Dentistry Commons^™

Bonding Crowns And Bridges With Resin Cement, Nathaniel C. Lawson, Sharukh Khajotia, Ana K. Bedran-Russo, Kevin Frazier, Jacob Park, Ariene A. Leme-Kraus, Olivia Urquhart

School of Dentistry Faculty Research and Publications

Background

Bonding crowns and bridges with resin cement can improve retention and reinforcement of the restoration. However, there is variation in the steps taken by different practitioners to achieve this goal.

Methods

The authors developed a survey on bonding dental crowns and bridges with resin cement and distributed it electronically to the American Dental Association Clinical Evaluators (ACE) Panel on May 22, 2020. The survey remained open for 2 weeks. Descriptive data analysis was conducted using SAS Version 9.4.

Results

A total of 326 panelists responded to the survey, and 86% of respondents who place crowns or bridges use resin …

Removal Of Water Binding Proteins From Dentin Increases The Adhesion Strength Of Low-Hydrophilicity Dental Resins, Ana Paula Farina, Doglas Cecchin, Cristina M. P. Vidal, Ariene A. Leme-Kraus, Ana K. Bedran-Russo

School of Dentistry Faculty Research and Publications

Objectives

To investigate the role of proteoglycans (PGs) on the physical properties of the dentin matrix and the bond strength of methacrylate resins with varying hydrophilicities.

Methods

Dentin were obtained from crowns of human molars. Enzymatic removal of PGs followed a standard protocol using 1 mg/mL trypsin (Try) for 24 h. Controls were incubated in ammonium bicarbonate buffer. Removal of PGs was assessed by visualization of glycosaminoglycan chains (GAGs) in dentin under transmission electron microscopy (TEM). The dentin matrix swelling ratio was estimated using fully demineralized dentin. Dentin wettability was assessed on wet, dry and re-wetted dentin surfaces through water …

Fibroblast Encapsulation In Gelatin Methacryloyl (Gelma) Versus Collagen Hydrogel As Substrates For Oral Mucosa Tissue Engineering, Fahimeh Tabatabaei, Keyvan Moharamzadeh, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Purpose

Over the past decades, a variety of biomaterials have been investigated in terms of their suitability for oral mucosa tissue engineering. The aim of this study was to compare collagen and GelMA hydrogels as connective tissue scaffolds for fibroblasts and as substrates for seeding and culture of oral epithelial keratinocyte cells.

Methods

Human primary oral fibroblast and keratinocyte cells were isolated from gingival biopsies. The mixture of fibroblasts with GelMA or collagen gel were aliquoted within six-well tissue culture plate inserts and cross-linked using visible light or reconstitution buffer/heat, respectively. The viability of fibroblasts in the hydrogels was investigated …

Sublingual Emphysema Following Alveoloplasty: A Case Report, Austin Dodge, Katelyn Kreh, Vrisiis Kofina, Swati Y. Rawal

School of Dentistry Faculty Research and Publications

Various cases of introduction of air into soft tissues have been reported in the dental literature. Here, we report a rare case of localized sublingual emphysema after alveoloplasty. There was no facial involvement. The patient responded to treatment and recovered uneventfully.

Carbosilane Dendrimers: Drug And Gene Delivery Applications, Navid Rabiee, Shokooh Ahmadvand, Sepideh Ahmadi, Yousef Fatahi, Rassoul Dinarvand, Mojtaba Bagherzadeh, Mohammad Rabiee, Mohammadreza Tahriri, Lobat Tayebi, Michael R. Hamblin

School of Dentistry Faculty Research and Publications

Carbosilane dendrimers are a particular type of dendrimer structure that has been used as delivery vehicles for drugs and nucleic acids. They have a defined structure according to their generation number, and their terminal groups can be rendered cationic or anionic. The cationic charges can address the limitation of electrostatic repulsion between the negatively charged phosphate groups of nucleic acids and negatively charged cell membranes. Specific drugs can be loaded into the central part of the dendrimer or attached at the exterior, and the overall positive charge may improve the efficacy of anti-inflammatory drugs. One promising feature of dendrimers is …

