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Oral Biology and Oral Pathology Commons™
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- Journal Paper (3)
- Oral squamous cell carcinoma (2)
- Adaptive network based fuzzy inference system (1)
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- Cytotoxicity; polyurethane; dimethacrylate; palm oil; polyol; SELF-REPAIR; CULTURE-CONDITIONS; COMPOSITE RESIN; DENTAL PULP STEM CELL; FUNCTIONALLY GRADED DESIGN; MULTI LAYERED POST; FUNCTIONALLY GRADED DENTAL POST; SOFT SKILLS; CLINICAL PAIRING; DENTAL PULP STROMAL CELLS; LONG-TERM EXPANSION (1)
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- Formalin-fixed paraffin-embedded tissues (1)
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Articles 1 - 6 of 6
Full-Text Articles in Oral Biology and Oral Pathology
Thermo-Mechanical Stress In Multilayered Dental Post Due To Temperature Gradient, Noor Hayaty Abu Kasim Abu Kasim N.H.
Thermo-Mechanical Stress In Multilayered Dental Post Due To Temperature Gradient, Noor Hayaty Abu Kasim Abu Kasim N.H.
Noor Hayaty Abu Kasim Abu Kasim N.H.
Objective: To analyse thermo-mechanical stress in endodontically treated teeth restored with Multilayered Structured Dental Posts (MSDPs) under cold and hot conditions using Finite Element Analysis (FEM). Methods: Three MSDPs of multilayer design of xTi-yHA composition added to a zirconia layer (model A), an alumina layer (model B) and a titanium layer (model C) were compared with zirconia (model D) and titanium (model E) posts. The fractions of Ti and HA was varied gradually. Changes in temperature of an endodontically restored tooth model were calculated as a result of hot and cold response. The resulting thermo-mechanical stresses were analysed and compared …
Genetic Polymorphisms And Risk Of Oral Cancer, Zaini Z. M., Karen-Ng L. P., Cheong S. C., Gurdeep S. M., Yuen K. M., Tay K. K., Jalil N., Ismail S. M., Jallaluddin A., Rosnah Binti Zain
Genetic Polymorphisms And Risk Of Oral Cancer, Zaini Z. M., Karen-Ng L. P., Cheong S. C., Gurdeep S. M., Yuen K. M., Tay K. K., Jalil N., Ismail S. M., Jallaluddin A., Rosnah Binti Zain
Prof. Dr. Rosnah Binti Zain
Objectives: This study was done to investigate the role of single nucleotide polymorphisms(SNPs) within genes of phase I (CYP1A1) and phase II (GSTM1, GSTT1,GSTP1) of the xenobiotic metabolism and its association with oral cancer risk.Methods: An unmatched case-control study was conducted using 207 newly diagnosed oral cancer patients and 117 non-cancer subjects selected from the OCRCC database. Peripheral blood was obtained from consented individuals and the CYP1A1, GSTM1, GSTT1 and GSTP1 genotypes were determined using polymerase chain reaction (PCR) and restriction enzyme digestion (RFLP). Simple and multiple logistic regression yielding odds ratio (OR and aOR) were employed to measure the …
Transcriptional Profiling Of Oral Squamous Cell Carcinoma Using Formalin-Fixed Paraffin-Embedded Samples, Saleh A., Rosnah Binti Zain, Hussaini H., Ng F., Tanavde V., Hamid S., Chow A. T., Lim G. S., Abraham M. T., Teo S. H., Cheong S. C.
Transcriptional Profiling Of Oral Squamous Cell Carcinoma Using Formalin-Fixed Paraffin-Embedded Samples, Saleh A., Rosnah Binti Zain, Hussaini H., Ng F., Tanavde V., Hamid S., Chow A. T., Lim G. S., Abraham M. T., Teo S. H., Cheong S. C.
Prof. Dr. Rosnah Binti Zain
Despite the advances in cancer treatment, the 5-year survival rate for oral cancer has not changed significantly for the past 40 years and still remains among the worst of all anatomic sites. Gene expression microarrays have been used successfully in the identification of genetic alterations in cancer development, however, these have hitherto been limited by the need for specimens with good quality intact RNA. Here, we demonstrated the use of formalin-fixed paraffin-embedded tissues in microarray experiments to identify genes differentially expressed between cancerous and normal oral tissues. Forty-three tissue samples were macrodissected and gene expression analyses were conducted using the …
A Bootstrap-Anfis Framework For Oral Cancer Prognosis Based On Clinical And Genomic Markers, Chang S. W., Sameem A. K., Rosnah Binti Zain, Merican A. F. M. A.
A Bootstrap-Anfis Framework For Oral Cancer Prognosis Based On Clinical And Genomic Markers, Chang S. W., Sameem A. K., Rosnah Binti Zain, Merican A. F. M. A.
Prof. Dr. Rosnah Binti Zain
The incidence of oral cancer is high in Malaysia especially for those of Indian ethnic origin. In this research, an oral cancer prognosis prediction model will be developed by using Bootstrap-ANFIS techniques. The aim of this research is to improve the prediction of oral cancer survival and to identify the key clinical and genomic markers for the survival prediction of oral cancer. The proposed model is designed to handle small medical dataset with limitations in terms of time, cost and tissue samples.
Cytotoxicity Of Polyurethane Dimethacrylate Derived From Palm Oil Polyol., Noor Hayaty Abu Kasim Abu Kasim N.H.
Cytotoxicity Of Polyurethane Dimethacrylate Derived From Palm Oil Polyol., Noor Hayaty Abu Kasim Abu Kasim N.H.
Noor Hayaty Abu Kasim Abu Kasim N.H.
Objective: The aim of this study was to investigate the cytotoxicity effect of polyurethane dimethacrylate monomer derived from palm oil polyol (PUDMA) and 2 experimental composite resins based on these monomer PUDMA- based composites) compared to an experimental Bis-GMA/TEGDMA-based composite and EsthetX flowable composite (Dentsply, Caulk, USA). Methods: The experimental composite resins were prepared by mixing 0.25% and 0.75% by weight camphorquinone and ethyl (4-dimethyl amino) benzoate with 60% filler for each of the following monomer systems; I) PUDMA monomer (PUDMA-based composite resin), II) Bis-GMA/TEGDMA at ratio of 75:25 by weight, III) PUDMA/BisGMA-TEGDMA at ratio of 50:50 by weight. Eight …
Surface Reproduction Of Elastomeric Materials: Viscosity And Groove Shape Effects, Noor Hayaty Abu Kasim Abu Kasim N.H.
Surface Reproduction Of Elastomeric Materials: Viscosity And Groove Shape Effects, Noor Hayaty Abu Kasim Abu Kasim N.H.
Noor Hayaty Abu Kasim Abu Kasim N.H.
Objective: To evaluate the effect of viscosity and type of grooves on surface detail reproduction of elastomeric impression materials. Methods: Express putty/light-, Impregum medium- and heavy/light-bodied and Aquasil medium- and putty/light-bodied elastomeric impression materials were chosen for this study. Five impressions were made using a cylindrical aluminum reference block with U- and V- shaped grooves and to produce 35 master dies. Each master die was immersed in distilled water at 370 C for 5 minutes prior to the impression making on moist surfaces. Surface topography of the dies and impressions were captured using Alicona Imaging System. The mean difference in …