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Full-Text Articles in Medical Sciences
Advancing Risk Stratification In Hfpef: Unveiling The Potential Of Cardiac Fibrosis Markers For Early Diagnosis And Enhanced Patient Outcomes, Mariam Abdeen
Rowan-Virtua Research Day
Heart failure with preserved ejection fraction (HFpEF) challenges clinicians due to its diverse presentation and limitations in traditional diagnostic criteria. This study delves into the potential of cardiac fibrosis markers like galectin-3, NT-proBNP, and trimethylamine N-oxide (TMAO) to enhance diagnostic precision and patient outcomes in HFpEF. A systematic review of sixteen relevant studies revealed that these biomarkers offer promise for early detection and improved risk assessment. For instance, TMAO indicates systemic implications of HFpEF, while galectin-3 shows predictive value across heart failure types. Additionally, machine-learning models incorporating multiple biomarkers predict significant risk of adverse outcomes. Despite these advances, challenges like …
Effect Of Calcium Chloride And Isoflurane On Force Frequency Relationship In Canines, Harrison Patrizio, Lawrence Mulligan
Effect Of Calcium Chloride And Isoflurane On Force Frequency Relationship In Canines, Harrison Patrizio, Lawrence Mulligan
Rowan-Virtua Research Day
Proper calcium cycling is critical for a optimally functioning heart.
Improper calcium cycling in humans can contribute to heart failure.
Human calcium cycling is difficult to study due to the risks of damaging the patient’s cardiac tissue.
Risk of further damaging cardiac tissue is substantially increased in a heart failure patient.
Past studies focus on studying the effects of changing calcium cycling in lab rats.
Current research shows limited alternative methods in studying relationships between calcium cycling and FFR in larger mammals.
This project analyzes data to determine the response of the canine force frequency relationship to calcium chloride and …