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Full-Text Articles in Pathological Conditions, Signs and Symptoms

Surgical Outcomes Of Hidradenitis Suppurativa Excision: Factors Impacting Wound Healing Time, Christina Huang, Scott H. Koeneman, Sherry Yang, Sami Tannour Aug 2026

Surgical Outcomes Of Hidradenitis Suppurativa Excision: Factors Impacting Wound Healing Time, Christina Huang, Scott H. Koeneman, Sherry Yang, Sami Tannour

Department of Surgery Faculty Papers

Hidradenitis suppurativa (HS) can be treated surgically to excise recurrent and recalcitrant regions of disease activity. However, surgical outcomes are highly variable depending on closure method, concomitant medical management and area of excision. In this study, we aim to characterise the healing courses from HS excision in a case series. To reduce operator variability, we opted to conduct a case series from a single surgeon. Surgeries conducted from June 2024-December 2025 by surgeon S.T. were included, and the postoperative course was followed until February 2026. Surgical details and postoperative course for 34 sites of HS across 20 patients were analysed. …


Biomechanical Effects Of Bilateral Torsion And Skeletal Fusion: A Case Study, Linnéa Forbes Apr 2026

Biomechanical Effects Of Bilateral Torsion And Skeletal Fusion: A Case Study, Linnéa Forbes

Honors Projects

As part of both a personal endeavor and an academic project, I have investigated the aetiology and treatment of seemingly idiopathic and debilitating leg pain in a patient over the past 10 years. Via collaboration with medical professionals at Cincinnati Children’s Hospital, Cincinnati Premier Physical Therapy, and Cincinnati Women’s TriHealth, I have identified sources of pain at the anatomical level. The combination of internal femoral torsion, external tibial torsion, pes planus, and bony fusions appear to be major perpetuators of the pain. An effective treatment continues to be evasive. To date, I have attempted to find answers through genetic approaches, …


Trends And Demographic Disparities In Septicemia-Associated Cardiac Arrest Mortality In The United States, 1999–2023, Muhammad Owais, Maham Mehfooz, Hamza Nazir, Preeti Advani, Roha Riaz, Khanij Arya, Javeria Nawaz, Syed Hadi Raza Rizvi, Murtaza Aslam, Usman Nazeer, Jairo Melo, Bravein Amalakuhan Apr 2026

Trends And Demographic Disparities In Septicemia-Associated Cardiac Arrest Mortality In The United States, 1999–2023, Muhammad Owais, Maham Mehfooz, Hamza Nazir, Preeti Advani, Roha Riaz, Khanij Arya, Javeria Nawaz, Syed Hadi Raza Rizvi, Murtaza Aslam, Usman Nazeer, Jairo Melo, Bravein Amalakuhan

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Pre-Operative Antiplatelet Therapy Is Associated With Increased Risk Of Periprosthetic Joint Infection Following Total Shoulder Arthroplasty, Muhammad Hamza Ilyas, Mohammad Daher, Viraj Deshpande, Adam Lindsay, Joseph A. Abboud, Hafiz F. Kassam Mar 2026

Pre-Operative Antiplatelet Therapy Is Associated With Increased Risk Of Periprosthetic Joint Infection Following Total Shoulder Arthroplasty, Muhammad Hamza Ilyas, Mohammad Daher, Viraj Deshpande, Adam Lindsay, Joseph A. Abboud, Hafiz F. Kassam

Rothman Institute Papers

Background Antiplatelet therapy is widely prescribed for the prevention and management of cardiovascular disease and for mitigation of thromboembolic risk. However, its impact on post-operative periprosthetic joint infection (PJI) following total shoulder arthroplasty (TSA) remains poorly defined.MethodsA retrospective cohort study was conducted using the TriNetX US Research Network. Propensity score matching was performed to balance demographics, body mass index, and Charlson Comorbidity Index variables. The primary outcome was the incidence of PJI at 90 days, 6 months, and 1 year. Secondary outcomes included post-operative medical and surgical complications. Comparative risk was quantified using risk ratios with 95% confidence intervals. Subgroup …


