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Full-Text Articles in Medical Humanities

A Survey Assessment Of Veterinarians To Determine The Level Of Preparedness For An Infectious Disease Outbreak, Tamara Crutchley Bushell Jan 2006

A Survey Assessment Of Veterinarians To Determine The Level Of Preparedness For An Infectious Disease Outbreak, Tamara Crutchley Bushell

All ETDs from UAB

Safeguarding animal health is of paramount importance to the US economy, public health and food safety. One of the most important causes of contamination in food products and of food-borne disease in humans is microorganisms that reside in the intestines of animals, such as Salmonella species and Escherichia coli O157:H7. A fundamental knowledge of the epidemiology of diseases, including an understanding of the agents and hosts, is a critical component of early (front-line) detection and prevention of contamination by microorganisms. Front-line detection is provided by animal handlers and personnel working with animals on a day-to-day basis, such as veterinarians. Currently …


The Influence Of Retroviral Codon Usage On The Acquisition Of The Trna Used To Prime Reverse Transcription, Matthew T. Palmer Jan 2006

The Influence Of Retroviral Codon Usage On The Acquisition Of The Trna Used To Prime Reverse Transcription, Matthew T. Palmer

All ETDs from UAB

An essential step in retrovirus replication is the conversion of the genomic-length viral RNA into a DNA copy, a reaction which is catalyzed by reverse transcriptase and primed by a host cell tRNA. The nearly continuous association of tRNA with the various components of translation, as well as the severely limited time in which a tRNA molecule spends in an uncharged state, constitute seemingly formidable barriers to the acquisition and use of host cell tRNA as primers. The mechanism by which retroviruses acquire this implausible primer are unknown. Naturally occurring isolates of most retrovirus species show a conserved use of …


Intestinal Peptides And Ethnic Differences In Insulin Secretion, Paul B. Higgins Jan 2006

Intestinal Peptides And Ethnic Differences In Insulin Secretion, Paul B. Higgins

All ETDs from UAB

African Americans (AA) exhibit greater insulin responses following either an oral or intravenous glucose challenge relative to their European American (EA) counterparts. The etiology of this difference is not fully understood nor has it been confirmed with a more physiologically relevant mixed meal. Insulin secretion is regulated by a variety of factors. Significant among these are the enteric peptides glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). The role of the incretin system in the ethnic differences in post challenge insulinemia has received little attention. Hence, the purpose of the study was two-fold. First, determine whether AA have higher fasting …