Dentistry Commons^™

Proteoglycans In Mechanobiology Of Tissues And Organs: Normal Functions And Mechanopathology, Mary C Farach-Carson, Danielle Wu, Cristiane Miranda França

Faculty, Staff and Student Publications

Proteoglycans (PGs) are a diverse class of glycoconjugates that serve critical functions in normal mechanobiology and mechanopathology. Both the protein cores and attached glycosaminoglycan (GAG) chains function in mechanically-sensitive processes, and loss of either can contribute to development of pathological conditions. PGs function as key components of the extracellular matrix (ECM) where they can serve as mechanosensors in mechanosensitive tissues including bone, cartilage, tendon, blood vessels and soft organs. The mechanical properties of these tissues depend on the presence and function of PGs, which play important roles in tissue elasticity, osmolarity and pressure sensing, and response to physical activity. Tissue …

Is Preexisting Inflamed Jaw Marrow A “Hidden” Co-Morbidity Affecting Outcomes Of Covid-19 Infections? – Clinical Comparative Study, Johann Lechner, Robert E Mcmahon, Jerry E Bouquot, Florian Notter, Fabian Schick

Faculty, Staff and Student Publications

Introduction: Exceedingly high levels of the chemokine CCL5/RANTES have been found in fatty degenerated osteonecrotic alveolar bone cavities (FDOJ) and aseptic ischemic osteolysis of the jaw (AIOJ) from toothless regions. Because CCL5/RANTES seems to have a prominent role in creating the COVID-19 “cytokine storm”, some researchers have used the monoclonal antibody Leronlimab to block the CCR5 on inflammatory cells.

Objective: Is preexisting FDOJ/AIOJ jaw marrow pathology a “hidden” co-morbidity affecting some COVID-19 infections? To what extent does the chronic CCL5/RANTES expression from preexisting FDOJ/AIOJ areas contribute to the progression of the acute cytokine storm in COVID-19 patients?

Methods: Authors report …

N Y State Dent J January 2024

The New York State Dental Journal

In the January 2024 issue, the reader will find the following feature articles:

• When One Door Closes, Another Opens
• Oral Manifestations of Metastatic Diseases: A Clinical and Histologic Analysis of Seven Cases
• Dentistry Transformed: An Overview of Artificial Intelligence’s Role in Dental Care
• Unlocking the Future of Dentistry: A Summary of AI and Augmented Intelligence in Dentistry from ADA’s White Paper
• Diagnostic Detail: Understanding the Impact of Tooth Rotation in Correcting Mucogingival Defects

This issue includes regular columns with regional news impacting the New York membership including: editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and …

J Mich Dent Assoc January 2024

The Journal of the Michigan Dental Association

Every month, The Journal of the Michigan Dental Association brings news, information, and features about Michigan dentistry to our state's oral health community and the MDA's 6,200+ members. No publication reaches more Michigan dentists!

The January issue sets the foundation for Children’s Dental Health Month in February, the reader will find the following original content:

• A cover commentary on Pediatric Dentistry
• A feature article on “Silver Diamine Fluoride as a Caries Management Option for the Young Child”.
• A feature on “Considerations Concerning Obesity-Related Education for Parents of Young Children”.
• Professional advice commentary on “Staying Focused on a Moving Target: Coping …

Mda Foundation: 2024 Promises Great Things From The Mda Foundation, Anne Berquist

The Journal of the Michigan Dental Association

The MDA Foundation is making significant strides in supporting dental and hygiene students and the community. In a recent announcement, 12 scholarships totaling $31,000 were awarded, thanks to donor generosity. The Foundation's upcoming Sparkling Smiles Celebration will provide an opportunity to meet scholarship recipients and acknowledge donors. The primary focus in June will be the Mission of Mercy event in Flint, aiming to offer essential dental care to up to 2,000 individuals. Volunteers are encouraged to participate, and financial support can be pledged online. Ongoing efforts include fundraising for the Karen Burgess Scholarship Endowment and the upcoming MDA Foundation golf …

Crown Fatigue Resistance And Enamel Wear Of 3d Printed Resin Compared To Lithium Disilicate, Pranit Vasant Bora

