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Full-Text Articles in Diseases

Modeling In The Physiology Classroom, Sowmya Anjur Nov 2018

Modeling In The Physiology Classroom, Sowmya Anjur

Faculty Publications & Research

Physiology and Disease is a Biology elective at IMSA that has been developed to be mostly student-centered. Some examples of student projects include modeling heart structure to reflect function and creating LED arduino monitors to measure heart rate. Students also measure their lung capacity and blood pressure to demonstrate correlation of these values with heart rate, and trace the correlation back to neuronal controls. Projects such as these integrate other disciplines such as engineering and conform to NGSS Science and Engineering standards and NGSS Cross cutting Concepts standards. Students take responsibility for their own learning and articulate better on tests.


Cell Specific Control Of The Pallidostriatal Pathway, Shubha Verma '19 Nov 2018

Cell Specific Control Of The Pallidostriatal Pathway, Shubha Verma '19

Student Publications & Research

Parkinson’s Disease is a neurodegenerative disorder of the basal ganglia. The main cause for Parkinson’s Disease is the depletion of dopamine, a neurotransmitter. The basal ganglia contains four major nuclei: the substantia nigra, the subthalamic nucleus, the external globus pallidus, and the striatum. These nuclei communicate with each other by the use of neurons.


The Blue Baby, Lola Alao, Harsha Nalam '19, Dwanne Colobong '19, Trisha Sudhakar '19 Oct 2018

The Blue Baby, Lola Alao, Harsha Nalam '19, Dwanne Colobong '19, Trisha Sudhakar '19

Human Diseases Graphic Novels

No abstract provided.


Kidney Stones, Bopo Taiwo '20, Ishanpepe Jagusah '20 Oct 2018

Kidney Stones, Bopo Taiwo '20, Ishanpepe Jagusah '20

Human Diseases Graphic Novels

No abstract provided.


The Assassin Bug, Lola Alao '20, Harsha Nalam '19, Dwanne Colobong '19, Trisha Sudhakar '19 Oct 2018

The Assassin Bug, Lola Alao '20, Harsha Nalam '19, Dwanne Colobong '19, Trisha Sudhakar '19

Human Diseases Graphic Novels

No abstract provided.


Diseases At Work, Alice Liu '19, Nicholas Opiola '19, Gunnar Bergmann '19, Femi Durodola '20, Suraj Sunkara '19 Oct 2018

Diseases At Work, Alice Liu '19, Nicholas Opiola '19, Gunnar Bergmann '19, Femi Durodola '20, Suraj Sunkara '19

Human Diseases Graphic Novels

No abstract provided.


In The Office, Theo Heilman '19, Nathan Lee '19, Prachi Patil '19, Katie Si '19 Oct 2018

In The Office, Theo Heilman '19, Nathan Lee '19, Prachi Patil '19, Katie Si '19

Human Diseases Graphic Novels

No abstract provided.


A Humanized Hypertrophic Cardiomyopathy Model To Elucidate Molecular Mechanism In Disease Pathology, Ragavi Vijayakumar, Maxine Hong Jun 2018

A Humanized Hypertrophic Cardiomyopathy Model To Elucidate Molecular Mechanism In Disease Pathology, Ragavi Vijayakumar, Maxine Hong

The International Student Science Fair 2018

Hypertrophic cardiomyopathy (HCM), that clinically manifests as an enlarged heart is a highly prevalent cardiac disorder with propensity towards arrhythmia-induced sudden cardiac death. The mechanism of HCM remains poorly defined, necessitating further understanding of the disease for improved therapeutic strategies. As it is challenging to obtain cardiac biopsies from human subjects, using induced pluripotent stem cells technology, we generated cardiomyocytes (CMs) in a dish from HCM patients. These HCM-CMs presented the clinical manifestation in that they were significantly larger in size in comparison to control (healthy)-CMs. Furthermore, gene expression profiling of cardiac ion channels revealed increased transcripts encoding for calcium …


A Humanized Hypertrophic Cardiomyopathy Model To Elucidate Molecular Mechanism In Disease Pathology, Ragavi Vijayakumar, Maxine Hong Jun 2018

A Humanized Hypertrophic Cardiomyopathy Model To Elucidate Molecular Mechanism In Disease Pathology, Ragavi Vijayakumar, Maxine Hong

The International Student Science Fair 2018

Hypertrophic cardiomyopathy (HCM), that clinically manifests as an enlarged heart is a highly prevalent cardiac disorder with propensity towards arrhythmia-induced sudden cardiac death. The mechanism of HCM remains poorly defined, necessitating further understanding of the disease for improved therapeutic strategies. As it is challenging to obtain cardiac biopsies from human subjects, using induced pluripotent stem cells technology, we generated cardiomyocytes (CMs) in a dish from HCM patients. These HCM-CMs presented the clinical manifestation in that they were significantly larger in size in comparison to control (healthy)-CMs. Furthermore, gene expression profiling of cardiac ion channels revealed increased transcripts encoding for calcium …