Dentistry Commons^™

Mentors And Role Models: Two Approaches For Inspiration, Gary L. Stafford

School of Dentistry Faculty Research and Publications

No abstract provided.

Microfluidic Manipulation Of Core/Shell Nanoparticles For Oral Delivery Of Chemotherapeutics: A New Treatment Approach For Colorectal Cancer, Mohammad Mahdi Hasani-Sadrabadi, Shahrouz Taranejoo, Erfan Dashtimoghadam, Ghasem Bahlakeh, Fatemeh Sadat Majedi, Jules John Vandesarl, Mohsen Janmaleki, Fatemeh Sharifi, Arnaud Bertsch, Kerry Hourigan, Lobat Tayebi, Phillippe Renaud, Karl I. Jacob

School of Dentistry Faculty Research and Publications

A microfluidics approach to synthesize core–shell nanocarriers with high pH tunability is described. The sacrificial shell protects the core layer with the drugs and prevents their release in the severe pH conditions of the gastrointestinal tract, while allowing for drug release in the proximity of a tumor. The proposed nanoparticulate drug-delivery system is designed for the oral administration of cancer therapeutics.

Three-Dimensional Bioprinting Materials With Potential Application In Preprosthetic Surgery, Mina D. Fahmy, Hossein E. Jazayeri, Mehdi Razavi, Radi Masri, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Current methods in handling maxillofacial defects are not robust and are highly dependent on the surgeon’s skills and the inherent potential in the patients’ bodies for regenerating lost tissues. Employing custom-designed 3D printed scaffolds that securely and effectively reconstruct the defects by using tissue engineering and regenerative medicine techniques can revolutionize preprosthetic surgeries. Various polymers, ceramics, natural and synthetic bioplastics, proteins, biomolecules, living cells, and growth factors as well as their hybrid structures can be used in 3D printing of scaffolds, which are still under development by scientists. These scaffolds not only are beneficial due to their patient-specific design, but …

Removable Partial Dentures Vs Overdentures In Children With Ectodermal Dysplasia: Two Case Reports, Georgios Maroulakos, Ioli I. Artopoulou, Matina V. Angelopoulou, Dimitris Emmanouil

School of Dentistry Faculty Research and Publications

Ectodermal dysplasia (ED) represents a disorder group characterised by abnormal development of the ectodermal derivatives. Removable partial dentures (RPD), complete dentures (CD) or overdentures (OD) are most often the treatment of choice for young affected patients. Prosthetic intervention is of utmost importance in the management of ED patients, as it resolves problems associated with functional, aesthetic, and psychological issues, and improves a patient’s quality of life. However, few studies present the principles and guidelines that can assist in the decision-making process of the most appropriate removable prosthesis. The purpose of this study was to suggest a simple treatment decision-making algorithm …

A Simplified Technique For Implant-Abutment Level Impression After Soft Tissue Adaptation Around Provisional Restoration, Ahmad Kutkut, Osama Abu-Hammad, Robert Q. Frazer

Oral Health Practice Faculty Publications

Impression techniques for implant restorations can be implant level or abutment level impressions with open tray or closed tray techniques. Conventional implant-abutment level impression techniques are predictable for maximizing esthetic outcomes. Restoration of the implant traditionally requires the use of the metal or plastic impression copings, analogs, and laboratory components. Simplifying the dental implant restoration by reducing armamentarium through incorporating conventional techniques used daily for crowns and bridges will allow more general dentists to restore implants in their practices. The demonstrated technique is useful when modifications to implant abutments are required to correct the angulation of malpositioned implants. This technique …

Ada News - 05/16/2016, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Color Stability, Physical Properties And Antifungal Effects Of Zro2 And Tio2 Nanoparticle Additions To Pigmented Polydimethylsiloxanes, Mazen Alkahtany

Theses & Dissertations

Introduction: Color changes, physical degradation and fungal infections are potential challenges to the longevity of polydimethylsiloxane (PDMS) elastomers. The purpose of this study was to evaluate potential improvements in color change, physical properties and anti fungal properties of PDMS loaded with TiO2 and ZrO2 nanoparticles.

Methods: 1% weight of 40 nm or 200 nm diameter TiO2 or ZrO2 nanoparticles were mixed into PDMS with 2% functional intrinsic yellow pigment and polymerized. Control materials contained 13% weight 200 nm silica. Samples were exposed to either 3000 hours of UVB radiation (200 μW/cm2) or darkness. Color parameters L*a*b* and ΔE*, ultimate tensile …

Ada News - 05/02/2016, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Chhs May 2016 Icymi, Dr. John Bonaguro, Dean, Vashon S. Wells, Editor, Wku College Of Health & Human Services

College of Health & Human Services Publications

No abstract provided.