All ETDs from UAB

Purpose: The purpose of this study is to compare the wear characteristics and fatigue resistance of two dental crown materials: SprintRay Ceramic Crown, a 3D-printed resin material, and IPS™ e.Max CAD, a lithium disilicate material. Methods: This study evaluates wear and fatigue characteristics of dental crowns made from Ceramic Crown (SprintRay) and IPS e.max CAD LT (Ivoclar). For fatigue testing, custom fatigue devices were utilized to subject the crowns to cyclic loading, simulating occlusal forces. The specimens underwent 100,000 cycle intervals until 1.5 million cycles at a load of 40N of fatigue loading, with inspections conducted for signs of debonding, …

Effect Bioactive Material Have On Tooth Demineralization, Taillk Gomes

All ETDs from UAB

The objective of this in vitro study is to compare the inhibition of demineralization of root dentin caused by the presence of different restorative materials using Vickers Hardness (HV) test (microhardness) test and polarized light microscopy (PLM).

Immunohistochemical Analysis Of Dentigerous Cysts And Odontogenic Keratocysts Associated With Impacted Third Molars—A Systematic Review, Luis Eduardo Almeida, David Lloyd, Daniel Boettcher, Olivia Kraft, Samuel Zammuto

School of Dentistry Faculty Research and Publications

Objective: This systematic review investigates the diagnostic, prognostic, and therapeutic implications of immunohistochemical markers in dentigerous cysts (DCs) and odontogenic keratocysts (OKCs) associated with impacted third molars.

Materials and Methods: A comprehensive search strategy was employed across major databases including MEDLINE/PubMed, EMBASE, and Web of Science, from the inception of the databases to March 2024. Keywords and Medical Subject Heading (MeSH) terms such as “dentigerous cysts”, “odontogenic keratocysts”, “immunohistochemistry”, “Ki-67”, and “p53” were used. The PRISMA 2020 guidelines were followed to ensure methodological rigor. Inclusion criteria encompassed studies on humans and animals providing definitive diagnoses or specific signs and symptoms …

The Impact Of Aging And Storage Conditions On The Performance Of Universal Adhesives: A Systematic Review, Maryam Ghamgosar, Mehrsima Ghavami-Lahiji, Sanaz Mihandoust, Enayatollah Homaie Rad, Hassan Salehipour Masooleh, Lobat Tayebi

Electrical & Computer Engineering Faculty Publications

Objective: This systematic review evaluated how different storage times and conditions affect universal adhesives' bond strength and degree of conversion (DC).

Methods: A literature search was conducted in PubMed, Scopus, Web of Science, and Google Scholar databases for articles published from January 1st, 2000, until May 15th, 2022. The researchers comprehensively evaluated the articles using a multi-step process to identify articles relevant to the topic of interest. Quality assessment was performed through the ROBDEMAT tool. Due to the high heterogeneity in the preliminary data, performing a meta-analysis was not feasible.

Results: A total of 3169 records were obtained, and after …

Orthodontically Induced Changes To The Genetic Profile In Periodontal Ligament Tissue And Cytokine Release In Gingival Crevicular Fluid – A Pilot Investigation, Nutthakarn Ratanasereeprasert, Li-Fang Hsu, Shih-Kai Wang, Chung-Chen Jane Yao

Faculty, Staff and Student Publications

BACKGROUND/PURPOSE: It has been known that genetic factors influence orthodontic tooth movement, however, scientific research on humans is lacking. Therefore, this study aimed to investigate dynamic changes to the genetic profile in human periodontal ligament (PDL) tissue and cytokine release in gingival crevicular fluid (GCF) during the first 28 days of orthodontic treatment.

MATERIALS AND METHODS: Fifteen teeth from three patients were recruited. Full-mouth fixed appliances with extraction of four premolars and one maxillary third molar was planned for orthodontic treatment. GCF collection and tooth extraction were performed following force application for 0, 1, 3, 7, and 28 days. GCF …

A Novel Odaph Mutation Causing Amelogenesis Imperfecta And Its Expression In Human Dental Tissues, Shih-Kai Wang, Zhe-Hao Lee, Parissa Aref, Kuan-Yu Chu

Faculty, Staff and Student Publications

BACKGROUND/PURPOSE: Amelogenesis imperfecta (AI), an assemblage of genetic diseases with dental enamel malformations, is generally grouped into hypoplastic, hypomaturation, and hypocalcified types. This study aimed to identify the genetic etiology for a consanguineous Iranian family with autosomal recessive hypocalcified AI.