Atrial Fibrillation In Athletes: Mechanisms, Management, And Future Directions, Ibrahim Alameh, Ghina Al Fout, Michael D. Ezekowitz, Mohammed Kamareddine Mar 2026

Atrial Fibrillation In Athletes: Mechanisms, Management, And Future Directions, Ibrahim Alameh, Ghina Al Fout, Michael D. Ezekowitz, Mohammed Kamareddine

Department of Medicine Faculty Papers

BACKGROUND: High-volume endurance training may shift exercise from cardioprotective to arrhythmogenic, increasing the risk of atrial fibrillation (AF) in healthy athletes.

CASE SUMMARY: A 38-year-old marathon runner with a 15-year history of high-intensity endurance training presented with episodic palpitations and reduced athletic performance. Electrocardiogram showed paroxysmal AF; echocardiography revealed mild left atrial enlargement without structural heart disease. Symptoms worsened during the recovery phase after runs, suggesting vagally mediated AF. After unsuccessful flecainide therapy, he underwent pulmonary vein isolation. Twelve months later, he remained free of recurrent AF on Holter monitoring and successfully resumed endurance training following an 8-week recovery period. …


Pre-Operative Methicillin-Resistant Staphylococcus Aureus Colonization Increases The Risk Of 90-Day Medical And 2-Year Implant-Related Complications Following Primary Total Shoulder Arthroplasty: A Propensity-Matched Analysis, Muhammad Hamza Ilyas, Tarishi Parmar, Zina Smadi, Viraj A. Deshpande, Akin A. Adio, Joseph A. Abboud, Hafiz F. Kassam Mar 2026

Pre-Operative Methicillin-Resistant Staphylococcus Aureus Colonization Increases The Risk Of 90-Day Medical And 2-Year Implant-Related Complications Following Primary Total Shoulder Arthroplasty: A Propensity-Matched Analysis, Muhammad Hamza Ilyas, Tarishi Parmar, Zina Smadi, Viraj A. Deshpande, Akin A. Adio, Joseph A. Abboud, Hafiz F. Kassam

Rothman Institute Papers

BACKGROUND: Pre-operative methicillin-resistant Staphylococcus aureus (MRSA) colonization has been associated with increased risk of post-operative infection and medical complications in lower-extremity arthroplasty; however, its impact on outcomes following total shoulder arthroplasty (TSA) remains poorly understood. This study aims to evaluate the association between MRSA colonization and early medical as well as mid-term implant-related complications after primary TSA.

METHODS: The TriNetX US Research Network was queried to identify primary TSA patients. Propensity score matching (1:1) was performed using demographic characteristics and relevant comorbidities. Ninety-day medical complications, including readmission, emergency department utilization, venous thromboembolism, pneumonia, urinary tract infection, stroke, sepsis, respiratory failure, …


Transcatheter Aortic Valve Replacement In Systemic Sclerosis: A Case Series And Review Of Short- And Long-Term Outcomes, Chris T. Derk, Ahmadreza Badali, Esra Mehmetoglu, Anvitha Mummadisetty, Amit Syal, Konstantinos Parperis Mar 2026

Transcatheter Aortic Valve Replacement In Systemic Sclerosis: A Case Series And Review Of Short- And Long-Term Outcomes, Chris T. Derk, Ahmadreza Badali, Esra Mehmetoglu, Anvitha Mummadisetty, Amit Syal, Konstantinos Parperis

Student Papers, Posters & Projects

Objectives: A higher frequency of valvular heart disease is seen among Systemic Sclerosis (SSc) patients. Advanced aortic valve stenosis leads to significant morbidity in these patients with multiple other comorbidities. In this study, we aim to define the short- and long-term outcomes of transcatheter aortic valve replacement (TAVR) procedures in SSc patients. Methods: We undertook a retrospective chart review of all patients with SSc who underwent a TAVR procedure at our institution over a defined 11-year period. Demographics as well as short- and long-term outcomes were identified. Results: Fourteen SSc patients underwent a TAVR procedure between 2012 and 2023. They …


