Dentistry Commons^™

The Effect Of Acemannan In Implant Placement With Simultaneous Bone Graft In Esthetic Zone : A Randomized Controlled Trial, Nataporn Deesricharoenkiat

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: Acemannan, a linear polysaccharide produced by Aloe vera has been shown to have important biological functions promoting wound healing and tissue regeneration. Objective: The aim of this randomized clinical trial was to investigate the impact of acemannan in guided bone regeneration (GBR) with simultaneous implant. Materials and methods: Twenty patients were randomly allocated to test- (Deproteinized bovine bone with Acemannan particulate with mean size of 32.45µm) and control groups (Deproteinized bovine bone only). Twenty implants were placed with simultaneous GBR. CBCT radiographic measurements were conducted immediately and at 3- and 6-months post-surgery. Vertical and horizontal dimensions of the buccal …

Cephalometric Study Of Treated Orthodontic Patients With Acceptable Esthetic Profiles Compared To Adult Thai Normative Values, Visessan Pornsirianand

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objective: This study aimed to compare cephalometric variables between esthetically acceptable normal, concave, and convex profile groups as well as between each group and adult Thai normative values. Materials and Methods: Three-hundred and three profile silhouettes from post-treatment lateral cephalometric radiographs of 18–37 year-old orthodontic patients were scored by 5 Thai orthodontists and 15 orthodontic patients. The Likert 5-point scale was used to judge the attractiveness. Two-hundred and seven radiographs passing the minimum score of 3 were divided into acceptable normal, concave, and convex profile (AN, ACC, ACV) groups. Thirty-five skeletal, 17 dental, and 34 soft tissue cephalometric variables were …

J Mich Dent Assoc January 2020

The Journal of the Michigan Dental Association

Every month, The Journal of the Michigan Dental Association brings news, information, and features about Michigan dentistry to our state's oral health community and the MDA's 6,200+ members. No publication reaches more Michigan dentists!

In this issue, the reader will find the following original content:

• A cover story on "Preventing Pediatric Obesity: How the Dental Team Can Help”.
• “We Can Make a Difference in a Child’s Life”, a feature with a special message to MDA members from Suzanne Port, DDS, MS, president of the Michigan Academy of Pediatric Dentistry.
• A feature on “The Age-1 Visit: Time to Welcome Children into …

Global Interest For Health Professions Education: A Geographic And Temporal Analyses Through Web Search Differences From 2010-2019, Junhel Dalanon, Yoshizo Matsuka

Internet Journal of Allied Health Sciences and Practice

Purpose: The purpose of this study was to analyze the spatio-temporal differences in web search trends for dental degrees (DD), medical degrees (MD), and nursing degrees (ND) across 197 countries from 2010 to 2019. Method: A search string was used to initiate a search query using Google Trends. The parameters used were DD, MD, and ND as search terms; worldwide as Location; 2010 to 2019 as time range; health education & medical training as category; and web search as database. Data were downloaded and analyzed. Results: Via one-way ANOVA and post hoc Dunnett test, the searches for DD were found …

Mitochondrial Oxidative Phosphorylation Complex Regulates Nlrp3 Inflammasome Activation And Predicts Patient Survival In Nasopharyngeal Carcinoma, I. Che Chung, Lih Chyang Chen, Ngan Ming Tsang, Wen Yu Chuang, Tzu Chieh Liao, Sheng Ning Yuan, Chun Nan Ouyang, David M. Ojcius, Chih Ching Wu, Yu Sun Chang

All Dugoni School of Dentistry Faculty Articles

© 2020 Chung et al. We previously reported that tumor inflammasomes play a key role in tumor control and act as favorable prognostic markers in nasopharyngeal carcinoma (NPC). Activated inflammasomes frequently form distinguishable specks and govern the cellular secretion of IL-1β. However, we know little about the biological and biochemical differences between cells with and without apoptosis-associated speck-like protein containing a caspase-recruitment domain (ASC) speck formation. In this study, we used proteomic iTRAQ analysis to analyze the proteomes of NPC cells that differ in their ASC speck formation upon cisplatin treatment. We identified proteins that were differentially over-expressed in cells …

Immune Response Against Chlamydia Trachomatis Via Toll-Like Receptors Is Negatively Regulated By Sigirr, Mufadhal Al-Kuhlani, Graham Lambert, Sukumar Pal, Luis De La Maza, David M. Ojcius

