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Medical Immunology

All NMU Master's Theses

2015

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A Cohort Study Investigating Autoantibody Levels During And After Infection With Influenza A Virus, Michelle Collins May 2015

A Cohort Study Investigating Autoantibody Levels During And After Infection With Influenza A Virus, Michelle Collins

All NMU Master's Theses

Antinuclear autoantibodies (ANAs) are present in all individuals. In those with autoimmune diseases they are routinely present in elevated levels. Although the nature and development of autoimmune diseases are not fully understood there are many hypotheses as to possible causes of an autoimmune disorder. One possible cause is viral infections. The scope of this thesis study was to examine if autoantibodies levels in individuals without autoimmune disorders increase during or after infection with influenza A virus. Blood was collected from volunteers (n=11) at time intervals of 0, 7, 42 and 63 days, respectively. Antibody levels were measured using ELISA assays …