Diagnostic Accuracy Of Cerebral Amyloid Angiopathy Criteria In The First Pathologically Confirmed Thai Cohort: A Pilot Study, Thanapoom Taweephol, Thachamai Smitasiri, Thanakit Pongpitakmetha, Sekh Thanprasertsuk, Anand Viswanathan Feb 2026

Diagnostic Accuracy Of Cerebral Amyloid Angiopathy Criteria In The First Pathologically Confirmed Thai Cohort: A Pilot Study, Thanapoom Taweephol, Thachamai Smitasiri, Thanakit Pongpitakmetha, Sekh Thanprasertsuk, Anand Viswanathan

Chulalongkorn Medical Journal

Background: The gold standard for diagnosing cerebral amyloid angiopathy (CAA), full brain post-mortem examination, is rarely performed. Current diagnostic criteria, primarily based on clinico-radiological features, were developed from Western populations and may have limited applicability to Asian populations.

Objective: We aimed to evaluate the accuracy of current diagnostic criteria and examine the clinico-radiological characteristics of Thai CAA patients.

Methods: Brain histopathological specimens from patients with clinical symptoms of CAA who underwent neurosurgical procedures, including intracerebral hemorrhage (ICH) evacuation, between 2011 and 2021 at King Chulalongkorn Memorial Hospital, Thailand, were reviewed. Patient characteristics and clinical events for each individual were retrospectively …


Age And Sex Impact The Role Of Thrombospondin-2 And Thrombospondin-5 In Response To Hindlimb Ischemia, Irene Helenowski, Ashley Peters, Melissa Rangel, Corinne Bunn Md, Xuerong Wang, Kristopher Maier, Vivian Gahtan Feb 2026

Age And Sex Impact The Role Of Thrombospondin-2 And Thrombospondin-5 In Response To Hindlimb Ischemia, Irene Helenowski, Ashley Peters, Melissa Rangel, Corinne Bunn Md, Xuerong Wang, Kristopher Maier, Vivian Gahtan

Biostatistics Collaborative Core: Faculty Publications and Other Works

Peripheral arterial disease progression to critical limb ischemia remains a significant burden in the aged, necessitating revascularization. Therapies to enhance neovascularization, such as angiogenesis or arteriogenesis, may provide an option for patients not suitable for surgery. The thrombospondins (TSPs) are secreted matricellular glycoproteins, with TSP-1, TSP-2, and TSP-5 implicated in neovascularization. Currently, there is little data regarding the effects of TSP-2, TSP-5, sex, and aging on angiogenesis and arteriogenesis. In vitro, the effect of TSP-2 or TSP-5 on early or late passage endothelial cell (EC) tubule formation or disruption was assessed. In vivo, angiogenesis, and arteriogenesis in male and female, …


Recurrent Miller Fisher Syndrome: A Case Report, Larry Vernier, Griffin B. Gilmore, Kelsey Van Housen, Xiao C. Zhang Feb 2026

Recurrent Miller Fisher Syndrome: A Case Report, Larry Vernier, Griffin B. Gilmore, Kelsey Van Housen, Xiao C. Zhang

Department of Emergency Medicine Faculty Papers

INTRODUCTION: Guillain-Barré syndrome can manifest with progressive paralysis, requiring careful monitoring and treatment with steroids or intravenous (IV) immunoglobin. While this disease can be devastating and require intensive care unit level of care, there are few incidences of relapses.