Three-Dimensional In Vitro Oral Mucosa Models Of Fungal And Bacterial Infections, Fahimeh Tabatabaei, Keyvan Moharamzadeh, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Oral mucosa is the target tissue for many microorganisms involved in periodontitis and other infectious diseases affecting the oral cavity. Three-dimensional (3D) in vitro and ex vivo oral mucosa equivalents have been used for oral disease modeling and investigation of the mechanisms of oral bacterial and fungal infections. This review was conducted to analyze different studies using 3D oral mucosa models for the evaluation of the interactions of different microorganisms with oral mucosa. In this study, based on our inclusion criteria, 43 articles were selected and analyzed. Different types of 3D oral mucosa models of bacterial and fungal infections were …

Aptamer-Conjugated Plga Nanoparticles For Delivery And Imaging Of Cancer Therapeutic Drugs, Maryam Hashemi, Azarmidokht Shamshiri, Majid Saeedi, Lobat Tayebi, Rezvan Yazdian-Robati

School of Dentistry Faculty Research and Publications

Most problems associated with chemotherapeutic agents involve non-specific cytotoxicity, low intratumoral accumulation and drug resistance. Targeted drug delivery systems (TDDS) based on nanoparticles (NPs) are a new strategy for better therapeutic efficiency, along with reduction of side effects commonly seen with cancer drugs. Poly (lactic-co-glycolic acid) (PLGA), as one of the furthest developed synthetic polymer, has gained significant attention because of excellent properties—including biodegradability and biocompatibility, controlled release of drug, protection of drug or gene from decomposition and ability to modify surface with targeting agents for both cancer diagnosis and therapy. Aptamers are single-stranded RNA or DNA that can fold …

Shedding Light On The Role Of Keratinocyte-Derived Extracellular Vesicles On Skin-Homing Cells, Golara Nasiri, Negar Azarpira, Aliakbar Alizadeh, Sanaz Goshtasbi, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Extracellular vesicles (EVs) are secretory lipid membranes with the ability to regulate cellular functions by exchanging biological components between different cells. Resident skin cells such as keratinocytes, fibroblasts, melanocytes, and inflammatory cells can secrete different types of EVs depending on their biological state. These vesicles can influence the physiological properties and pathological processes of skin, such as pigmentation, cutaneous immunity, and wound healing. Since keratinocytes constitute the majority of skin cells, secreted EVs from these cells may alter the pathophysiological behavior of other skin cells. This paper reviews the contents of keratinocyte-derived EVs and their impact on fibroblasts, melanocytes, and …

Patient And Parent Perceptions On Outcomes In Early Orthodontic Treatment, Joseph Phillips, James Chen

Orthodontics and Endodontics Theses

Introduction: Orthodontics has clinical benefits, however, the psychosocial outcomes are not well understood. These soft benefits are often classified as aesthetic, functional, and psychosocial, however, there is limited work understanding these outcomes as reported directly from the patient. By better understanding the patient’s perspectives, we can continually refine our clinical model to be patient-centric and more appropriately manage the patient’s expectations and experiences. Materials and Methods: This is a cross-sectional qualitative study of 20 parents of 24 children ages 8-11 years. Participants were remotely interviewed using a semi-structured chronologically based line of questioning to elucidate their perceived outcomes of early …

Efficiency And Effectiveness Of Arch Expansion With Corticotomy-Assisted Clear Aligner Therapy, Thomas Roblee, Robert R. Boyd, James Chen, Heesoo Oh

Orthodontics and Endodontics Theses

Introduction: Surgically Facilitated Orthodontic Therapy (SFOT) has been utilized for years to overcome the limitations encountered with traditional orthodontic treatment of dentoalveolar and alveoloskeletal malocclusions. The procedure, which consists of full flap corticotomies and bone grafting, has many proposed benefits including increased speed and range of tooth movement. The purpose of this study is to evaluate arch expansion in patients treated with SFOT and clear aligners. Materials and Methods: A retrospective cohort study design was used to evaluate 51 consecutive adult patients that were treatment planned for significant arch expansion with corticotomies, bone grafting, and clear aligners. 17 of the …

Prevalence Of Short Root Anomaly In Patients Seeking Orthodontic Treatment, Tim Howarth, James Chen, Heesoo Oh

Orthodontics and Endodontics Theses

Introduction: The purpose of this study was to investigate variance in prevalence and severity of short root anomaly (SRA) in patients seeking orthodontic treatment, stratified by ethnicity and sex. Materials and Methods: In this retrospective cross-sectional study, we evaluated 896 patients who had initial cone-beam computed tomographies (CBCTs) taken from July 1, 2014 to May 30, 2019. Panoramic radiographs and images from the CBCTs of each patient were extracted and placed in a database. The crown-to-root ratio of maxillary central incisors, lateral incisors, canines, and all pre-molars were evaluated to determine the presence, severity and associations of SRA. A Chi-square …

