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Full-Text Articles in Diseases
Can Viruses Cause Lupus?, Stephen I. Reeder
Can Viruses Cause Lupus?, Stephen I. Reeder
Selected Honors Theses
Like so many autoimmune diseases, the exact cause of systemic lupus erythematosus (SLE) remains unknown. Evidence points to both genetics and environment playing roles in the onset of the disease, but neither acts independent of the other. Genetics are the easier of the two to study with recent advances in the field making it easier to isolate genes shared by individuals with the disease. However, genetic studies reveal that there is almost certainly an environmental component to the development of SLE. The underlying pathology and existing research on environmental contributors to the development of SLE suggest that viruses could potentially …
The Severity And Lack Of Awareness Of Dermatomyositis, Alexander Lorenzo Perez Herrera
The Severity And Lack Of Awareness Of Dermatomyositis, Alexander Lorenzo Perez Herrera
Senior Theses
Dermatomyositis is a rare autoimmune disease that affects a very small percentage of the population, close to 10 cases per million, according to the National Organization of Rare Disorders (NORD). The amount of men that are diagnosed with this disease are even smaller. However, hardly anyone knows what Dermatomyositis is, let alone what its side effects are. The purpose of this research paper is to exploit the severity of Dermatomyositis for those who are unaware of its existence, characteristics and significance within the health community. In doing so, I hope to create awareness throughout society by also telling my father’s …
Role Of B Cell And Hematopoietic Cell Intrinsic Actions Of Erα In Lupus Pathogenesis, Dana E. Tabor
Role Of B Cell And Hematopoietic Cell Intrinsic Actions Of Erα In Lupus Pathogenesis, Dana E. Tabor
Theses & Dissertations
Lupus is a chronic autoimmune disease characterized by the presence of autoimmune B and T cells and the production of pathogenic antibodies against nuclear antigens. Lupus predominately affects women between menarche and menopause. There are both genetic and environmental risk factors which affect an individuals’ risk of developing lupus. Estrogens are a risk factor for developing lupus and are thought to contribute significantly to the initiation and progression of disease. In lupus-prone mice, genetic knockout of a receptor for estrogen, estrogen receptor alpha (ERα), causes significant attenuation of lupus. Previous studies have not identified the cell type or …