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Prosthodontics and Prosthodontology Commons™
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- Streptococcus mutans (2)
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Articles 1 - 14 of 14
Full-Text Articles in Prosthodontics and Prosthodontology
Effect Of Margin Thickness And Cement Gap On The Fabrication And Fit Accuracy Of Additively Manufactured Crowns In Definitive Resins With Different Filler Content, Mustafa Borga Dönmez, Gülce Çakmak, Çiğdem Kahveci, Amir H. Nejat, Burak Yilmaz, Pinar Altinci
Effect Of Margin Thickness And Cement Gap On The Fabrication And Fit Accuracy Of Additively Manufactured Crowns In Definitive Resins With Different Filler Content, Mustafa Borga Dönmez, Gülce Çakmak, Çiğdem Kahveci, Amir H. Nejat, Burak Yilmaz, Pinar Altinci
School of Dentistry Faculty Publications
PURPOSE: To evaluate how commercially available composite resins in varying filler content affect the fabrication and fit accuracy (trueness and precision) of additively manufactured (AM) definitive crowns with different margin thickness and cement gaps by comparing them to subtractively manufactured (SM) polymer-infiltrated ceramic crowns. MATERIALS AND METHODS: Two identical unprepared mandibular right first molars were prepared by an experienced prosthodontist for crowns with either 0.5 mm or 1.0 mm chamfer margins, verified using silicone indexes and a periodontal probe, and then digitized with an industrial-grade scanner. These scan files were used to design reference crowns with either 50-µm or 80-µm …
Effect Of Build Orientation On The Fabrication Trueness Of Additively Manufactured Implant-Supported Complete Arch Interim Fixed Prostheses, Amir H. Nejat, Mehmet Esad Güven, Gülce Çakmak, Burak Yilmaz, Mustafa Borga Donmez
Effect Of Build Orientation On The Fabrication Trueness Of Additively Manufactured Implant-Supported Complete Arch Interim Fixed Prostheses, Amir H. Nejat, Mehmet Esad Güven, Gülce Çakmak, Burak Yilmaz, Mustafa Borga Donmez
School of Dentistry Faculty Publications
PURPOSE: To evaluate how build orientation affects the fabrication trueness of additively manufactured implant-supported complete arch prostheses by comparing them to subtractively manufactured high-impact polymer-based prostheses. MATERIALS AND METHODS: An edentulous maxillary model with four implants at canine and first molar regions bilaterally was digitized (ATOS Core 80 5MP) to design a reference implant-supported complete arch prosthesis standard tessellation language file (RF-STL). The STL file was used to manufacture prostheses additively in five different orientations according to the build platform (AM-0, 0-degree; AM-15, 15-degree; AM-30, 30-degree; AM-45, 45-degree; AM-90, 90-degree) or subtractively (SM-HIP, control) (n = 10). The prostheses were …
The Effect Of Die Material On The Crown Fracture Strength Of Zirconia Crowns, Akram Sayed Ahmed, Nathaniel C. Lawson, Chin-Chuan Fu, Pranit V. Bora, Edwin Kee, Amir H. Nejat
The Effect Of Die Material On The Crown Fracture Strength Of Zirconia Crowns, Akram Sayed Ahmed, Nathaniel C. Lawson, Chin-Chuan Fu, Pranit V. Bora, Edwin Kee, Amir H. Nejat
School of Dentistry Faculty Publications
BACKGROUND: Determination of the eligibility of several tooth analog materials for use in crown fracture testing. METHODS: A standardized premolar crown preparation was replicated into three types of resin dies (C&B, low modulus 3D printed resin; OnX, high modulus 3D printed resin composite; and highest modulus milled resin composite). 0.8 mm zirconia crowns were bonded to the dies and the maximum fracture load of the crowns was tested. Twelve extracted human premolars were prepared to a standardized crown preparation, and duplicate dies of the prepared teeth were 3D printed out of C&B. Zirconia crowns were bonded to both the dies …
Bond Strength Of Reline Materials To 3d-Printed Provisional Crown Resins, Jorge Palavicini, Sherrod L. Quin, Wael Zakkour, Karim Zakkour, Safa Manafi Varkiani, Xiaoming Xu, Nathaniel C. Lawson, Amir Hossein Nejat
Bond Strength Of Reline Materials To 3d-Printed Provisional Crown Resins, Jorge Palavicini, Sherrod L. Quin, Wael Zakkour, Karim Zakkour, Safa Manafi Varkiani, Xiaoming Xu, Nathaniel C. Lawson, Amir Hossein Nejat
School of Dentistry Faculty Publications
(1) Purpose: The aim of the present study was to compare the bond strength between two 3D-printed resins designed for long-term provisional crowns and three different reline materials. (2) Materials and Methods: Rectangular specimens were prepared from two 3D-printed resins (Envision Tech and NextDent C&B) and a conventional self-cure PMMA. Transparent tubes filled with three different reline materials including composite resin, Bis-acryl, and PMMA were bonded to the 3D-printed specimens (n = 11 per group, total of 6 study groups). Tubes filled with PMMA were bonded to the prepared PMMA specimens which served as the control group (n = 11, …