Prediction Of Class Iii Treatment Need And Success, Andrew Levin, James Chen

Orthodontics and Endodontics Theses

Objective: The purpose of the present study is to develop prognostic models for surgical need and treatment success for class III malocclusions. Material and Methods: This is a retrospective cohort study that evaluated treatment outcomes of consecutively treated patients at UCSF from Jan 1st 2007-Jan 1st 2012 and UoP from May 1st, 2014 – May 1st 2019. Receiver operator curves were used to develop prognostic models for surgical need and treatment success for class III malocclusions. Predictor variables were selected a priori (Class III-WITS, U1-PP, IMPA). The prognostic models were validated first using a UCSF validation cohort to show consistency …

Invisalign First: A Qualitative Study On The Perceived Benefits And Drawbacks Of Invisalign First As A Treatment Modality For Mixed Dentition Patients, Erin Walker, James Chen

Orthodontics and Endodontics Theses

Given the recent implementation of Invisalign First for early interceptive orthodontic treatment, a limited number of orthodontists have had experience with this treatment modality and there currently are no published studies on the topic. The present study aims to use a qualitative survey to identify common themes in providers’ perceptions of Invisalign First as a new treatment option for early interceptive orthodontics. Twenty-three orthodontists in the private practice sector voluntarily participated in an open-ended survey via email. The results of the survey indicate the following common themes in regards to benefits of Invisalign First: fewer emergencies, patient comfort, patient experience, …

Association Of Type And Severity Of Nonsyndromic Orofacial Clefts With Combined Genotypes Of Rfc1 80 Ga, Mthfr 677 Ct, Irf6 (Rs642961) And Irf6 (Rs2235371) Gene Polymorphisms In An Indian Population, Chantal Hakim Dds, Msd, Marie M. Tolarová Md, Phd, Drsc, Miroslav Tolar Md, Phd

Orthodontics and Endodontics Theses

Association of type and severity of nonsyndromic OROFACIAL CLEFTS with combined genotypes of RFC1 80 GA, MTHFR 677 CT, IRF6 rs642961 and rs2235371 gene polymorphisms in an Indian population Abstract By Chantal Hakim University of the Pacific. Arthur Dugoni School of Dentistry 2020 Introduction. Genetic etiology of nonsyndromic orofacial clefts comprises many genes acting together. However, little is known about their interactions. The purpose of our study was to analyze associations of phenotypic subtypes of nonsyndromic orofacial clefts with combinations of four genotypes involving candidate gene polymorphisms. Materials and Methods. We analyzed a large dataset of cases and controls collected …

Oropharyngeal Airway Changes Following Orthodontic Treatment Of Anterior Open Bite In Growing Vs Non-Growing Patients, Mona Awadi, Heeyeon Suh, Joorok Park, Heesoo Oh

Orthodontics and Endodontics Theses

Introduction: Orthodontic treatment of anterior open bite can result in a counter-clockwise rotation of the mandible and a more ideal forward position of the tongue. Usually this movement is thought to increase the oropharyngeal airway. The primary aim of the present study was to evaluate changes in vertical dimension and airway in AOB patients following orthodontic treatment. Methods: 52 subjects were included in this retrospective study of anterior open bite malocclusion treated in the graduate orthodontics clinic at the University of the Pacific, Arthur A. Dugoni School of Dentistry between 2006 – 2019. Cephalometric and airway measurements were done by …

Soft Tissue Effects From Maxillomandibular Advancement With Counterclockwise Rotation, Timothy Yu, Audrey Yoon, Stanley Yung Chuan Liu, Heeyeon Suh, Joorok Park, Heesoo Oh

Orthodontics and Endodontics Theses

Introduction: The purpose of the study was to evaluate the effects of maxillomandibular advancement (MMA) surgery with counterclockwise rotation on soft tissue oral and nasal structures. Materials and Methods: This retrospective study included 34 subjects diagnosed with OSA who underwent MMA at the Stanford Sleep Clinic. Initial (T1) and Final (T2) CBCTs were evaluated and compared for 10 hard tissue and 15 soft tissue measurements. Additionally, the external nasal valve surface area was measured and compared between the two time points. A 3D superimposition was performed and used to evaluate the relative hard and soft tissue movements. Results: There was …

Comparison Of Skeletal And Dental Differences Between Class I And Class Ii Sides And Their Relationship With Asymmetric Molar Relationships In Class Ii Subdivision Malocclusions – A Cbct Study, Ivan Lo, Heeyeon Suh, Joorok Park, Heesoo Oh

Orthodontics and Endodontics Theses

Introduction: The purpose of this study is to compare dental and skeletal differences between Class I and Class II sides and their contributions to the degree of asymmetric molar relationship in Class II subdivision malocclusions using CBCT.

