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Immune System Diseases Commons™

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Autoimmune diseases

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Articles 1 - 30 of 35

Full-Text Articles in Immune System Diseases

Gastroparesis As Initial Feature Of Neuromyelitis Optica Spectrum Disorder, Jasmine M. Silva, Jorim J. Parmar, Shivani Gandhi, Sreevani Gudiseva Jan 2026

Gastroparesis As Initial Feature Of Neuromyelitis Optica Spectrum Disorder, Jasmine M. Silva, Jorim J. Parmar, Shivani Gandhi, Sreevani Gudiseva

North Texas GME Research Forum 2026

No abstract provided.


Autoimmune Hemolytic Anemia Following Babesiosis In An Immunocompromised Patient, Brooke Escoe, Diane Olski, Robert Sherertz, Mohamed Faris Jan 2026

Autoimmune Hemolytic Anemia Following Babesiosis In An Immunocompromised Patient, Brooke Escoe, Diane Olski, Robert Sherertz, Mohamed Faris

South Atlantic Division GME Research Days 2026

No abstract provided.


Serum Sickness–Like Reaction As The Initial Presentation Of Undiagnosed Systemic Lupus Erythematosus, Eunice Adebayo, Michael Lee Phillips, Sarah-Ellen Stephens Jan 2026

Serum Sickness–Like Reaction As The Initial Presentation Of Undiagnosed Systemic Lupus Erythematosus, Eunice Adebayo, Michael Lee Phillips, Sarah-Ellen Stephens

South Atlantic Division GME Research Days 2026

No abstract provided.


A Case Of Injury-Induced Pyoderma Gangrenosum Requiring Skin Graft, Yukiko Brewer, Nameer Ascandar, Tesnim Hamdan, Iryna Witt, Sana Khan, Robert Cropper Jan 2025

A Case Of Injury-Induced Pyoderma Gangrenosum Requiring Skin Graft, Yukiko Brewer, Nameer Ascandar, Tesnim Hamdan, Iryna Witt, Sana Khan, Robert Cropper

West Florida Division GME Research Day 2025

No abstract provided.


Covid-19 Induced Mda5-Associated Necrotizing Myositis, Sarah Steadman, Amit Sikder, Harsh R. Desai, Bradley Collins, Tiffany Baker, Julie Worthington Jan 2025

Covid-19 Induced Mda5-Associated Necrotizing Myositis, Sarah Steadman, Amit Sikder, Harsh R. Desai, Bradley Collins, Tiffany Baker, Julie Worthington

South Atlantic Division GME Research Day 2025

No abstract provided.


Co-Occurrence Of Autoimmune Hepatitis And Pheochromocytoma: A Complex Diagnostic And Treatment Challenge, Himani Patel, Gabrielle Aiello, Taylor Frazier, Sage Havrilla, Payton Williams, Meghan Rosenquist Jan 2025

Co-Occurrence Of Autoimmune Hepatitis And Pheochromocytoma: A Complex Diagnostic And Treatment Challenge, Himani Patel, Gabrielle Aiello, Taylor Frazier, Sage Havrilla, Payton Williams, Meghan Rosenquist

South Atlantic Division GME Research Day 2025

No abstract provided.


Levothyroxine And Drug-Induced Lupus Erythematosus: A Retrospective Cohort Study, Tue Nguyen, Yousef Salem, Aqsa Kanwal, Aeja Weiss Jan 2025

Levothyroxine And Drug-Induced Lupus Erythematosus: A Retrospective Cohort Study, Tue Nguyen, Yousef Salem, Aqsa Kanwal, Aeja Weiss

Gulf Coast Division GME Research Day 2025

No abstract provided.


