Open Access. Powered by Scholars. Published by Universities.®
Dietetics and Clinical Nutrition Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Dietetics and Clinical Nutrition
The Effectiveness Of Smoflipid On Liver Function In Pediatric Patients With Intestinal Failure Related Parenteral Nutrition Associated Liver Disease (Pnald), Chelsey Kitazawa, Kara Bates, Shannon Lew
The Effectiveness Of Smoflipid On Liver Function In Pediatric Patients With Intestinal Failure Related Parenteral Nutrition Associated Liver Disease (Pnald), Chelsey Kitazawa, Kara Bates, Shannon Lew
Loma Linda University Research Reports
Abstract
Background:Parenteral nutrition (PN) is a treatment that supplies one's nutrition and hydration needs intravenously. Intravenous soybean lipid emulsions have been associated with Parenteral Nutrition Associated Liver Disease (PNALD), due to its high phytosterol content and high n-6:n-3 ratio and its propensity to mitigate inflammatory eicosanoid pathways. Composed of soybean oil, medium chain fatty acids, olive oil, and fish oil, Smoflipid may ameliorate PNALD and mitigate anti-inflammatory eicosanoid pathways.
Objective: To examine the effectiveness of Smoflipid on improving liver function and bilirubin levels on home PN-dependent children with intestinal failure related PNALD.
Design: A prospective electronic medical record review …