Methods: One hundred and eight patients presenting with Angle Class II subdivision malocclusions (mean age =21.05 years) were assessed with 3-dimensional cone-beam computed tomography scans. Paired t-tests were used to compare linear skeletal, angular and dental measurement differences between Class I and Class II sides. Correlations of linear skeletal, angular and dental measurement differences between Class I and Class II sides were made …

A Review On The Biodistribution, Pharmacokinetics And Toxicity Of Bismuth-Based Nanomaterials, Samireh Badrigilan, Fatemeh Heydarpanahi, Jalal Choupani, Mehdi Jaymand, Hadi Samadian, Mojtaba Hoseini-Ghahfarokhi, Thomas J. Webster, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Here, bismuth-based nanomaterials (Bi-based NMs) are introduced as promising theranostic agents to enhance image contrast as well as for the therapeutic gain for numerous diseases. However, understanding the interaction of such novel developed nanoparticles (NPs) within a biological environment is a requisite for the translation of any promising agent from the lab bench to the clinic. This interaction delineates the fate of NPs after circulation in the body. In an ideal setting, a nano-based therapeutic agent should be eliminated via the renal clearance pathway, meanwhile it should have specific targeting to a diseased organ to reach an effective dose and …

Epidemiology, Outcome, And Prognostic Factors Of Oropharyngeal Lymphoepithelial Carcinoma: A Population-Based Analysis Using The Seer Database, Serena Lee

Orthodontics and Endodontics Theses

Introduction: Lymphoepithelial carcinoma (LEC) in the oropharynx is rare. Current understanding of the disease is derived mainly from case reports and small case series, prompting further elucidation of its epidemiology and prognostic factors that affect outcome. The aim of this retrospective cohort study was to examine demographic characteristics, clinicopathologic features, and prognostic factors in patients with oropharyngeal LEC. Methods: The U.S. National Cancer Institute’s SEER registry was queried to obtain data on patients with primary oropharyngeal LEC from 1975 to 2016. Variables examined include age at diagnosis, sex, race, year of diagnosis, primary site of tumor origin, tumor size, extent, …

The Effect Of Artificial Aging And Surface Treatments On Microtensile Bond Strength Of Resin Cement To Hybrid Ceramics, Engy I. Hassan Shohdy, Shereen A. Nossair, Amina M. Hamdy

Future Dental Journal

Purpose: To assess the effect of aging and various surface treatments on the microtensile bond strength of resin cement to two hybrid esthetic materials. Materials and Methods: Zirconia-reinforced lithium silicate (Celtra Duo, Dentsply Sirona, United States) and hybrid resin nanoceramic (Cerasmart TM, GC Corporation, Japan) blocks were cut into plates of 3 mm thickness. Each ceramic material was surface treated either with hydrofluoric acid etching and silane or with sandblasting and silane. A dual-cured adhesive resin cement (Panavia TM V5, Kuraray, U.S.A.) was utilized to bond the composite resin plates to the surface treated ceramic plates. The ceramic-composite resin blocks …

Assessment Of Antibacterial Properties And Compressive Strength Of Copaiba Oil –Modified Glass Ionomer Cement Versus Nanosilver Or Nanogold-Modified Glass Ionomer Cements: An In-Vitro Study, Rania Ezzat Bayoumi Assistant Professor, Shaymaa Ibrahim Habib Assistant Professor

Future Dental Journal

Objectives: Evaluation of antibacterial activity of glass ionomer restorative material (GIC) after impregnation of copaiba oil, nanosilver (NanoAg) and nanogold (NanoAu) and their consequent effect on the compressive strength. Methodology: The different antibacterial solutions were added to Fugi IX GI liquid at various concentrations; 50 μL, 100 μL, 150 μL, 200 μL and 250 μL. Antibacterial activity against streptococcus mutans was evaluated by agar diffusion test (ADT) and direct contact test (DCT). Compressive strength was assessed according to ISO specifications. Bactericidal effect of the different investigated antibacterial agents on S. mutans biofilms was evaluated using Conofocal laser scanning microscope (CLSM). …