Impacts Of A Duf2207 Family Protein On Streptococcus Mutans Stress Tolerance Responses And Biofilm Formation, Xiaochang Huang, Camile G. Laird, Paul P. Riley, Zezhang Tom Wen
Impacts Of A Duf2207 Family Protein On Streptococcus Mutans Stress Tolerance Responses And Biofilm Formation, Xiaochang Huang, Camile G. Laird, Paul P. Riley, Zezhang Tom Wen
School of Dentistry Faculty Publications
Locus SMU.243 in Streptococcus mutans was annotated as a member of the DUF2207 family proteins highly conserved in all bacteria but with unknown function. To investigate its role in S. mutans physiology, a SMU.243-deficient mutant was constructed using allelic exchange mutagenesis, and the impacts of SMU.243 deletion on bacterial growth, stress tolerance response, and biofilm formation were analyzed. Compared to the wild-type UA159, S. mutans lacking SMU.243 displayed a reduced growth rate and a reduced overnight culture density (p < 0.01) when grown at low pH and in the presence of methyl viologen. Relative to the parent strain, the deficient mutant also had a reduced survival rate following incubation in a buffer of pH 2.8 (p < 0.01) and in a buffer containing hydrogen peroxide at 58 mM after 60 min (p < 0.001) and had a reduced capacity in biofilm formation especially in the presence of sucrose (p < 0.01). To study any ensuing functional/phenotypical links between SMU.243 and uppP, which is located immediately downstream of SMU.243 and encodes an undecaprenyl pyrophosphate phosphatase involved in recycling of carrier lipid undecaprenyl phosphate, a uppP deficient mutant was generated using allelic exchange mutagenesis. Unlike the SMU.243 mutant, deletion of uppP affected cell envelope biogenesis and caused major increases in susceptibility to bacitracin. In addition, two variant morphological mutants, one forming rough colonies and the other forming mucoid, smooth colonies, also emerged following the deletion of uppP. The results suggest that the SMU.243-encoded protein of the DUF2207 family in S. mutans plays an important role in stress tolerance response and biofilm formation, but unlike the downstream uppP, does not seem to be involved in cell envelope biogenesis, although the exact roles in S. mutans’ physiology awaits further investigation.
Current Oral Hygiene And Recreational Behavioral Trends In Hiv Disease, Donald E. Mercante, Emily Guarisco, Elizabeth A. Lilly, Arni Rao, Kelly Treas, Clifford J. Beall, Zach Thompson, Ann L. Griffen, Eugene J. Leys, Jose A. Vazquez, Michael E. Hagensee, Paul L. Fidel
Current Oral Hygiene And Recreational Behavioral Trends In Hiv Disease, Donald E. Mercante, Emily Guarisco, Elizabeth A. Lilly, Arni Rao, Kelly Treas, Clifford J. Beall, Zach Thompson, Ann L. Griffen, Eugene J. Leys, Jose A. Vazquez, Michael E. Hagensee, Paul L. Fidel
School of Dentistry Faculty Publications
Objective: HIV disease is evolving with more HIV+ persons experiencing a high quality of life with well-controlled viremia. We recently enrolled a large cohort of HIV+ and clinically relevant HIV− persons for oral microbiome analyses that included a questionnaire related to oral hygiene and recreational behaviors. Here, the questionnaire responses were analyzed for behavioral trends within the cohort, together with trends over time by comparison to a previous geographically centered HIV+ cohort. Methods: Data were collected by questionnaire at baseline visits as cross-sectional assessments. Multivariable analyses were conducted for associations of HIV status as well as age, race, and sex, …
Defining Success In Healthcare Education: Us Dental Student And Faculty Perspectives., David Alexandre Cruz Walma, Mathieu Alexander Cruz Walma, Shirin Khoynezhad, Sang E. Park, Carly Timmons Mckenzie, Et Al
Defining Success In Healthcare Education: Us Dental Student And Faculty Perspectives., David Alexandre Cruz Walma, Mathieu Alexander Cruz Walma, Shirin Khoynezhad, Sang E. Park, Carly Timmons Mckenzie, Et Al
School of Dentistry Faculty Publications
Purpose/objectives Academic metrics and clinical performance are necessary but alone insufficient in describing success in dental education. This paper identifies themes critical for dental student success as commonly cited by both dental students and faculty. Methods Dental faculty interviews and pre-doctoral D2/D3/D4 student focus groups at two dental institutions generated data for thematic analysis. Themes were individually identified then merged, compared, and contrasted to establish a definitive list of key themes reflected in student and faculty comments. Results Twenty-five pre-doctoral students participated in one of four focus groups (two focus groups at each dental institution). Thirteen dental education faculty across …