CASE REPORT: A 67-year-old man with a past medical history of Miller Fisher syndrome variant of Guillain-Barré syndrome, with complete recovery, presented to the emergency department (ED) with ataxia, ophthalmoplegia, dysphonia, and ambulatory dysfunction. The patient noticed his neurologic symptoms after waking up, and he presented to the ED with physical examination positive for difficulty with upward gaze, mild right lower …


Improving Sepsis Order Set Utilization Through Targeted Resident Education: A Lean Six Sigma Green Belt Quality Improvement Project, Sarah Sheikh, Puneeth Shridhar, Bushra Bangash, Valerie Chukelu, Tonya Meirhofer, Arunima Jose, Zainab Shakir, Shane Jenks, Augusto Sepulveda, Trung Nguyen, Rajeev Raghavan Jan 2026

Improving Sepsis Order Set Utilization Through Targeted Resident Education: A Lean Six Sigma Green Belt Quality Improvement Project, Sarah Sheikh, Puneeth Shridhar, Bushra Bangash, Valerie Chukelu, Tonya Meirhofer, Arunima Jose, Zainab Shakir, Shane Jenks, Augusto Sepulveda, Trung Nguyen, Rajeev Raghavan

Gulf Coast Division GME Research Day 2026

No abstract provided.


Undiagnosed Placenta Accreta And Severe Postpartum Hemorrhage In A Jehovah’S Witness, Victoria Mousa Jan 2026

Undiagnosed Placenta Accreta And Severe Postpartum Hemorrhage In A Jehovah’S Witness, Victoria Mousa

Gulf Coast Division GME Research Day 2026

No abstract provided.


A Rare Case Of Invasive Group A Streptococcus Bacteremia, Extensive Streptococcal Myositis, And Septic Knee Arthritis, Cristina Lee, Morgan Seaton, Christina Mie Minami, Bailey Weidner, Dmitriy Scherbak Jan 2026

A Rare Case Of Invasive Group A Streptococcus Bacteremia, Extensive Streptococcal Myositis, And Septic Knee Arthritis, Cristina Lee, Morgan Seaton, Christina Mie Minami, Bailey Weidner, Dmitriy Scherbak

Continental and Mountain Divisions GME Resarch Day 2026

No abstract provided.


Refractory Status Epilepticus After Hair Transplant: A Case Of Lidocaine Toxicity In A Post-Craniotomy Patient, Sarai Arbus, Cheyenne Lockwood, Max Wei, Andrew Labelle Jan 2026

Refractory Status Epilepticus After Hair Transplant: A Case Of Lidocaine Toxicity In A Post-Craniotomy Patient, Sarai Arbus, Cheyenne Lockwood, Max Wei, Andrew Labelle

Continental and Mountain Divisions GME Resarch Day 2026

No abstract provided.


Septic Shock And Cardiac Arrest Secondary To Delayed Traumatic Jejunal Transection, Esra Shurbjy, Rasheed Lawal Jan 2026

Septic Shock And Cardiac Arrest Secondary To Delayed Traumatic Jejunal Transection, Esra Shurbjy, Rasheed Lawal

Gulf Coast Division GME Research Day 2026

No abstract provided.


Lemierre’S Syndrome With Copper Iud, Hemorrhagic Cyst, Septic And Hemorrhagic Shock, Kyle Distler, Alexander Sasso, Elizabeth Ryder, Suzanne Martinez, Nilmarie Guzman Jan 2026

Lemierre’S Syndrome With Copper Iud, Hemorrhagic Cyst, Septic And Hemorrhagic Shock, Kyle Distler, Alexander Sasso, Elizabeth Ryder, Suzanne Martinez, Nilmarie Guzman

South Atlantic Division GME Research Days 2026

No abstract provided.


Code Strepsis: A Multicenter Study Of The Impact Of Emergency Department Stroke Alert On Sepsis Bundle Performance In Sepsis Patients, Jason Smith, Jennifer Chapman, W Angelo Kantrales, Edward Descallar, Martin Wegman Jan 2026

Code Strepsis: A Multicenter Study Of The Impact Of Emergency Department Stroke Alert On Sepsis Bundle Performance In Sepsis Patients, Jason Smith, Jennifer Chapman, W Angelo Kantrales, Edward Descallar, Martin Wegman

South Atlantic Division GME Research Days 2026

No abstract provided.


