Dentistry Commons^™

Development And Validation Of A Rule-Based Algorithm To Identify Periodontal Diagnosis Using Structured Electronic Health Record Data, Bunmi Tokede, Ryan Brandon, Chun-Teh Lee, Guo-Hao Lin, Joel White, Alfa Yansane, Xiaoqian Jiang, Elsbeth Kalenderian, Muhammad Walji

Student and Faculty Publications

AIM: To develop and validate an automated electronic health record (EHR)-based algorithm to suggest a periodontal diagnosis based on the 2017 World Workshop on the Classification of Periodontal Diseases and Conditions.

MATERIALS AND METHODS: Using material published from the 2017 World Workshop, a tool was iteratively developed to suggest a periodontal diagnosis based on clinical data within the EHR. Pertinent clinical data included clinical attachment level (CAL), gingival margin to cemento-enamel junction distance, probing depth, furcation involvement (if present) and mobility. Chart reviews were conducted to confirm the algorithm's ability to accurately extract clinical data from the EHR, and then …

10-Minute Ebd: Is Oil-Pulling Useful In Treating Periodontal Disease?, Heather Willey Rda

The Journal of the Michigan Dental Association

The 10-Minute Evidence-Based Dentistry Column illustrates how to implement the evidence-based dentistry search process to quickly identify and apply the best literature to answer a clinical question. Through critical appraisal, the author of this article answers the clinical question: Is Oil-Pulling Useful in Treating Periodontal Disease? Examining the potential utility of oil-pulling as a treatment for periodontal disease and comparing it to conventional periodontal therapies. The study conducted an evidence-based search using various databases and keywords related to oil-pulling, periodontal disease, and oral health. The results revealed that oil-pulling is not a substitute for standard oral hygiene practices, and insufficient …

Commentary: Phytocannabinoids As Therapeutic Agents To Combat Chronic Gingival Disease., Nick Narek Ohanian

Pacific Journal of Health

The therapeutic potential of cannabis has been harnessed for thousands of years yet the United States Food and Drug Administration (FDA) has still not approved cannabis as a safe or effective drug. The FDA has, however, approved the manufacturing of pharmaceutical drugs, which contain a “synthetic version of a substance that is present in the marijuana” and other compounds that mimic its action. A search of the US National Library of Medicine and National Institute of Health for keywords “CBD” and “Periodontitis” together yields only 2 publications. Although the current State and Federal regulations on the use of cannabis for …

Probiotic Biotherapy: Discussing Its Influential Role In Oral Health, Karla Florez, Claudette Sullano

Dental Hygiene Student Scholarship

Introduction: Probiotics are widely known for their health promoting benefits, especially with its association to gastrointestinal health. For many years, most research has been focused on the prevention or treatment of gastrointestinal infections or diseases. However, recently probiotics has been a subject of investigation with its association to oral health. This review of literature is designed to analyze the effectiveness of using probiotics as a preventative and therapeutic method for oral infections/diseases such as periodontitis, dental caries, and the like.

Methods: Databases such as the PubMed, and Google Scholar were utilized to find current and relevant findings for this …

Systemic Th17 Response In The Presence Of Periodontal Inflammation, Lina J Suárez, Daniel E Vargas, Adriana Rodríguez, Roger M Arce, Nelly S Roa

Student and Faculty Publications

BACKGROUND: The relationship between periodontitis and the pathogenesis of other inflammatory diseases, such as diabetes, rheumatoid arthritis and obesity has been an important topic of study in recent decades. The Th17 pathway plays a significant role in how local inflammation can influence systemic inflammation in the absence of systemic pathology.

OBJECTIVE: To determine Th17 biased-cells in systemically healthy patients in the presence of generalized chronic periodontitis.

METHODOLOGY: A total of 28 patients were recruited without systemic inflammatory pathology, which was determined by clinical history, the Health Assessment Questionnaire (HAQ) and rheumatoid factor detection. Of these patients, 13 were diagnosed as …

Comparison Of Power Versus Manual Toothbrush In Reducing Gingivitis, Keerthi Kamreddy

Master's Theses (2009 -)

The purpose of the present 4-week, parallel-arm, single-blinded, clinical study is to investigate the efficacy and safety of a new power toothbrush in comparison with a standard flat trim ADA approved manual brush. The primary objective of this study is to evaluate the efficacy of powered toothbrush on gingivitis reduction compared to a manual toothbrush. Secondary objectives of this study are to evaluate the effectiveness of plaque removal.Materials & Methods: The study was a single-blinded parallel arm randomized controlled interventional trial. Forty-six male and female subjects with gingivitis (32 female and 16 males) with a mean age of 26 …