MATERIALS AND METHODS: Dental defects were characterized, and whole exome analysis conducted to search for disease-causing mutations. Minigene assay and RT-PCR were performed to evaluate molecular consequences of the identified mutation and expression of the causative gene in human dental tissues.

RESULTS: The defective enamel of erupted teeth showed extensive post-eruptive failure and discoloration. Partial enamel hypoplasia and indistinct dentino-enamel …

A Novel Collaborative Learning Model For Mixed Dentition And Fillings Segmentation In Panoramic Radiographs., Erin Ealba Bumann, Saeed Al-Qarni, Geetha Chandrashekar, Roya Sabzian, Brenda S Bohaty, Yugyung Lee

Manuscripts, Articles, Book Chapters and Other Papers

INTRODUCTION: It is critical for dentists to identify and differentiate primary and permanent teeth, fillings, dental restorations and areas with pathological findings when reviewing dental radiographs to ensure that an accurate diagnosis is made and the optimal treatment can be planned. Unfortunately, dental radiographs are sometimes read incorrectly due to human error or low-quality images. While secondary or group review can help catch errors, many dentists work in practice alone and/or do not have time to review all of their patients' radiographs with another dentist. Artificial intelligence may facilitate the accurate interpretation of radiographs. To help support the review of …

The Effect Of Systemic Antibiotics On Post-Surgical Complications And Patient-Reported Outcomes In Dental Implant Surgery With Simultaneous Sinus Floor Augmentation, Sutinee Tangamnuay

Chulalongkorn University Theses and Dissertations (Chula ETD)

Unnecessary antibiotic prescriptions can raise healthcare costs and affect the quality of life due to their related side effects. Objectives: Aim to assess the impact of antibiotic prophylaxis (AP) on the prevalence of postoperative complications in patients undergoing simultaneous implant placement with lateral sinus floor augmentation. Materials and Methods: A randomized, triple-blind, placebo-controlled trial was conducted involving 30 healthy patients. Participants were divided into two groups: one received 2g of amoxicillin before surgery and 500mg three times daily for three days post-surgery (antibiotic group, N=15), while the other received a placebo (N=15). Postoperative complications were evaluated at 2, 4, and …

The Influence Of Implant Thread Designs On The Secondary Stability Of Dental Implant, Rujira Charoenniwassakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objective: This study aimed to evaluate the secondary stability of aggressive thread design implant (BLX) comparing to nonaggressive thread design implant (BL) using Implant Stability Quotient (ISQ) values and Implant stability test (IST) values. Materials and Methods: Forty-five patients with healed edentulous areas were included and randomly allocated into test and control groups. Thirty-two BLX implants and thirty-two BL implants were used in the test and control groups, respectively. Dental implant stability was assessed using IST and ISQ values. IST values were measured immediately (T1), on day 2 (T2), and at 1 (T3), 2 (T4), 3 (T5), 4 (T6), 5 …

การศึกษาการสึกระหว่างโคบอลต์โครเมียมและวัสดุเซรามิกที่ใช้ในงานทันตกรรมดิจิตอล, มรกต ไทยรัตน์

Chulalongkorn University Theses and Dissertations (Chula ETD)

วัตถุประสงค์: ทำการศึกษาสภาวะจำลองเพื่อวัดการสูญเสียปริมาตรจากการสึกหลังจากจำลองการขัดถู 250,000 รอบของโลหะผสมโคบอลต์โครเมียม (CoCr) กับวัสดุที่ใช้ทำการบูรณะฟันหลักห้าชนิด วัสดุและวิธีการ: เตรียมตัวอย่างทดสอบตัดเป็นสี่เหลี่ยมจำนวนชนิดละ 8 ชิ้น (5 x 5 x 2 มิลลิเมตร) จากโลหะผสมที่ไม่มีทองผสม (NP), ลิเธียมไดซิลิเกต (EM) เธียมไดซิลิเกตเสริมความแข็งแรง (TR) เซรามิคที่มีเรซินเป็นฐาน (CM) และเซอร์โคเนีย (ZR) ตัวอย่าง EM TR และ ZR ได้รับการเผาตามคำแนะนำของผู้ผลิต แท่งโลหะผสมโคบอลต์โครเมียมสร้างขึ้นโดยการหล่อโลหะแบบไล่ขี้ผึ้ง จำลองการสึกแบบสององค์ประกอบด้วยเครื่องจำลองการสึกจากการขัดถู จำนวน 250,000 รอบ วัดการสูญเสียปริมาตรของชิ้นงานทดสอบโดยใช้เครื่องวัดความหยาบพื้นผิว การสูญเสียปริมาตรของแท่งโลหะผสมคำนวณโดยการความยาวที่ลดลงและรัศมีของพื้นที่ที่เกิดบริเวณที่สึก วิเคราะห์ข้อมูลทางสถิติโดยใช้ MANOVA (pNP>ZR) การสูญเสียปริมาตรของแท่งโลหะหลังการสึกในกลุ่ม CM น้อยกว่าในกลุ่ม EM และ NP ในขณะที่กลุ่มอื่น ๆ ไม่มีความแตกต่างกันอย่างมีนัยสำคัญ