Hydralazine Induced Anca Vasculitis, Justin Huang, Yasasvi Sabbineni, Sumanth Reddy, Hani Khair Jan 2025

Hydralazine Induced Anca Vasculitis, Justin Huang, Yasasvi Sabbineni, Sumanth Reddy, Hani Khair

North Texas Research Forum 2025

Hydralazine is a vasodilator commonly used for hypertension. Hydrazine is commonly used in patients who can not tolerate ACEs and ARBs, resistant hypertension, and during pregnancy. Hydralazine has also been implicated in ANCA-associated vasculitis and drug-induced lupus erythematosus. Vasculitis is the presence of inflammatory leukocytes in vessel walls, inflammation can cause loss of vessel integrity which can lead to bleeding and downstream tissue ischemia and necrosis. Antineutrophil cytoplasmic antibody (AΝCΑ)-associated vаsсulitiѕ (ΑΑV) is a necrotizing vаsсսlitis that does not substantially involve the deposition of immune complexes. AΑV predominantly affects small vessels and is associated with ANСΑ specific for myeloperoxidase (MPO-ΑNCΑ) …


A Rare Case Of Pulmonary Amyloidosis Causing Cystic Lung Disease In Sjogren's Syndrome, Suhas Kandimalla, Jordan Torres, Ramesh Kesavan, Siva T. Sarva Jan 2025

A Rare Case Of Pulmonary Amyloidosis Causing Cystic Lung Disease In Sjogren's Syndrome, Suhas Kandimalla, Jordan Torres, Ramesh Kesavan, Siva T. Sarva

Gulf Coast Division GME Research Day 2025

No abstract provided.


Two Is Not Always Better Than One: An Intersting Case Of Inflammatory Myositis With Dual Myositis Specific Antibodies, Neil Maithel, Rabia Mahfooz, Ali Asghar, Paul S. Bongat Jan 2025

Two Is Not Always Better Than One: An Intersting Case Of Inflammatory Myositis With Dual Myositis Specific Antibodies, Neil Maithel, Rabia Mahfooz, Ali Asghar, Paul S. Bongat

Gulf Coast Division GME Research Day 2025

No abstract provided.


Too Rash To Rule Out The Rash, Fnu Swatisikta, Chinar Singh Jan 2025

Too Rash To Rule Out The Rash, Fnu Swatisikta, Chinar Singh

East Florida Division GME Research Day 2025

No abstract provided.


Hemoptysis In A Previously Healthy Hispanic Male: A Case Of Anca Vasculitis Diagnosis, Muhammad Anzar Ullah, Angel Pacheco-Rueda, Marwa Hegagi Jan 2025

Hemoptysis In A Previously Healthy Hispanic Male: A Case Of Anca Vasculitis Diagnosis, Muhammad Anzar Ullah, Angel Pacheco-Rueda, Marwa Hegagi

West Florida Division GME Research Day 2025

No abstract provided.


When Autoimmunity Meets Pregnancy: Investigating Antiphospholipid Syndrome & Preeclampsia, Brianna Mcdonald, Madison Pearson, U Perni, Shiloh Smajstrla, Stephen Zweibach, James Baron Jan 2025

When Autoimmunity Meets Pregnancy: Investigating Antiphospholipid Syndrome & Preeclampsia, Brianna Mcdonald, Madison Pearson, U Perni, Shiloh Smajstrla, Stephen Zweibach, James Baron

West Florida Division GME Research Day 2025

No abstract provided.


A Case Study Of Necrobiosis Lipoidica And Literature Review, Kylee Arthurs, Brianna Tischner, Michael Higginbotham, Nathalie Ruiz, Juan Socas Jan 2025

A Case Study Of Necrobiosis Lipoidica And Literature Review, Kylee Arthurs, Brianna Tischner, Michael Higginbotham, Nathalie Ruiz, Juan Socas

West Florida Division GME Research Day 2025

No abstract provided.


Clotting Catastrophe: Nonbacterial Thrombotic Endocarditis (Nbte) And Ischemic Fallout, Reetom Bera, Matthew Bommarito, Dhruv Patel, Milan Patel, Rami Akel, Rami Akel, Rami Akel Jan 2025

Clotting Catastrophe: Nonbacterial Thrombotic Endocarditis (Nbte) And Ischemic Fallout, Reetom Bera, Matthew Bommarito, Dhruv Patel, Milan Patel, Rami Akel, Rami Akel, Rami Akel

West Florida Division GME Research Day 2025

No abstract provided.


