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Full-Text Articles in Medical Education
Itraconazole-Induced Torsade De Pointes In A Patient Receiving Methadone Substitution Therapy, Noorzurani Robson Associate Prof. Dr., B. Vicknasingam, S. Narayanan
Itraconazole-Induced Torsade De Pointes In A Patient Receiving Methadone Substitution Therapy, Noorzurani Robson Associate Prof. Dr., B. Vicknasingam, S. Narayanan
Associate Prof. Dr. Noorzurani Robson
Issues. Methadone, a pharmacological agent used to treat heroin dependence is relatively safe, but may cause cardiac arrhythmias in the concurrent presence of other risk factors. Approach and Key Findings. This case report highlights the risk of Torsade de Pointes, a life-threatening cardiac arrhythmia, in a heroin-dependent patient receiving methadone substitution therapy who was prescribed itraconazole for vaginal thrush. The patient presented to the accident and emergency department for chest discomfort and an episode of syncope following two doses of itraconazole (200 mg). Electrocardiogram monitoring at the accident and emergency department showed prolonged rate-corrected QT interval leading to Torsade de …
John Contracts Skin Disease At Spa, Donna M. Hughes Dr., Melanie Shapiro Esq
John Contracts Skin Disease At Spa, Donna M. Hughes Dr., Melanie Shapiro Esq
Donna M. Hughes
Pillows For Pain, Michael Lock