Cholecystocolonic Fistula: Ct Diagnosis And Confirmation On Hida Scan, Adam Webb, John T. Belflower, Brian Helmly Jan 2026

Cholecystocolonic Fistula: Ct Diagnosis And Confirmation On Hida Scan, Adam Webb, John T. Belflower, Brian Helmly

South Atlantic Division GME Research Days 2026

No abstract provided.


Intracranial Mycotic Aneurysm With Subarachnoid Hemorrhage: A Rare Neurologic Presentation Of Streptococcus Constellatus Bacteremia, Matthew R. Corn, Grace Fawcett, Cooper Alden Josephs, Matthew Mcginty, Ellie Stark, Thomas Horton Jan 2026

Intracranial Mycotic Aneurysm With Subarachnoid Hemorrhage: A Rare Neurologic Presentation Of Streptococcus Constellatus Bacteremia, Matthew R. Corn, Grace Fawcett, Cooper Alden Josephs, Matthew Mcginty, Ellie Stark, Thomas Horton

South Atlantic Division GME Research Days 2026

No abstract provided.


Red Flags: Intraoperative Transfusion As A Predictor Of Anastomotic Failure, Alejandro De Leon Castro, Aj Schwartz, A Todd-Tharaday, A Collier, Ch Meyer, C Dente, Rn Smith, Jd Sciaretta, J Nguyen Jan 2026

Red Flags: Intraoperative Transfusion As A Predictor Of Anastomotic Failure, Alejandro De Leon Castro, Aj Schwartz, A Todd-Tharaday, A Collier, Ch Meyer, C Dente, Rn Smith, Jd Sciaretta, J Nguyen

South Atlantic Division GME Research Days 2026

No abstract provided.


Rapid Diagnosis Of Hemorrhagic Shock Due To Upper Gi Bleeding With Point-Of-Care Ultrasound In The Emergency Department, Tamari Ronen, Derrick Huang Jan 2026

Rapid Diagnosis Of Hemorrhagic Shock Due To Upper Gi Bleeding With Point-Of-Care Ultrasound In The Emergency Department, Tamari Ronen, Derrick Huang

Gulf Coast Division GME Research Day 2026

No abstract provided.


A Review Of Mobility And Gait Changes In Patients With Prostate Cancer: Disease Stage, Symptom, And Treatment-Related Influences, Lauren Hathorn, Abigail Schmitt Dr Jan 2026

A Review Of Mobility And Gait Changes In Patients With Prostate Cancer: Disease Stage, Symptom, And Treatment-Related Influences, Lauren Hathorn, Abigail Schmitt Dr

2026 Honors Symposium

Background: This review examines the impact of prostate cancer symptoms, progression, and treatments on patients’ gait and mobility. Prostate cancer is the leading cancer diagnosis for men in the United States, with an increase in incidents in the last decade. Prostate cancer, its progression, and its various symptoms and treatments have both physical and functional consequences that often cause changes in patients’ mobility and gait. Some studies have found gait to be a predictor of functional decline and mortality. Given that functional decline and mortality are also consequences of cancer progression and cancer treatments, gait analysis could offer a non-invasive …


The Unlikely Case Of Sporadic Immune Thrombotic Thrombocytopenic Purpura With Refractory And Seizure-Like Activity Features: Case Report, Brandon Gremmer, Alain Folefack Jan 2026

The Unlikely Case Of Sporadic Immune Thrombotic Thrombocytopenic Purpura With Refractory And Seizure-Like Activity Features: Case Report, Brandon Gremmer, Alain Folefack

North Texas GME Research Forum 2026

Introduction/Background: Thrombotic Thrombocytopenic Purpura (TTP) is a multisystem disease that can lead to multiorgan failure by disseminated mechanical destruction, microangiopathic hemolytic anemia, and thrombocytopenia. Most TTP cases are classified as acquired or hereditary; however, sporadic immune TTP with a refractory episode during the same hospital admission is not well documented in the literature. Furthermore, seizure-like activity during plasma exchange is not a common adverse effect.