Comparative Analysis Of Microbial Sensing Molecules In Mucosal Tissues With Aging, Octavio A. Gonzalez, Sreenatha S. Kirakodu, Michael John Novak, A. J. Stromberg, L. Orraca, J. Gonzalez-Martinez, A. Burgos, Jeffrey L. Ebersole

Center for Oral Health Research Faculty Publications

Host-bacterial interactions at mucosal surfaces require recognition of the bacteria by host cells enabling targeted responses to maintain tissue homeostasis. It is now well recognized that an array of host-derived pattern recognition receptors (PRRs), both cell-bound and soluble, are critical to innate immune engagement of microbes via microbial-associated molecular patterns (MAMP). This report describes the use of a nonhuman primate model to evaluate changes in the expression of these sensing molecules related to aging in healthy gingival tissues. Macaca mulatta aged 3-24 years were evaluated clinically and gingival tissues obtained, RNA isolated and microarray analysis conducted for gene expression of …

Cross-Talk Between Clinical And Host-Response Parameters Of Periodontitis In Smokers, Radha Nagarajan, Craig S. Miller, Dolph R. Dawson Iii, Mohanad Al-Sabbagh, Jeffrey L. Ebersole

Institute for Biomedical Informatics Faculty Publications

Background and Objective

Periodontal diseases are a major public health concern leading to tooth loss and have also been shown to be associated with several chronic systemic diseases. Smoking is a major risk factor for the development of numerous systemic diseases, as well as periodontitis. While it is clear that smokers have a significantly enhanced risk for developing periodontitis leading to tooth loss, the population varies regarding susceptibility to disease associated with smoking. This investigation focused on identifying differences in four broad sets of variables, consisting of: (i) host‐response molecules; (ii) periodontal clinical parameters; (iii) antibody responses to periodontal pathogens …

Targeted Salivary Biomarkers For Discrimination Of Periodontal Health And Disease(S), Jeffrey L. Ebersole, Radhakrishnan Nagarajan, David Akers, Craig S. Miller

Center for Oral Health Research Faculty Publications

Generally, clinical parameters are used in dental practice for periodontal disease, yet several drawbacks exist with the clinical standards for addressing the needs of the public at large in determining the current status/progression of the disease, and requiring a significant amount of damage before these parameters can document disease. Therefore, a quick, easy and reliable method of assessing and monitoring periodontal disease should provide important diagnostic information that improves and speeds treatment decisions and moves the field closer to individualized point-of-care diagnostics.

OBJECTIVE: This report provides results for a saliva-based diagnostic approach for periodontal health and disease based upon …

The Anti-Plaque Efficacy Of Listerine® Used In Combination With Toothbrushing In Orthodontic Patients, Zachary A. Casagrande

Theses and Dissertations

The bactericidal efficacy of Listerine®, the essential oil-containing mouthrinse, has long been recognized. The purpose of this study was to determine whether Listerine® mouthrinse, when added to the standard oral hygiene regimen, had an added benefit in reducing plaque and gingivitis development in orthodontic patients over a six-month period. 50 orthodontic patients from the Virginia Commonwealth University Department of Orthodontics were assigned either to the brushing + flossing (N= 25) or brushing + flossing + Listerine® (N = 25) group. At baseline (TI), measurements for the Ramfjord teeth were recorded for the gingival index, plaque index and bleeding index. Subsequent …

The Comparative Effects Of 0.12% Chlorhexidine And Herbal Oral Rinse On Dental Plaque-Induced Gingivitis, Elizabeth N. Southern, Gayle B. Mccombs, S. L. Tolle, Ken Marinak

Dental Hygiene Faculty Publications

PURPOSE: The purpose of this study was to determine the effects of two oral rinses-one 0.12% chlorhexidine rinse (CHX) and one herbal rinse (HBR)-on gingival health status over time.

METHODS: Sixty-three participants were randomly assigned to one of three treatment groups: CHX, HBR, or placebo. For three months, participants rinsed twice daily (morning and evening) with (1/2) ounce of allocated rinse after brushing and flossing. Individuals were given the same type of soft bristle toothbrush and whitening toothpaste. No attempt was made to modify participants' routine oral care, except they were advised to refrain from use of any other oral …

Sulcular Sulfide Monitoring: An Indicator Of Early Dental Plaque-Induced Gingival Disease, Aleksandra Pavolotskaya, Gayle Mccombs, Michele Darby, Kenneth Marinak, Naik N. Dayanand