Autoimmune Pancreatitis Not Otherwise Specified (Aip-Nos): The Importance Of Gastroenterology Consultation When Clinical Findings Are Concerning For Pancreatic Cancer, Cooper Alden Josephs, Daniel Mullady, Nicholas Fuerstenau, Steve Xie, Taylor Templeton-Jager Jan 2025

Autoimmune Pancreatitis Not Otherwise Specified (Aip-Nos): The Importance Of Gastroenterology Consultation When Clinical Findings Are Concerning For Pancreatic Cancer, Cooper Alden Josephs, Daniel Mullady, Nicholas Fuerstenau, Steve Xie, Taylor Templeton-Jager

South Atlantic Division GME Research Day 2025

No abstract provided.


Immunotherapy-Induced Diabetes Mellitus Type 1: A New Perpetrator To The World Of Autoimmune Diabetes, Merid Moqattash, Dennis Besong Jan 2025

Immunotherapy-Induced Diabetes Mellitus Type 1: A New Perpetrator To The World Of Autoimmune Diabetes, Merid Moqattash, Dennis Besong

South Atlantic Division GME Research Day 2025

No abstract provided.


Renal Isolated Anti-Glomerular Basement Membrane Disease: A Diagnostic Challenge, Reggie Skains, Brooke Escoe, Jamie Campbell Jan 2025

Renal Isolated Anti-Glomerular Basement Membrane Disease: A Diagnostic Challenge, Reggie Skains, Brooke Escoe, Jamie Campbell

South Atlantic Division GME Research Day 2025

No abstract provided.


Systemic Lupus Erythematosus Presenting As Aseptic Meningitis And Pancytopenia, Julia Collins, Roy Escobar, Vishnu Halthore, Ali Abu-Alya, Tanvir Khosla, Hamza Hansoti, Janita Sidhu, Elia Barraza, Zachary Charif, Azaam Mamoor, Ann Wierman, Venkatachalam Veerappan Jan 2024

Systemic Lupus Erythematosus Presenting As Aseptic Meningitis And Pancytopenia, Julia Collins, Roy Escobar, Vishnu Halthore, Ali Abu-Alya, Tanvir Khosla, Hamza Hansoti, Janita Sidhu, Elia Barraza, Zachary Charif, Azaam Mamoor, Ann Wierman, Venkatachalam Veerappan

Far West Division GME Research Day 2024

No abstract provided.


Thymoma With Paraneoplastic Myasthenia Gravis, Dallin Beus, Sherwin Thomas, Amnah Andrabi Jan 2024

Thymoma With Paraneoplastic Myasthenia Gravis, Dallin Beus, Sherwin Thomas, Amnah Andrabi

North Texas GME Research Forum 2024

Background: Myasthenia gravis is an autoimmune neuromuscular disorder characterized by muscle weakness and fatigue. Paraneoplastic myasthenia gravis, a rare manifestation of this condition, is often associated with underlying malignancies, such as thymic tumors. We present the case of a 51-year-old female patient with a mediastinal mass who developed paraneoplastic myasthenia gravis, highlighting the diagnostic challenges and therapeutic considerations in such cases. Case Description: A 51-year-old female presented with a one-month history of progressive muscle weakness, diplopia, and dysphagia. Clinical examination and serological tests led to the diagnosis of myasthenia gravis. Computed tomography (CT) imaging revealed a 6 cm mediastinal mass, …


Alopecia Areata With Rapid Regrowth Following Oral Baricitinib Therapy, Seth Flynn, Molly Boyko, Mary Holly Glover Jan 2024

Alopecia Areata With Rapid Regrowth Following Oral Baricitinib Therapy, Seth Flynn, Molly Boyko, Mary Holly Glover

South Atlantic Division GME Research Day 2024

No abstract provided.


Mycophenolate Associated Progressive Multifocal Leukoencephalopathy In A Woman With Systemic Lupus Erythematosus, Zaur Komachkov, Yacoub Khatab Jan 2024

Mycophenolate Associated Progressive Multifocal Leukoencephalopathy In A Woman With Systemic Lupus Erythematosus, Zaur Komachkov, Yacoub Khatab

Gulf Coast Division GME Research Symposium 2024

No abstract provided.