Needs Assessment For Sexual Violence Trauma-Informed Care In The Dental Field, Joshua Garufi

Antioch University Dissertations & Theses

Trauma-informed care provides a framework for health care providers to more effectively treat their patients who have a history of trauma (Hamberger et al., 2019). Upon reviewing the literature, there is a paucity of research on trauma-informed care in the dental field. This research performed a needs assessment to determine if trauma-informed care is being implemented into the curriculum at a specific dental school, SUNY Buffalo. This research also inquired about residential dentist and faculty attitudes toward trauma-informed care being implemented in the dental field. Two short, original surveys were administered to residential dentists who recently graduated from the University …

Comparison Of Dmft And Behavior Rating Scores Between Children With Systemic Disease And Healthy Children At The First Dental Visit, Gizem Erbaş Ünverdi, Beste Ozgur, H. Cem Güngör, Paul S. Casamassimo

School of Dentistry Faculty Research and Publications

Purpose: To evaluate and compare oral health and behavior scores at the first dental visit and dental treatment need using general anesthesia/sedation (GA/S) of children with systemic diseases (SD) and healthy children.

Methods: Data were obtained from healthy children (n = 87) and children with SD (n = 79), aged 4 to 6 years, presenting to a hospital dental clinic for a first dental examination. The total number of decayed, missing and filled teeth (dmft), dental behavior score using Frankl Scale, and dental treatment need using GA/S were recorded. Chi-square / Fisher’s exact test and Mann–Whitney U …

Exploring And Describing Current Behavioral And Social Sciences Curricula In Predoctoral Dental Programs, Casey D. Wright, Lance Brendan Young

School of Dentistry Faculty Research and Publications

Purpose

To maintain accreditation status, predoctoral dental programs in the United States and Canada are required to train future dentists in the fundamentals of behavioral sciences. Each program independently determines how to fulfill this task, and little information exists on the consistency of training across programs. The purpose of this study was to identify the range of topics currently taught in predoctoral dental programs in the United States and Canada, who teaches them, and the modes of instruction and assessment.

Methods

Invitations to complete an online survey were emailed to faculty responsible for, or familiar with, the behavioral sciences curricula …

Evaluating Surgical Approaches For Hemimandibular Hyperplasia Associated With Osteochondroma: A Systematic Literature Review, Luis Eduardo Almeida, Samuel Zammuto, Diego Fernando Lopez

School of Dentistry Faculty Research and Publications

Background/Objectives: Hemimandibular hyperplasia (HH) associated with osteochondroma presents complex challenges in maxillofacial surgery, including facial asymmetry, occlusal instability, and temporomandibular joint (TMJ) dysfunction. Surgical interventions vary widely in approach and outcomes, underscoring the need for a systematic evaluation of effectiveness. This systematic review assesses the effectiveness of surgical approaches for managing HH associated with osteochondroma, focusing on techniques including condylectomy, orthognathic surgery, distraction osteogenesis, total joint replacement (TJR), and genioplasty. Methods: Following PRISMA 2020 guidelines, a comprehensive search was conducted in PubMed, Scopus, and Web of Science for studies published from 2000 to 2023. Eligibility criteria were based on the …

Bayesian Rare Variant Analysis Identifies Novel Schizophrenia Putative Risk Genes, Shengtong Han

School of Dentistry Faculty Research and Publications

The genetics of schizophrenia is so complex that it involves both common variants and rare variants. Rare variant association studies of schizophrenia are challenging because statistical methods for rare variant analysis are under-powered due to the rarity of rare variants. The recent Schizophrenia Exome meta-analysis (SCHEMA) consortium, the largest consortium in this field to date, has successfully identified 10 schizophrenia risk genes from ultra-rare variants by burden test, while more risk genes remain to be discovered by more powerful rare variant association test methods. In this study, we use a recently developed Bayesian rare variant association method that is powerful …

