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Medical Sciences Commons

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Theses/Dissertations

2013

Cedarville University

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Full-Text Articles in Medical Sciences

An Evidence Based Recommendation For The Use Of 5% Human Albumin Vs. Normal Saline With Hypotension Secondary To Hypovolemia In Adult Post Operative Patients, Katherine Anne Marshall Aug 2013

An Evidence Based Recommendation For The Use Of 5% Human Albumin Vs. Normal Saline With Hypotension Secondary To Hypovolemia In Adult Post Operative Patients, Katherine Anne Marshall

Master of Science in Nursing Evidence-Based Practice Projects

Problem: 5% human albumin is used very frequently in the hospital setting with hypotensive post-surgical patients. There are associated risks with the use of human albumin and it has been shown that normal saline is at least as effective in treating extreme hypotension in this patient population.

Significance: Associated risks that are present with the use of human albumin may be equal to those of the risks of whole blood transfusions. In addition weight gain and fluid retention are complications associated with the use of human albumin versus the use of normal saline. Furthermore, human albumin costs $40.59 more than …