All Dugoni School of Dentistry Faculty Articles

Copyright: © 2020 Al-Kuhlani et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Chlamydia trachomatis is the most common bacterial sexually-transmitted infection and the major cause of preventable blindness worldwide. The asymptomatic nature of many infections along with uncontrolled inflammation leads to irreversible damage in the upper genital tract and the tarsal conjunctivae, with the major complications of infertility and chronic pelvic pain, and blindness, respectively. Inflammation must, therefore, be tightly regulated to …

Possible Role Of Tryptophan And Melatonin In Covid-19, Musthafa Mohamed Essa, Hamdan Hamdan, Saravana Babu Chidambaram, Buthainah Al-Balushi, Gilles J. Guillemin, David M. Ojcius, M. Walid Qoronfleh

All Dugoni School of Dentistry Faculty Articles

No abstract provided.

Sleep Deprivation And Neurological Disorders, Muhammed Bishir, Abid Bhat, Musthafa Mohamed Essa, Okobi Ekpo, Amadi O. Ihunwo, Vishnu Priya Veeraraghavan, Surapaneni Krishna Mohan, Arehally M. Mahalakshmi, Bipul Ray, Sunanda Tuladhar, Sulie Chang, Saravana Babu Chidambaram, Meena Kishore Sakharkar, Gilles J. Guillemin, M. Walid Qoronfleh, David M. Ojcius

All Dugoni School of Dentistry Faculty Articles

Sleep plays an important role in maintaining neuronal circuitry, signalling and helps maintain overall health and wellbeing. Sleep deprivation (SD) disturbs the circadian physiology and exerts a negative impact on brain and behavioural functions. SD impairs the cellular clearance of misfolded neurotoxin proteins like α-synuclein, amyloid-β, and tau which are involved in major neurodegenerative diseases like Alzheimer's disease and Parkinson's disease. In addition, SD is also shown to affect the glymphatic system, a glial-dependent metabolic waste clearance pathway, causing accumulation of misfolded faulty proteins in synaptic compartments resulting in cognitive decline. Also, SD affects the immunological and redox system resulting …

Effects Of Electronic Cigarette Aerosol Exposure On Oral And Systemic Health, Cássio Luiz Coutinho Almeida-Da-Silva, Harmony Matshik Dakafay, Kenji O'Brien, Dallin Montierth, Nan Xiao, David M. Ojcius

All Dugoni School of Dentistry Faculty Articles

Conventional cigarette smoke harms nearly every organ of the body and is the leading cause of death in the United States and in the world. Decades of research have associated conventional cigarette smoke with several diseases and death. Heavily marketed, electronic nicotine delivery systems such as electronic cigarettes (e-cigarettes) are available in a variety of flavors and high nicotine concentrations. In 2019, a severe lung disease outbreak linked to e-cigarette use led to several deaths, which was called electronic-cigarette or vaping product use-associated lung injury (EVALI). Even though the trend of e-cigarette use among teens continues to increase, information on …

Protecting Public Health, Susan H. Davide, Christine Macarelli, Anty Lam

Publications and Research

In light of declining vaccination rates, oral health professionals need to be knowledgeable about current vaccine recommendations so they can best advise their patients and support public health.

Tobacco Cessation In A Dental School Setting, Kerri T. Simpson

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction

Tobacco use remains the single largest preventable cause of death in the United States. Currently, the prevalence of tobacco use is 20.7% in adults (≥18 years old) and 31.2% among high school students. According to various studies, over 60% of Americans want to quit tobacco, but it takes a person several attempts to quit before they are successful. There is limited data in the literature that discusses the effectiveness of tobacco cessation programs in US dental schools. Therefore, information on the effectiveness of a tobacco cessation program in a dental school setting could benefit this state and the problem …

Clear Aligner Therapy Vs. Traditional Brackets On Smile Arc, Sarah Elizabeth Larue

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background and Objectives: More so than ever, the public is becoming exceedingly aware of esthetics, and will evaluate their treatment outcome based upon the improvement to their smile and overall enhancement of their facial appearance. Smile arc is considered to be a key component of facial esthetics. Literature has demonstrated that orthodontic treatment mechanics utilizing traditional brackets and wires can cause flattening of the smile arc and that smiles with flatter arcs are judged to be less attractive. The aim of this study was to determine whether clear aligner therapy can help to preserve or improve the smile arc …