An Atypical Presentation Of Systematic Lupys Erythematosus (Sle), Devante Shootes, Jeremiah Ling, Omer Farooq Jan 2024

An Atypical Presentation Of Systematic Lupys Erythematosus (Sle), Devante Shootes, Jeremiah Ling, Omer Farooq

Gulf Coast Division GME Research Symposium 2024

No abstract provided.


Anti-Glomerular Basement Membrane Disease Presenting With Renal Failure And Extensive Deep Venous Thrombosis, Alec Rhodes, Zainab Shakir, Lakshmi Tatineni, Sivatej Sarva, Ramesh Kesavan Jan 2023

Anti-Glomerular Basement Membrane Disease Presenting With Renal Failure And Extensive Deep Venous Thrombosis, Alec Rhodes, Zainab Shakir, Lakshmi Tatineni, Sivatej Sarva, Ramesh Kesavan

Gulf Coast Division GME Research Day 2023

No abstract provided.


Multiple Sclerosis In A 32-Year-Old Female With History Of Prolactinoma, Aleeza Ali, Jesse Simon, Adekunle Bamgboye Jan 2023

Multiple Sclerosis In A 32-Year-Old Female With History Of Prolactinoma, Aleeza Ali, Jesse Simon, Adekunle Bamgboye

East Florida Division GME Research Day 2023

Among disorders affecting the central nervous system (CNS), excluding trauma, multiple sclerosis (MS) is the most common cause of permanent disability in young adults. This condition is characterized by IgG autoantibody-mediated destruction of oligodendrocytes in the brain and spinal cord. Although the origin of MS is not fully understood, some suggest that prolactin may be involved in the development of the disease process evidenced by the fact that it predominately affects women of childbearing age, and the diverse role of prolactin (PRL) as a peptide hormone, cytokine, and immune modulator. Here we review the case of a 32-year-old female with …


Exploratory Analysis Of Outpatient Visits For Us Adults Diagnosed With Lupus Erythematosus: Findings From The National Ambulatory Medical Care Survey 2006–2016, Salena Marie Preciado, Khaled A. Elsaid, Souhiela Fawaz, Lawrence Brown, Enrique Seoane-Vazquez, Marc Fleming, Yun Wang Aug 2022

Exploratory Analysis Of Outpatient Visits For Us Adults Diagnosed With Lupus Erythematosus: Findings From The National Ambulatory Medical Care Survey 2006–2016, Salena Marie Preciado, Khaled A. Elsaid, Souhiela Fawaz, Lawrence Brown, Enrique Seoane-Vazquez, Marc Fleming, Yun Wang

Pharmacy Faculty Articles and Research

The study aims to assess office-based visit trends for lupus patients and evaluate their medication burden, chronic conditions, and comorbidities. This cross-sectional study used data from the National Ambulatory Medical Care Survey (NAMCS), a survey sample weighted to represent national estimates of outpatient visits. Adult patients diagnosed with lupus were included. Medications and comorbidities that were frequently recorded were identified and categorized. Descriptive statistics and bivariate analyses were used to characterize visits by sex, age, race/ethnicity, insurance type, region, and reason for visit. Comorbidities were identified using diagnosis codes documented at each encounter. There were 27,029,228 visits for lupus patients …


Covad Survey 2 Long-Term Outcomes: Unmet Need And Protocol, Zoha Zahid Fazal, Parikshit Sen, Mrudula Joshi, Naveen Ravichandran, James B. Lilleker, Vishwesh Agarwal, Sinan Kardes, Minchul Kim, Jessica Day, Ashima Makol Aug 2022

Covad Survey 2 Long-Term Outcomes: Unmet Need And Protocol, Zoha Zahid Fazal, Parikshit Sen, Mrudula Joshi, Naveen Ravichandran, James B. Lilleker, Vishwesh Agarwal, Sinan Kardes, Minchul Kim, Jessica Day, Ashima Makol

