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Full-Text Articles in Oral Biology and Oral Pathology
Significant Association Of High-Risk Human Papillomavirus (Hpv) But Not Of P53 Polymorphisms With Oral Squamous Cell Carcinomas In Malaysia, Saini R., Tang T. H., Rosnah Binti Zain, Cheong S. C., Musa K. I., Saini D., Ismail A. R., Abraham M. T., Mustafa W. M. W., Santhanam J.
Significant Association Of High-Risk Human Papillomavirus (Hpv) But Not Of P53 Polymorphisms With Oral Squamous Cell Carcinomas In Malaysia, Saini R., Tang T. H., Rosnah Binti Zain, Cheong S. C., Musa K. I., Saini D., Ismail A. R., Abraham M. T., Mustafa W. M. W., Santhanam J.
Prof. Dr. Rosnah Binti Zain
Purpose: The purpose of this study was to evaluate the role of HPV and p53 polymorphisms in oral squamous cell carcinomas (OSCC) affecting Malaysian population. Methods: We analysed frozen samples from 105 OSCC as well as 105 oral specimens derived from healthy individuals. PCR assays targeting two regions of the virus were used. PCR amplification for the analysis of p53 codon 72 arginine/proline alleles was carried out in a separate reaction. Results: HPV DNA was detected in 51.4% OSCC samples, while 24.8% controls were found to be HPV positive. HPV was found to be significantly associated with OSCC (P < 0.001, …
Factors Affecting Commencement And Cessation Of Betel Quid Chewing Behaviour In Malaysian Adults., Ghani W. M. N., Razak I. A., Yang Y. H., Talib N. A., Ikeda N., Axell T., Gupta P. C., Handa Y., Abdullah N., Rosnah Binti Zain
Factors Affecting Commencement And Cessation Of Betel Quid Chewing Behaviour In Malaysian Adults., Ghani W. M. N., Razak I. A., Yang Y. H., Talib N. A., Ikeda N., Axell T., Gupta P. C., Handa Y., Abdullah N., Rosnah Binti Zain
Prof. Dr. Rosnah Binti Zain
Background. Betel quid chewing is a common habit widely practiced in Southern Asian populations. However, variations are seen in the content of a betel quid across the different countries. Factors associated with commencement and cessation of this habit has been numerously studied. Unfortunately, data on Malaysian population is non-existent. This study aims to determine the factors associated with the inception and also cessation of betel quid chewing behaviour among Malaysian adults. Method. This study is part of a nationwide survey on oral mucosal lesions carried out among 11,697 adults in all fourteen states in Malaysia. The questionnaire included sociodemographic information …