Wv Dental Hygienists' Knowledge And Educational Approach For Pregnant Women, Isabella Hope Mcdaniel

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Adverse pregnancy outcomes have become a concern for dental professionals caring for pregnant women with poor oral health. Pregnant women may not be aware of their increased risk of bacterial infections in their oral tissues and how it could relate to adverse pregnancy outcomes such as pre- term birth (PTB) and low birthweight babies (LBW). Dental healthcare professionals need to be well informed of risk related to poor oral health and have confidence to effectively educate pregnant women. PTB and LBW babies account for 1 million infant deaths annually. It is the responsibility of dental healthcare professionals to be …

Fracture Resistance Of Simulated External Cervical Resorption In Anterior Teeth Restored With And Without A Fiber Post., Michelle M. Romeo

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction: External cervical resorption (ECR) is a destructive type of external resorption that can be difficult to treat. ECR usually begins subgingival at the cementoenamel junction of teeth and continues apically and circumferentially. This substantial loss of tooth structure may make these teeth more prone to fracture and should be addressed when treatment planning teeth with ECR. The aim of this in vitro study was to evaluate the fracture resistance of treated and non-treated teeth with simulated ECR using two different treatment modalities.

Materials and Methods: Forty-eight extracted human permanent mandibular central incisors were selected. Teeth were randomly divided into …

The Pattern Of Odontogenic Referred Pain, James J. Poulos

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Referred odontogenic pain (RP) is a phenomenon that is seen regularly in dentistry and it is not extensively understood. It can make formulating a proper diagnosis difficult and its presence can lead to inappropriate treatment.

Methods: 250 patients experiencing odontogenic pain within the dental clinics of West Virginia University were surveyed. The survey inquired about the patient’s biographical information, medical history, characteristics of the pain, the presence and location of RP, and the psychosocial effects of the pain. Additionally, the endodontic diagnosis of the offending tooth was determined by a member of the endodontic department. The collected …

Comparison Of Skeletal And Dentoalveolar Changes Between Two Bone-Borne Maxillary Expanders, Mohamad Sarraj

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction: Bone-borne maxillary expander (BBME) are designed to provide additional anchorage to widen the maxillary arch for patients who exhibit maxillary transverse deficiency. One form of BBME is the hybrid BBME which uses mini-implants (bone-borne) and posterior teeth (tooth-borne) as anchorage for maxillary expansion. The other form of BBME is absolute BBME which only uses mini-implants as anchorage. It is not clear in the literature if there is a difference in skeletal and dental changes with these two types of expanders. The objective of this study was to compare the skeletal, dentoalveolar, and periodontal changes between the hybrid and the …

The Visual And Spectrophotometric Effect Of External Bleaching On Omnichroma Resin Composite And Natural Teeth, Michael Brian Evans

Graduate Theses, Dissertations, and Problem Reports (ETD)

Objective: To determine the visual and spectrophotometric effect external tooth bleaching has on natural tooth structure and OMNiCHROMA composite at various number of treatments. Variables were compared to determine if there is a detectable difference between the composite and the tooth before and after bleaching.

Methods: Preparation and restoration of 25 previously extracted teeth was completed. OMNiCHROMA composite was used. Each tooth was measured visually with a VITA shade guide and a colorimeter. Measurements were recorded before bleaching, after 5 and 10 treatments. Statistical analysis was completed and ΔE values between the composite and tooth were compared between the 3 …

Bond Of Resin Cements Through Three Ceramics At Varying Thickness, Po-Hsu Chen

All ETDs from UAB

The purpose of this study was to determine the bond strength of a light cured resin when cured through 3 different types of dental ceramics (traditional zirconia with 3 mol% yttria, translucent zirconia with 5 mol% yttria, and lithium disilicate) at 2 different thicknesses. A total of 135 specimens were prepared from traditional zirconia (IPS e.max ZirCAD LT, Ivoclar Vivadent, Liechtenstein), translucent zirconia (IPS e.max ZirCAD MT, Ivoclar Vivadent, Liechtenstein), and lithium disilicate (IPS e.max CAD LT, Ivoclar Vivadent, Liechtenstein) into a plate shape, but in different thicknesses (1mm and 1.5mm). Ceramic buttons were fabricated by pressed lithium disilicate (IPS …

Calibration Of Periodontal Diagnosis Among Participants Of Various Dental Education Levels, Shadi Alkhoury

