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Full-Text Articles in Diseases

The Effects Of Warfarin And Direct Oral Anticoagulants On Systemic Vascular Calcification: A Review, Kalaimani Elango, Awad Javaid, Banveet K. Khetarpal, Sathishkumar Ramalingam, Krishna Prasad Kolandaivel, Kulothungan Gunasekaran, Chowdhury Ahsan Mar 2021

The Effects Of Warfarin And Direct Oral Anticoagulants On Systemic Vascular Calcification: A Review, Kalaimani Elango, Awad Javaid, Banveet K. Khetarpal, Sathishkumar Ramalingam, Krishna Prasad Kolandaivel, Kulothungan Gunasekaran, Chowdhury Ahsan

School of Medicine Faculty Publications

Warfarin has been utilized for decades as an effective anticoagulant in patients with a history of strong risk factors for venous thromboembolism (VTE). Established adverse effects include bleeding, skin necrosis, teratogenicity during pregnancy, cholesterol embolization, and nephropathy. One of the lesser-known long-term side effects of warfarin is an increase in systemic arterial calcification. This is significant due to the association between vascular calcification and cardiovascular morbidity and mortality. Direct oral anticoagulants (DOACs) have gained prominence in recent years, as they require less frequent monitoring and have a superior side effect profile to warfarin, specifically in relation to major bleeding. The …


Risk Factors Associated With Cardiovascular Disease Among Adult Nevadans, Dieu My T. Tran, Nirmala Lekhak, Karen Gutierrez, Sheniz Moonie Feb 2021

Risk Factors Associated With Cardiovascular Disease Among Adult Nevadans, Dieu My T. Tran, Nirmala Lekhak, Karen Gutierrez, Sheniz Moonie

Nursing Faculty Publications

© 2021 Tran et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Objective Cardiovascular disease (CVD) remains the number one cause of death in the US and Nevada is ranked 11th highest for CVD mortality. The study sought to examine the association between self-reported risk factors and CVD presence among adult Nevadans, between years 2011 and 2017. Methods This is a cross-sectional, population-based study that utilized the 2011 and 2017 Nevada Behavioral Risk …