Oral and Maxillofacial Surgery Commons^™

Resorbable Barrier Effect In Sinus Graft Using Anorganic Bone, Kyung-Soo Choi

Loma Linda University Electronic Theses, Dissertations & Projects

The effect of a resorbable membrane on new bone formation in human maxillary sinus augmentation using anorganic bovine material is unclear at the present time. As a pilot study, six patients who required bilateral maxillary sinus augmentations for endoessous dental implant treatment were grafted with anorganic bovine bone material. All six patients had a resorbable collagen membrane placed over the graft material on only one side for the sinus augmentation. At the time of implant placement, a minimum of 8 months following sinus graft healing, a biopsy was made of each side to permit histomorphometric analysis.

Similar amounts of new …

A Continued Investigation Of Craniofacial Growth In Infant Heart Transplant Recipients Receiving Cyclosporine, Gabriel Enriquez

Loma Linda University Electronic Theses, Dissertations & Projects

Since the mid 1980’s, Cyclosporine has proved to be an effective immunosuppressive drug and now has a widespread application in organ transplantation. Several studies, however, have implicated cyclosporine as adversely affecting craniofacial growth in the pediatric population. ^16,18 The purpose of this follow-up study was to continue to evaluate the possible untoward effects of long-term use of cyclosporine on craniofacial growth in a group of infant heart transplantation recipients by re-evaluating as many subjects as possible from the original study and evaluating new subjects. A pediatric group (N=13) was composed of six Caucasian subjects (4 male and 2 female, ages …

Implant Success In Distracted Bone Versus Autogenous Bone-Grafted Sites, Jeffrey Allan Elo

Loma Linda University Electronic Theses, Dissertations & Projects

Endosseous implants are the treatment of choice for restoring function and reconstructing edentulous areas of the maxilla and mandible. Alveolar defects can be reconstructed by either distraction osteogenesis or autogenous bone grafting. After alveolar reconstruction, endosseous implants are used to support and retain the prosthesis for restoration of form and function. We retrospectively analyzed the success rates of endosseous implant placement in distracted versus autogenous bone graft reconstruction sites in our patient population at Loma Linda University Medical Center, Department of Oral and Maxillofacial Surgery. 82 consecutive patients requiring alveolar augmentation prior to implant placement were evaluated. All patients were …

Bone Morphogenic Protein Induced Repair Of The Premaxillary Cleft, Rick J. Rawson

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study is to evaluate the bony augmentation of premaxillary clefts in humans using recombinant bone morphogenic protein (rhBMP-2) in a collagen sponge carrier. 12 patients with unilateral cleft alveolar ridges were evaluated pre- and 4 months postoperatively. 10 patients were repaired with rhBMP-2 while two others were grafted with anterior iliac crest particulate marrow cancellous bone (PMCB). Computed tomographic studies were used to evaluate preoperative alveolar cleft volumes, postoperative bone bridge volumes, and pre/post operative volume ratios.

A pre/post operative volume ratio for patients repaired with rhBMP-2 ranged from 24.1% to 90.6% with a mean of …

Mineralized Bone Allograft In Maxillary Sinuses Histology And Histomorphometry, Sammy Stefan Noumbissi

Loma Linda University Electronic Theses, Dissertations & Projects

Background: Demineralized freeze-dried bone allografts (DFDBA) and deproteinized bovine bone xenografts (DMBBX) have been used for sinus augmentation for many years with varying results, but very little has been reported on the clinical efficacy or the histological analysis of mineralized solvent dehydrated bone allografts (MSDBA) as sinus graft materials. This study histologically and histomorphometrically evaluated an MSDBA material called PUROS to augment atrophic human maxillary sinuses.

Materials & Methods: Seven partially and completely edentulous patients requiring unilateral (n=4) or bilateral (n=3) sinus grafts prior to implant placement were selected for this study. Test grafts consisted of MSDBA, and control …