Association Between Periodontal Health Status And Quality Of Life: A Cross-Sectional Study, Kinan M. Al-Bitar, Jeffery M. Garcia, Shengtong Han, Arndt Guentsch

School of Dentistry Faculty Research and Publications

Introduction: Attachment loss due to periodontal diseases is associated with functional limitations as well as physical pain and psychological discomfort, which may lead to a reduced quality of life. The purpose of this study is to determine if the oral health status, specifically the periodontal status, influences oral health–related quality of life.

Materials and methods: Survey data were collected in a US dental school clinical setting in a cross-sectional study. Quality of life related to oral health was assessed with the Oral Health Impact Profile-49 (OHIP-49). In addition, DMFT index, periodontal status, and health literacy scores (dental and medical health …

Comparison Between Coronally Advanced Flap With Sub-Epithelial Connective Tissue Graft And Tunnel Technique With Sub-Epithelial Connective Tissue Graft In Achieving Mean Root Coverage At Multiple Recession Defects: A Retrospective Study, Christian Daniel Davila

Graduate Theses, Dissertations, and Problem Reports (ETD)

Aim: The primary objective is to retrospectively compare the mean root coverage (MRC) achieved using a coronally advanced flap and sub-epithelial connective tissue graft (CAF + CTG) with that achieved using the tunnelling technique and sub-epithelial connective tissue graft (TUN + CTG) for the treatment of multiple recession defects. The secondary objectives are to compare the proportion of complete root coverage (CRC) achieved with CAF + CTG compared to TUN + CTG, compare the proportion of CRC achieved in these two techniques with respect to level of training (American board-certified periodontist or Graduate periodontics residents) and to evaluate the …

Influence Of Scaling And Root Planing With Minocycline Microspheres On Clinical Outcomes Of Patients With Periodontitis, Nupoor Sandeep Kulkarni

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Scaling and root planning (SRP) has been established as a “gold-standard” non-surgical initial treatment for periodontitis. Along with SRP, some systemic adjuncts like systemic antibiotics were used in the past to gain maximum benefits of SRP by reducing the need for further periodontal surgeries. Due to some drawbacks of systemic antibiotic use, like “transient antibiotic resistance”, “non-adherence” and “insufficient concentrations in the periodontal pockets to be clinically effective”, there was a shift towards the use of local antibiotic adjuncts to SRP like minocycline, tetracycline, chlorhexidine etc. Minocycline is a semi-synthetic tetracycline derivative which is available in a powder form, …

Dentin-Sealer Bond Strength. A Review: An In-Vitro Comparison Between Guttaflow 2 ®, Endosequence Bc High Flow ®, Tubli-Seal ®, Sealapex ®, And Ah Plus Jet ® Sealers., Zied Diab

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction: One objective of non-surgical endodontic therapy is the formation of a hermetic seal with elimination of any portal of entry of bacteria and their byproducts into the root canal space from periapical tissue. Extensive research has been conducted to determine ideal endodontic sealers. Bioceramic sealers have risen to prominence due to reported decreased shrinkage, less toxicity, and superior bond strength to root dentin compared to zinc oxide eugenol, calcium hydroxide, and resin-based sealers. GuttaFlow2®, a new sealer on the market, is composed of calcium silicate in combination with gutta-percha particles. Researchers from Coltene (Altstätten, Switzerland), the manufacturer of GuttaFlow2® …

Comparative Cephalometric Study Between Class Ii Patients Treated With Herbst Appliance And Patients Treated With Mara, Mona Meky

Graduate Theses, Dissertations, and Problem Reports (ETD)

ABSTRACT

Comparative cephalometric study between Class II patients treated with Herbst appliance and patients treated with MARA

Mona Meky, D.D.S.

Background and Objectives: Functional appliances have been used for over 100 years in orthodontics to correct Class II malocclusions. The Herbst and the MARA appliances have different designs that may enhance mandibular growth. Recent clinical evidence has questioned whether they really have a lasting influence on facial growth and that the effects of these appliances were mostly dentoalveolar rather than skeletal. The objective of this retrospective comparative study was to compare the dental and skeletal changes between Class II division …