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Does Daily Intake Of Glucosamine Supplements Prevent The Need For Knee Replacements Later In Life For Adult Patients Predisposed To Osteoarthritis?, Nancy Helmy
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this selective EBM review is to determine whether or not daily intake of glucosamine supplements prevents the need for knee replacements later in life for adults predisposed to osteoarthritis.
STUDY DESIGN: Review of three English language primary randomized controlled trial studies published between 2001 and 2008
DATA SOURCES: Three double blind randomized control trials comparing glucosamine supplements to placebo were found using PubMed.
OUTCOMES MEASURED: Outcomes were measured using radiographic studies of the knees, joint space measurements, and symptoms were evaluated using Lequesne and WOMAC indexes.
RESULTS: The Reginster (2001) and Pavelka (2002) studies demonstrated no …