Biofilm Forming Ability Of Bacteria Isolated From Dental Caries: With Reference To Streptococcus Species, Sonali Kaustubh Ambulkar, Vidya Tale, Abhijit Jadhav, Komal Kulkarni

Future Dental Journal

Dental caries is formed by the group of microorganisms attached to a tooth surface embedded in a matrix of polymers. Biofilm plays an important role in the development of dental caries, plaque and other periodontal diseases. The present study is aimed to isolate, identify and characterize bacteria from dental caries. The ability of biofilm formation of these isolates was confirmed by Congo red agar method, Tube method and Microtitre plate method. High biofilm-forming bacteria were identified by 16S rRNA sequencing. Streptococcus mutans, Streptococcus anginosus, Enterococcus faecalis and Rothia dentocariosa are the predominant biofilm forming bacteria associated with dental caries.

Using Cold Plasma As A Surface Treatment With Peek Dental Implant: A Case Series”., Mohamed Dohiem, Hebatalla Mahmoud El Afandy

Future Dental Journal

Background: Polyetheretherketone (PEEK) is a material that can be used instead of normal titanium implants. PEEK is considered inert and biocompatible, however, it has been shown to possess low surface energy and that leads to decreased osteointegration with bone, Recent researches have focused on increasing the bioactivity of PEEK by modifying the surface by chemical and physical means such as plasma treated surfaces.

The Purpose of this article to evaluate peek dental implant with cold plasma surface treatment

Materials In this case series an immediately loaded peek dental implant, treated with plasma surface activation method, was used to replace anterior …

Expression Of Mir-720 Is Correlated With Dnmt3 In Oral Squamous Cell Carcinomas, Andrew Graves, Sukhdeep Sandhu, Karl Kingsley

Dental Medicine Faculty Research

Background: Many factors are involved with cellular differentiation and pluripotency, such as long non-coding and microRNAs (miRNA). miR-720 has been demonstrated to affect development, differentiation and pluripotency in dental pulp stem cells but has also been linked to many cancers (renal, prostate, skin, colorectal, breast, cervical and esophageal) through shared pathways including DNA methyltransferase family members (DNMT)3a and DNMT3b, which are highly upregulated in many oral cancers. However, little is known about the expression (or function, if expressed) of miR-720 in oral cancers. Based upon this lack of information, the primary objective of this project was to evaluate the expression …

Prevalence Of Hyperdontia, Hypodontia, And Concomitant Hypo-Hyperdontia, Nareh Eshgian, Tanya Al-Talib, Stanley Nelson, Neamat Hassan Abubakr

Dental Medicine Faculty Research

Background/purpose: Anomalies in human dentition are some of the most common occurrences of congenital abnormalities. Present study aimed to determine the prevalence of hypodontia, hyperdontia and concomitant hypo-hyperdontia (CHH) among patients attending the University of Nevada, Las Vegas (UNLV) School of Dental Medicine clinics. Materials and methods: Retrospective search was conducted on patients’ clinical notes in AxiUm. Search included using keywords such as “hypodontia”, “hyperdontia”, “supernumerary teeth” and “congenitally missing”. Panoramic radiographs were used to confirm the hyperdontia, hypodontia or CHH for patients attending the UNLV SDM clinics from 2010 to 2018. Collected data were analyzed using the chi-square test. …

Ada News - 09/21/2020, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Multilocular Radiolucency Of The Mandibular Ramus And Body, Galal Omami

Oral Health Practice Faculty Publications

No abstract provided.

Ada News - 09/07/2020, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Multicentric Synchronous Giant Cell Granulomas Of The Mandible, Galal Omami

Oral Health Practice Faculty Publications

No abstract provided.

Improving Dental Hygiene Students' Journal Writing, Susan Davide

Publications and Research

During the introductory semester of treating patients, students are in need of assistance and guidance throughout the assessment and treatment phases of patient care. As novice learners, there is little to no prior knowledge on writing a patient case study presentation. To assist and improve dental hygiene student writing of patient case journals, a scaffold assignment was created. Over the course of the semester students were required to submit five patient case studies in the form of a journal. Each journal had a writing focus with specific directions for each along with a detailed rubric; the final journal encompassing all …