Dental Hygiene Faculty Publications

Purpose. The purpose of this study was to evaluate the relationship between volatile sulfur compounds (VSC) and gingival health status and to determine if volatile sulfur compounds can detect early dental plaque-induced gingival disease. Methods. A split-mouth design with randomly selected quadrants of the mandibular arch enabled 39 participants to serve as their own controls. At baseline and at three subsequent appointments (days 7, 14, and 21) gingival inflammation (GI), bleeding on probing (BOP), and sulfide levels (SUL) were measured using the Gingival Index and the Diamond Probe/Perio 2000 System. For three weeks, participants refrained from brushing and flossing one …

The Comparative Effects Of 0.12% Chlorhexidine And An Herbal Oral Rinse On Dental Plaque-Induced Gingivitis, Elizabeth N. Southern

Dental Hygiene Theses & Dissertations

The purpose of this study was to determine the effects of 0.12% chlorhexidine rinse (CID{) and herbal rinse (HBR) to placebo, on gingival health status over time. Methods: 63 subjects (57% male, 43% female, mean age 25 years, sd=7.67) were randomly assigned to one of three treatment groups; CHX, HBR, or placebo. Subjects rinsed twice daily (AM and PM) with ½ ounce of allocated rinse, after brushing and flossing, for three months. Subjects were given the same type of soft bristle toothbrush and whitening toothpaste. Participants were advised to refrain from use of any other oral rinse for the duration …

Sulphur By-Product: A Potential Indicator Of Early Dental Plaque-Induced Gingival Disease Activity: A Pilot Study, Hui Zhou

Dental Hygiene Theses & Dissertations

The purpose of this study was to determine the relationship between volatile sulfide compounds and gingival health status, and to identify if volatile sulfide compounds can detect early dental plaque-induced gingival disease, using an experimental gingivitis model. The sample consisted of 12 subjects between 19 and 28 years, with a healthy gingival status. A split-mouth design utilizing only the mandibular arch was used. A baseline full-mouth periodontal probing status was measured. After baseline data collection and for two weeks, subjects refrained from brushing and flossing one randomly selected half of the mandibular arch. At baseline and six subsequent appointments, gingival …

Mycoplasmas In Plaque And Saliva Of Children And Their Relationship To Gingivitis, Holt R. D., Wilson M., Musa S.

Sabri Musa

GINGIVITIS IS COMMON IN CHILDREN but its etiology is not well understood. Results of earlier studies have suggested that mycoplasmas may have a role in the disease. In this study two plaque samples and one stimulated saliva sample were taken from each of a group of sixty (60) 5 to 9 year-old children and cultured selectively for mycoplasmas. Subjects had been selected on the basis of gingival status buccal to the most posterior tooth in an upper quadrant, 20 each having scores 0, 1, or 2 at this site using the Loe and Silness index. Plaque samples were taken from …

Clinical Effects Of Daily Rotary Electric Toothbrushing On The Presence Of Gingivitis And Supragingival Dental Plaque, Laura Jean Mueller

Dental Hygiene Theses & Dissertations

The purpose of this investigation was to determine if statistically significant differences existed in the gingival health of subjects who brushed with a rotary electric toothbrush (Rota-dent^R when compared to a conventional toothbrush (Oral B-35^R). A randomized, two group research design was employed using forty subjects. At baseline and at two week intervals for six weeks, gingivitis and supragingival dental plaque were measured by the Loe and Silness Gingival Index and the O'Leary Plaque Index, respectively. Multivariate analysis revealed that the Rota-dent^R was superior to the conventional toothbrush in reducing dental plaque accumulation and equally effective …

Clinical Effectiveness Of ListerineR And ViadentR Mouthrinses On Bacterial Plaque And Gingivitis, Debra Pizzola Powell

Dental Hygiene Theses & Dissertations

The purpose of this investigation was to determine the effects of two commercial mouth rinses, Listerine^R and Viadent^R, on bacterial plaque and gingivitis. over a sixweek period, 24 adults, ages 18-41, were examined for the amount of bacterial plaque and level of gingivitis using Silness and toe's Plaque Index (PLI) and Gingival Index (GI). At the beginning of each two week period, subjects were examined for the amount of plaque and level of gingivitis and given a different mouthrinse: appointment one--viadent^R (mouthrinse A), appointment two--placebo mouthrinse (mouthrinse B), and appointment three--Listerine^R (mouthrinse C). Additionally, subjects …

Ask Yourself (1975), American Dental Association, American Academy Of Periodontology

Patient Dental Health Education Brochures

No abstract provided.

Ask Yourself (1967), American Dental Association, American Academy Of Periodontology

Patient Dental Health Education Brochures

No abstract provided.

Don't Let This Happen To You (1959), American Dental Association

Patient Dental Health Education Brochures

No abstract provided.