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Dietetics and Clinical Nutrition Commons

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Olivet Nazarene University

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2023

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Full-Text Articles in Dietetics and Clinical Nutrition

The Effects Of Creatine Supplementation On Muscle Synthesis And Fitness Levels In Drosophila Melanogaster Using A Model Of Muscle Atrophy, Kevin Williams May 2023

The Effects Of Creatine Supplementation On Muscle Synthesis And Fitness Levels In Drosophila Melanogaster Using A Model Of Muscle Atrophy, Kevin Williams

Honors Program Projects

This study examines whether an inhibited electron transport chain can be aided with supplemented creatine to make up for the challenged adenosine triphosphate (ATP) production mechanism. The electron transport chain is a series of protein complexes in the mitochondrial membrane that transfer electrons and couples this reaction with the transfer of protons across the membrane to produce ATP. The differences between male and female flies and the supplementation of creatine at a 0.15% concentration was studied. The relationship between these components was studied over the course of two 3-week trials using a fly treadmill and Drosophila. The effects of creatine …