Acceptability Of Fully Guided Virtual Implant Planning Software Among Dental Undergraduate Students, Shishir Ram Shetty, Colin Murray, Sausan Al Kawas, Sara Jaser, Wael Talaat, Medhini Madi, Vinayak Kamath, Nisha Manila, Raghavendra Shetty, Vidya Ajila
Acceptability Of Fully Guided Virtual Implant Planning Software Among Dental Undergraduate Students, Shishir Ram Shetty, Colin Murray, Sausan Al Kawas, Sara Jaser, Wael Talaat, Medhini Madi, Vinayak Kamath, Nisha Manila, Raghavendra Shetty, Vidya Ajila
School of Dentistry Faculty Publications
Background: Fully guided implant surgery as a technique is gaining popularity. It has been observed that use of surgical guides improves precision and predictability for dental implant placement. However, like any other newer technology, the acceptance of fully guided dental implant technology among users is based upon its perceived usability. This study aimed at evaluating the perception about using Virtual Implant Planning Software (VIPS) among undergraduate dental students at the university of Sharjah. Methods: Ninety-Six dental surgery students from the University of Sharjah were included in the study. One week after the Virtual Implant Planning Software (Planmeca Romexis version 6.2 …
Independent Effects Of Hiv And Antiretroviral Therapy On The Oral Microbiome Identified By Multivariate Analyses, Clifford J. Beall, Elizabeth A. Lilly, Carolina Granada, Kelly Treas, Kenneth R. Dubois, Shahr B. Hashmi, Jose A. Vazquez, Michael E. Hagensee, Ann L. Griffen, Eugene J. Leys, Paul L. Fidel
Independent Effects Of Hiv And Antiretroviral Therapy On The Oral Microbiome Identified By Multivariate Analyses, Clifford J. Beall, Elizabeth A. Lilly, Carolina Granada, Kelly Treas, Kenneth R. Dubois, Shahr B. Hashmi, Jose A. Vazquez, Michael E. Hagensee, Ann L. Griffen, Eugene J. Leys, Paul L. Fidel
School of Dentistry Faculty Publications
The oral microbiome is an important predictor of health and disease. We recently reported significant yet modest effects of HIV under highly active antiretroviral therapy (ART) on the oral microbiome (bacterial and fungal) in a large cohort of HIV-positive (HIV+) and matched HIV-negative (HIV-) individuals. As it was unclear whether ART added to or masked further effects of HIV on the oral microbiome, the present study aimed to analyze the effects of HIV and ART independently, which also included HIV- subjects on preexposure prophylaxis (PrEP) therapy. Cross-sectional analyses of the effect of HIV devoid of ART (HIV+ ART- versus matched …
Revised Fdi Criteria For Evaluating Direct And Indirect Dental Restorations—Recommendations For Its Clinical Use, Interpretation, And Reporting, Reinhard Hickel, Sabine Mesinger, Niek Opdam, Bas Loomans, Roland Frankenberger, Milena Cadenaro, John Burgess, Arnd Peschke, Siegward D. Heintze, Jan Kühnisch
Revised Fdi Criteria For Evaluating Direct And Indirect Dental Restorations—Recommendations For Its Clinical Use, Interpretation, And Reporting, Reinhard Hickel, Sabine Mesinger, Niek Opdam, Bas Loomans, Roland Frankenberger, Milena Cadenaro, John Burgess, Arnd Peschke, Siegward D. Heintze, Jan Kühnisch
School of Dentistry Faculty Publications
Objectives: The FDI criteria for the evaluation of direct and indirect dental restorations were first published in 2007 and updated in 2010. Meanwhile, their scientific use increased steadily, but several questions from users justified some clarification and improvement of the living document. Materials and methods: An expert panel (N = 10) initiated the revision and consensus process that included a kick-off workshop and multiple online meetings by using the Delphi method. During and after each round of discussion, all opinions were collected, and the aggregated summary was presented to the experts aiming to adjust the wording of the criteria as …
The Effect Of Silver Diamine Fluoride On Bond Strength Of Three Types Of Bulk-Fill Restorative Materials To Dentin., Nasrin Danaeifar, Amir Hossein Nejat, Zafar Cehreli, Richard W. Ballard, Jeffrey T. Johnson
The Effect Of Silver Diamine Fluoride On Bond Strength Of Three Types Of Bulk-Fill Restorative Materials To Dentin., Nasrin Danaeifar, Amir Hossein Nejat, Zafar Cehreli, Richard W. Ballard, Jeffrey T. Johnson
School of Dentistry Faculty Publications
No abstract provided.