Case Presentation: A 35-year-old African American female with no documented medical, surgical, or social history, changes to medications, or lifestyle changes presented with full body fatigue, fever, loss of balance, and confusion. On arrival, labs …


Effect Of Plant-Based Vs. Standard American Diet On Cardiovascular Parameters In College Students, Timothy J. Horanic Jan 2026

Effect Of Plant-Based Vs. Standard American Diet On Cardiovascular Parameters In College Students, Timothy J. Horanic

Honors Undergraduate Theses

This study examines how adherence to different dietary patterns—specifically a plant-based diet compared to the standard American diet—can influence physiological indicators tied to cardiovascular health, including heart rate variability (HRV), blood pressure (BP), and heart rate (HR). Among these markers, HRV is considered especially sensitive to autonomic nervous system (ANS) regulation and may offer earlier insight into physiological stress or dysfunction than HR or BP alone. Although nutritional habits are widely believed to impact heart health, few investigations have focused on how specific long-term diets affect autonomic and cardiovascular metrics in healthy, college-aged adults. This study aims to investigate if …


Not Your Average Taco: Persistent Hypoxemia Beyond Volume Overload, Caroline Byrd, Mohamed Faris Jan 2026

Not Your Average Taco: Persistent Hypoxemia Beyond Volume Overload, Caroline Byrd, Mohamed Faris

South Atlantic Division GME Research Days 2026

No abstract provided.


Pants On Fire: Open Surgical Repair Of A Strangulated Pantaloon Hernia With A Multi-Mesh Reconstruction, Carolyn Dudko, Saptarshi Biswas Jan 2026

Pants On Fire: Open Surgical Repair Of A Strangulated Pantaloon Hernia With A Multi-Mesh Reconstruction, Carolyn Dudko, Saptarshi Biswas

South Atlantic Division GME Research Days 2026

No abstract provided.


Right Upper Quadrant Pain With Perihepatitis, Morgan D. Homan, Jake Valentine, Edwin R. Malone Ii Jan 2026

Right Upper Quadrant Pain With Perihepatitis, Morgan D. Homan, Jake Valentine, Edwin R. Malone Ii

Gulf Coast Division GME Research Day 2026

No abstract provided.


More Than A Scratch: Capnocytophaga Bacteremia Induced Severe Sepsis With Multi-Organ Failure With Occupational Dog Exposure, Cristina Lee, Alex Craig, Dmitriy Scherbak Jan 2026

More Than A Scratch: Capnocytophaga Bacteremia Induced Severe Sepsis With Multi-Organ Failure With Occupational Dog Exposure, Cristina Lee, Alex Craig, Dmitriy Scherbak

Continental and Mountain Divisions GME Resarch Day 2026

No abstract provided.


Early Detection And Interventions For Delirium, Angel Ryals, Aneesha Shaju, Veronica Phung, Ijeoma Arubaleze Jan 2026

Early Detection And Interventions For Delirium, Angel Ryals, Aneesha Shaju, Veronica Phung, Ijeoma Arubaleze

Gulf Coast Division GME Research Day 2026

No abstract provided.


Dry Gangrene Following Av Fistula Ligation For Vascular Access-Induced Steal Syndrome: A Case Report, Marium Batool Abbas, Umema Ifran, Marelle Montanez Jan 2026

Dry Gangrene Following Av Fistula Ligation For Vascular Access-Induced Steal Syndrome: A Case Report, Marium Batool Abbas, Umema Ifran, Marelle Montanez

Gulf Coast Division GME Research Day 2026

No abstract provided.