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Full-Text Articles in Dental Hygiene
Oral Microbiome And Gingival Tissue Apoptosis And Autophagy Transcriptomics, Jeffrey L. Ebersole, Sreenatha S. Kirakodu, Elliot Neumann, Luis Orraca, Janis Gonzalez Martinez, Octavio A. Gonzalez
Oral Microbiome And Gingival Tissue Apoptosis And Autophagy Transcriptomics, Jeffrey L. Ebersole, Sreenatha S. Kirakodu, Elliot Neumann, Luis Orraca, Janis Gonzalez Martinez, Octavio A. Gonzalez
Dental Medicine Faculty Research
Objective: This study focused on documenting characteristics of the gingival transcriptome during various stages of periodontitis targeting genes associated with apoptotic and autophagic pathways and changes that specifically associate with features of the oral microbiome. Methods: Macaca mulatta (n = 18; 12-23 years) were examined at baseline and 0.5, 1, and 3 months of disease progression, as well as 5 months with clinical disease resolution. 16S sequencing and microarray analyses examined changes in the microbiome and gingival transcriptome, respectively, at each time point from every animal. Results: Specific patterns of apoptotic and autophagic genes were identified related to the initiation …
Efficacy Of An Anhydrous Stannous Fluoride Toothpaste For Relief Of Dentine Hypersensitivity: A Randomized Clinical Study, Danying Tao, Martin R. Ling, Xi-Ping Feng, John Gallob, Audrey Souverain, Wenjie Yang, Anousheh Alavi
Efficacy Of An Anhydrous Stannous Fluoride Toothpaste For Relief Of Dentine Hypersensitivity: A Randomized Clinical Study, Danying Tao, Martin R. Ling, Xi-Ping Feng, John Gallob, Audrey Souverain, Wenjie Yang, Anousheh Alavi
Dental Medicine Faculty Research
Aim To compare efficacy of an anhydrous 0.454% w/w stannous fluoride/sodium fluoride toothpaste (Test) versus a sodium monofluorophosphate toothpaste (Negative control) and a stannous chloride/sodium fluoride toothpaste (Positive control) for dentine hypersensitivity relief after 8 weeks’ twice-daily use. Materials and Methods In this randomized, examiner-blind, stratified, parallel study, primary and secondary efficacy variables were mean changes in Schiff score (evaporative [air] sensitivity) and tactile threshold (Yeaple probe), respectively, from baseline to Week 8 between Test (n = 62) and Negative control (n = 62). Test and Positive control (n = 61) comparisons were exploratory objectives. Results All groups significantly improved …
Factors Associated With Preventable Emergency Department Visits For Nontraumatic Dental Conditions In The U.S., Pearl C. Kim, Wenlian Zhou, Shawn J. Mccoy, Ian K. Mcdonough, Betty Burston, Marcia Ditmyer, Jay J. Shen
Factors Associated With Preventable Emergency Department Visits For Nontraumatic Dental Conditions In The U.S., Pearl C. Kim, Wenlian Zhou, Shawn J. Mccoy, Ian K. Mcdonough, Betty Burston, Marcia Ditmyer, Jay J. Shen
Dental Medicine Faculty Research
This study was designed to examine national trends and evaluate social determinants of health that were associated with the provision of dental services in emergency rooms in the United States between 2007 and 2014. A pooled cross-sectional database of emergency department (ED) visits combined the 2007–2014 waves of the Nationwide Emergency Department Sample. A total of 3,761,958 ED visits with dental conditions were extracted and the principal diagnosis was identified. A series of modified Poisson regression models were used to assess the relationship between patient sociodemographic factors and hospital characteristics, and the likelihood of visiting the ED for a nontraumatic …