All ETDs from UAB

ABSTRACT: The purpose of this project is to assess the level of calibration among dental students of two different education levels and postgraduate students of two different dental specialties during diagnosis and treatment planning of clinical cases with various levels of periodontal involvement, using the 2018 Classification of Periodontal and Peri-implant Diseases and Conditions. Fifty-seven second year dental students (D2), 45 fourth year dental students (D4), 17 orthodontic postgraduate students (OS) and 12 postgraduate periodontology (PS) students were presented with an anonymous survey of 10 different cases, each with 5 choices of diagnosis and 7 therapeutic approaches. Consensus diagnosis was …

Functional Significance Of Senescence And Autophagy In Cancer-Associated Fibroblasts From Oral Squamous Cell Carcinoma, May Leng Tan

Student Works (2020-2029)

Oral squamous cell carcinoma (OSCC) is a malignancy that arises from the epithelial cells within the oral cavity. It accounts for approximately 355,000 new cases worldwide and is exceptionally prevalent in particular geographical areas such as Papua New Guinea, the Indian subcontinent and South-East Asian countries. Despite advances in surgical management and therapeutic approaches, the five-year survival rate of OSCC patients has not improved significantly over the past few decades. The mortality associated with OSCC is particularly high often due to late presentation, locoregional recurrence, distant metastases and the development of second primary tumours. A comprehensive understanding of the molecular …

Impacts Of Self-Perceived Malocclusion On The Oral Health-Related Quality Of Life Of Young Adults In Malaysia, Mohd Tajudin Zawani

Student Works (2020-2029)

Objectives: To assess the prevalence, severity and extent of impacts of self-perceived malocclusion on the oral health-related quality of life (OHRQoL) related to dental aesthetics among young Malaysian adults, to compare between those with and without self-perceived malocclusion and to investigate the influence of demographics on the outcome. Methods: Multi-stage random sampling method was used to recruit 589 subjects from tertiary institutions in Malaysia. Study instruments comprised the Aesthetic Component of the Index of Orthodontic Treatment Need (AC-IOTN) and Malaysian version of the Psychosocial Impact of Dental Aesthetics (PIDA) to measure selfperceived malocclusion and its impacts. Analyses included multifactorial ANOVA …

Anticancer Activity Of Ficus Deltoidea And Tualang Honey On Oral Cancer Cells: An In Vivo Study, Alkoshab May Ameen Saeed

Student Works (2020-2029)

The use of natural products have been gaining interest, notably in the area of cancer therapy and in this study, natural products rich in antioxidants such as Tualang Honey (Malaysian wild local honey) and Ficus deltoidea (Malaysian local herbal plant), were selected to assess their chemo-preventive and chemotherapeutic activities on oral cancer. The aim of this study is to evaluate the chemo-preventive and chemotherapeutic activities of Ficus deltoidea (FD) and Tualang Honey (TH) in an animal model induced for oral cancer using 4-Nitroquinoline1-oxide (4NQO). A total of 70 male Sprague-Dawley (SD) rats were distributed into ten groups (n=7 per group); …

Expression Of Ki-67, Fscni And Tnfrsf 12a In Histologically Non-Involved Mucosal Surgical Margins As Predictive Markers For Local Relapse In Oral Squamous Cell Carcinoma, Zainul Abidin Nur Fauziani

Student Works (2020-2029)

Introduction: The presence tumour-related genetic alterations in histologically noninvolved mucosal surgical margins was linked to development of local relapse in OSCC. Aims: The present study aimed to determine the association between expression of Ki67, FSCN1 and TNFRSF12A in histologically non-involved mucosal surgical margins of OSCC patients and local relapse. Materials and methods: The study involved a total of 34 OSCC cases including 15 cases of patients who had relapse within the 5 years followup period and 19 cases of patients who did not had relapse. Two-stage sampling was carried out to select the margins’ site, followed by the representative sections …

Clinicopathological Study Of Oral Lichen Planus And Oral Linchenoid Reaction, Gubod Eb Robson

Student Works (2020-2029)

Introduction: Oral lichen planus is a chronic inflammatory disease that affects the mucosa of the oral cavity. Oral lichenoid reactions/ lesions share many clinical and histopathological features with oral lichen planus, and represent a response to extrinsic or causative factors (drugs, allergens). Aim: The purpose of this study was to evaluate the clinical and histopathological features of oral lichen planus and oral lichenoid reactions/ lesions. Objectives: The objectives of this study were to assess the clinical and histopathological features of patients diagnosed with oral lichen planus and oral lichenoid reaction/ lesions. This study also sought to investigate the association between …

