate 80 Inhibition Of Pseudomonas Aeruginosa Biofilm Formation And Its Cleavage By The Secreted Lipase Lipa, C M. Toutain-Kidd, S C. Kadivar, C T. Bramante, S A. Bobin, Michael E. Zegans Oct 2009

Polysorbate 80 Inhibition Of Pseudomonas Aeruginosa Biofilm Formation And Its Cleavage By The Secreted Lipase Lipa, C M. Toutain-Kidd, S C. Kadivar, C T. Bramante, S A. Bobin, Michael E. Zegans

Dartmouth Scholarship

Surface-associated bacterial communities known as biofilms are an important source of nosocomial infections. Microorganisms such as Pseudomonas aeruginosa can colonize the abiotic surfaces of medical implants, leading to chronic infections that are difficult to eradicate. Our study demonstrates that polysorbate 80 (PS80), a surfactant commonly added to food and medicines, is able to inhibit biofilm formation by P. aeruginosa on a variety of surfaces, including contact lenses.


When Old-Order Amish Meet New Order Science: Genetic Maladies And The Amish Dilemma, Kelley Downey Mar 2009

When Old-Order Amish Meet New Order Science: Genetic Maladies And The Amish Dilemma, Kelley Downey

Undergraduate Research Conference

The Old World Amish, an Anabaptist Christian domination in the United States and Canada are know for their plain dress, avoidance of modern technology, and separation from the mainstream society.

A traditional agricultural religious group, the Old World Amish maintains isolation from the rest of the community. Financially well-off, they are homogeneous on education, occupation by gender, age at marriage, religion/ethnicity, and health care.

Although the Amish strongly discourage marriage between close cousins, the Lancaster Amish genealogy is described as mutational - inbreeding from multiple, remote connections rather than close consanguinity (first-cousin marriages).

Amish settlements have been identified with certain …