Medical College Documents

Vaccine hesitancy is considered a major barrier to achieving herd immunity against COVID-19. While multiple alternative and synergistic approaches including heterologous vaccination, booster doses, and antiviral drugs have been developed, equitable vaccine uptake remains the foremost strategy to manage pandemic. Although none of the currently approved vaccines are live-attenuated, several reports of disease flares, waning protection, and acute-onset syndromes have emerged as short-term adverse events after vaccination. Hence, scientific literature falls short when discussing potential long-term effects in vulnerable cohorts. The COVAD-2 survey follows on from the baseline COVAD-1 survey with the aim to collect patient-reported data on the long-term …


Temporal Changes In Gastrointestinal Fungi And The Risk Of Autoimmunity During Early Childhood: The Teddy Study, Thomas A Auchtung, Christopher J Stewart, Daniel P Smith, Eric W Triplett, Daniel Agardh, William A Hagopian, Anette G Ziegler, Marian J Rewers, Jin-Xiong She, Jorma Toppari, Åke Lernmark, Beena Akolkar, Jeffrey P Krischer, Kendra Vehik, Jennifer M Auchtung, Nadim J Ajami, Joseph F Petrosino Jun 2022

Temporal Changes In Gastrointestinal Fungi And The Risk Of Autoimmunity During Early Childhood: The Teddy Study, Thomas A Auchtung, Christopher J Stewart, Daniel P Smith, Eric W Triplett, Daniel Agardh, William A Hagopian, Anette G Ziegler, Marian J Rewers, Jin-Xiong She, Jorma Toppari, Åke Lernmark, Beena Akolkar, Jeffrey P Krischer, Kendra Vehik, Jennifer M Auchtung, Nadim J Ajami, Joseph F Petrosino

Faculty, Staff and Students Publications

Fungal infections are a major health problem that often begin in the gastrointestinal tract. Gut microbe interactions in early childhood are critical for proper immune responses, yet there is little known about the development of the fungal population from infancy into childhood. Here, as part of the TEDDY (The Environmental Determinants of Diabetes in the Young) study, we examine stool samples of 888 children from 3 to 48 months and find considerable differences between fungi and bacteria. The metagenomic relative abundance of fungi was extremely low but increased while weaning from milk and formula. Overall fungal diversity remained constant over …


Fever Of Unknown Origin: A Grave Diagnosis, Ryan Miller, Richard Allen Jan 2022

Fever Of Unknown Origin: A Grave Diagnosis, Ryan Miller, Richard Allen

South Atlantic Division GME Research Day 2022

No abstract provided.


Multi-Omics: Differential Expression Of Ifn-Γ Results In Distinctive Mechanistic Features Linking Chronic Inflammation, Gut Dysbiosis, And Autoimmune Diseases, Heekyong R. Bae, Patrick S. C. Leung, Deborah L. Hodge, John M. Fenimore, Seon Min Jeon, Vishal Thovarai, Amiran Dzutsev, Andrew A. Welcher, Michael Boedigheimer, Michael A. Damore, Myung Sook Choi, Richard A. Fravell, Giorgio Trinchieri, M. Eric Gershwin, Howard A. Young Jul 2020

Multi-Omics: Differential Expression Of Ifn-Γ Results In Distinctive Mechanistic Features Linking Chronic Inflammation, Gut Dysbiosis, And Autoimmune Diseases, Heekyong R. Bae, Patrick S. C. Leung, Deborah L. Hodge, John M. Fenimore, Seon Min Jeon, Vishal Thovarai, Amiran Dzutsev, Andrew A. Welcher, Michael Boedigheimer, Michael A. Damore, Myung Sook Choi, Richard A. Fravell, Giorgio Trinchieri, M. Eric Gershwin, Howard A. Young

United States Public Health Resources

Low grade, chronic inflammation is a critical risk factor for immunologic dysfunction including autoimmune diseases. However, the multiplicity of complex mechanisms and lack of relevant murine models limit our understanding of the precise role of chronic inflammation. To address these hurdles, we took advantage of multi-omics data and a unique murine model with a low but chronic expression of IFN-γ, generated by replacement of the AU-rich element (ARE) in the 3’ UTR region of IFN-γ mRNA with random nucleotides. Herein, we demonstrate that low but differential expression of IFN-γ in mice by homozygous or heterozygous ARE replacement triggers distinctive gut …