A Three Dimensional Age Estimation Using Cone Beam Ct In Malaysian Population, Asif Muhammad Khan

Student Works (2020-2029)

Forensic odontology plays a vital role in the age estimation and identification process during criminal investigations. Forensic science in the past have mainly employed two-dimensional (2D) radiographic assessment of developmental and physiological age related dental parameters for age estimation. However, 2D radiograph doesn’t represent the three-dimensional (3D) anatomical structures. Rapidly evolving CBCT imaging modality can be effectively employed in forensic sciences to overcome the limitations of 2D imaging. The current study aimed to develop a novel method of dental age estimation using 3D surface area analyses of root apices of the developing permanent maxillary canines and mandibular third molars among …

Single Nucleotide Polymorphism Of Prostaglandin-Endoperoxide Synthase (Ptgs2) And Defensin Beta 1 (Defb1) Genes In Malay Chronic Periodontitis Subjects, Jagender Singh Jasmin Kaur

Student Works (2020-2029)

The association of prostaglandin-endoperoxide synthase 2 (PTGS2) and defensin beta 1 (DEFB1) single nucleotide polymorphisms (SNP) with chronic periodontitis (CP) have been widely studied amongst different ethnic groups such as the Chinese and European population. Thus far, no study has been done on the Malay ethnic group. Hence, this study assessed the allele and genotype frequencies of PTGS2 and DEFB1 variants in subjects with CP and periodontally healthy individuals in Malaysian Malays. Samples of 78 Malay CP subjects and 62 periodontally healthy controls were obtained from Malaysian Periodontal Database and Biobanking system (MPDBS) for this study. DNA samples were genotyped …

Preschool Children's Toothbrushing Behaviour And Association With Their Oral Health, Muhammad Khan Iqra

Student Works (2020-2029)

Toothbrushing is an important yet neglected behaviour that has affected oral health of preschool children (4-6 years). Factors like dietary habit, socioeconomic status and oral conditions also affect oral health of preschool children. Despite intervention efforts, recent investigations reported high prevalence of early childhood caries (ECC) and oral diseases among this age group across different populations. Therefore, it is imperative to understand the relationship between toothbrushing behaviour and oral health status of preschool children to prevent oral diseases, hence improve their oral health. The aim of the current study was to evaluate toothbrushing behaviour of preschool children, assess their oral …

Identification Of Potential Biomarkers Of Oral Squamous Cell Carcinoma Using Integrated Proteomics And Glycoproteomics And Glycoproteomics Analyses, Yin Ling Wong

Student Works (2020-2029)

Oral cancer is one of the major health concerns worldwide. The 5-year survival rate of oral squamous cell carcinoma (OSCC) has remained at approximately 50% over the past decades. Most OSCCs are diagnosed at an advanced stage due to the delay in diagnosis, suggesting an imperative need in identifying reliable biomarkers to improve the diagnosis, prognosis, and treatment of OSCC. This study aimed to identify potential biomarkers that are involved in the development and progression of OSCC using integrated proteomics and glycoproteomics analyses. Proteomics analysis was performed on serum samples of 10 patients with oral potentially malignant disorder (OPMD), 40 …

Patient Concerns Inventory Head And Neck As An Individualised Approach To Assess Post-Treatment Outcomes Among Oral Cancer Patients In Malaysia, Aminnudin Ainon Natrah

Student Works (2020-2029)

Background: Oral cancer and its treatment undisputedly impacts patients‘ quality of life, posing a challenge to clinicians in managing them optimally. Identifying patients‘ concerns is central to holistic patient care; as such time constraints faced by clinicians during consultation sessions may pose a barrier in identifying such concerns effectively. The use of PCI-H&N during post-treatment oral cancer consultation sessions has previously shown to be beneficial, simultaneously promoting effective patient- clinician communication during consultations. Objectives: This study aimed to determine the feasibility of the PCI-H&N in assessing post- treatment oral cancer patients concerns and its relationship with patients‘ HRQoL, psychological distress …

Tubular Adenoma Of Breast, Diksha Dadlani

Digital Journal of Clinical Medicine

No abstract provided.