A Small Molecule Produced By Lactobacillus Species Blocks Candida Albicans Filamentation By Inhibiting A Dyrk1-Family Kinase, Jessie Macalpine, Martin Daniel-Ivad, Zhongle Liu, Junko Yano, Nicole M. Revie, Robert T. Todd, Peter J. Stogios, Hiram Sanchez, Teresa R. O’Meara, Thomas A. Tompkins, Alexei Savchenko, Anna Selmecki, Amanda O. Veri, David R. Andes, Paul L. Fidel, Nicole Robbins, Justin Nodwell, Luke Whitesell, Leah E. Cowen
A Small Molecule Produced By Lactobacillus Species Blocks Candida Albicans Filamentation By Inhibiting A Dyrk1-Family Kinase, Jessie Macalpine, Martin Daniel-Ivad, Zhongle Liu, Junko Yano, Nicole M. Revie, Robert T. Todd, Peter J. Stogios, Hiram Sanchez, Teresa R. O’Meara, Thomas A. Tompkins, Alexei Savchenko, Anna Selmecki, Amanda O. Veri, David R. Andes, Paul L. Fidel, Nicole Robbins, Justin Nodwell, Luke Whitesell, Leah E. Cowen
School of Dentistry Faculty Publications
The fungus Candida albicans is an opportunistic pathogen that can exploit imbalances in microbiome composition to invade its human host, causing pathologies ranging from vaginal candidiasis to fungal sepsis. Bacteria of the genus Lactobacillus are colonizers of human mucosa and can produce compounds with bioactivity against C. albicans. Here, we show that some Lactobacillus species produce a small molecule under laboratory conditions that blocks the C. albicans yeast-to-filament transition, an important virulence trait. It remains unexplored whether the compound is produced in the context of the human host. Bioassay-guided fractionation of Lactobacillus-conditioned medium linked this activity to 1-acetyl-β-carboline (1-ABC). We …
Leukotrienes Are Dispensable For Vaginal Neutrophil Recruitment As Part Of The Immunopathological Response During Experimental Vulvovaginal Candidiasis, Junko Yano, David J. White, Anthony P. Sampson, Floyd L. Wormley, Paul L. Fidel
Leukotrienes Are Dispensable For Vaginal Neutrophil Recruitment As Part Of The Immunopathological Response During Experimental Vulvovaginal Candidiasis, Junko Yano, David J. White, Anthony P. Sampson, Floyd L. Wormley, Paul L. Fidel
School of Dentistry Faculty Publications
Recruitment of polymorphonuclear neutrophils (PMNs) into the vaginal lumen is the hallmark of an acute immunopathologic inflammatory response during vulvovaginal candidiasis (VVC) caused by Candida albicans. Recurrent VVC (RVVC) remains a chronic health burden in affected women worldwide despite the use of antifungal therapy. Based on the role leukotrienes (LTs) play in promoting inflammation, leukotriene receptor antagonists (LTRAs) targeted for LTB4 (etalocib) or LTC4, LTD4, and LTE4 (zafirlukast or montelukast) have been shown to reduce inflammation of epithelial tissues. An open-label pilot study using long-term regimens of zafirlukast in women with RVVC indicated the potential for some relief from recurrent …
Streptococcus Mutans Lacking Sufcdsub Is Viable, But Displays Major Defects In Growth, Stress Tolerance Responses And Biofilm Formation, Kassapa Ellepola, Xiaochang Huang, Ryan P. Riley, Jacob P. Bitoun, Zezhang Tom Wen
Streptococcus Mutans Lacking Sufcdsub Is Viable, But Displays Major Defects In Growth, Stress Tolerance Responses And Biofilm Formation, Kassapa Ellepola, Xiaochang Huang, Ryan P. Riley, Jacob P. Bitoun, Zezhang Tom Wen
School of Dentistry Faculty Publications
Streptococcus mutans appears to possess a sole iron-sulfur (Fe-S) cluster biosynthesis system encoded by the sufCDSUB cluster. This study was designed to examine the role of sufCDSUB in S. mutans physiology. Allelic exchange mutants deficient of the whole sufCDSUB cluster and in individual genes were constructed. Compared to the wild-type, UA159, the sufCDSUB-deficient mutant, Δsuf::kanr, had a significantly reduced growth rate, especially in medium with the absence of isoleucine, leucine or glutamate/glutamine, amino acids that require Fe-S clusters for biosynthesis and when grown with medium adjusted to pH 6.0 and under oxidative and nitrosative stress conditions. Relative to UA159, Δsuf::kanr …