The Effect Of Ah Plus And Zinc Oxide Eugenol-Based Root Canal Sealers On Preventing Residual Bacteria In Dentinal Tubules From Accessing The Root Canal, Napapas Nidhidvanich, Panida Thanyasrisung, Pavena Chivatxaranukul

Chulalongkorn University Dental Journal

Background/objectives To investigate the ability of two root canal sealers in preventing residual bacteria in dentinal tubules from accessing the main root canal space. Materials and methods Thirty-five sterilized root samples were randomly assigned to 5 groups: Gutta percha+AH Plus sealer (AH Plus, n=10), Gutta percha+Zinc oxide eugenol sealer (ZOE, n=10), Gutta percha without sealer (GP, n=5), Flowable resin composite coating (composite, n=5), and noninfected samples+GP (aseptic control, n=5). All samples, except the aseptic control, were incubated with Enterococcus faecalis for 4 weeks. All canals were chemo-mechanically prepared and obturated according to the assigned groups. After 1 week, the filling …

Screw Retightening Increases The Implantabutment Connection Screw Loosening Resistance Of Two Implant Systems, Sudarat Nubdee, Ticha Kanchanapoomi, Wacharasak Tumrasvin, Trakol Mekayarajjananonth

Chulalongkorn University Dental Journal

Background/Objective To evaluate the effect of three screw-tightening methods on the screw loosening resistance of two dental implant systems. Materials and methods Fifteen Simple Line II dental implants and 15 CU dental implant abutments were screw tightened to their implant fixtures to the manufacturerûs recommended torque using three tightening methods (method 1: tightening the screw one time, method 2: tightening the screw and retightening the screw after 10 min, method 3: tightening the screw, loosening the screw, retightening the screw, and then retightening the screw after 10 min). After a 106-cycle fatigue test, the reverse torque values were measured. The …

Depth Of Cure, Flexural Strength, Microhardness, And Cytotoxicity Of Light Activated Pit And Fissure Resin-Based Sealant Experimental Prototypes, Pasutha Thunyakitpisal, Sirithan Jiemsirilers, Dujreutai Pongkao Kashima, Onusa Saravari, Nonglax Thunyakitpisal, Thitima Rupunt

Chulalongkorn University Dental Journal

Objective To evaluate the light-activated pit and fissure resin-based sealant prototypes (LAS-clear and LAS-opaque) for depth of cure, flexural strength, microhardness, and cytotoxicity compared with commercial light-activated pit and fissure resin-based sealants. Material and methods LAS-clear, LAS-opaque, Delton-clear (DC), Helioseal clear (HC), Helioseal opaque (HO), and Clinpro (CL) were investigated for depth of cure per ISO 6874:2005. Their flexural strength and microhardness were also evaluated. Cytotoxicity was determined using an MTT based colorimetric assay. Statistical analysis was performed using the SPSS program. Results All materials met ISO 6874:2005 requirements. The mean depth of cure of DC, HC, and LAS-clear were …

Pneumatization Of The Sphenoid Sinus On A Panoramic Radiograph, Pipop Sutthiprapaporn, Pornpop Rattana-Arpha

Chulalongkorn University Dental Journal

The paranasal sinuses are composed of a set of structures of the maxillofacial region and its proximity to the oral cavity. The sphenoid sinus is located within the body of the sphenoid bone. However, an excessive pneumatization of this structure may cause difficulties in radiographic diagnosis, particularly with panoramic radiographs. This article describes a case of pneumatization of the sphenoid sinus in the pterygoid process and greater wing of the sphenoid bone, presented on a panoramic radiograph. Cone beam computed tomography in axial and coronal sections was performed to confirm the pneumatization of these structures.

New Dentist News (May 2016), Ada Committee On The New Dentist

New Dentist News

New Dentist News offers timely information on scientific, social, educational, political and economic developments affecting new dentists. This collection is historical and items may not reflect current standards. For up-to-date information contact the ADA. The New Dentist News was alternately titled ADA Lifeline, 1997-June 2001.

Filifactor Alocis, A Newly Appreciated Oral Pathogen, Fails To Induce The Respiratory Burst Response Of Human Neutrophils., Jacob S. Edmisson

College of Arts & Sciences Senior Theses

Almost 50% of adult Americans suffer from periodontitis which is a bacterially induced inflammation of the tissue that surround and support the tooth. The accumulation of neutrophils, a critical cell component of the innate immune system, in the gingival crevice contributes to tissue damage. Filifactor alocis is a newly appreciated pathogen present in oral biofilms at periodontal disease sites. Studying the interactions between neutrophils and F. alocis will provide valuable information for delineating the role of this bacterium in periodontal disease and enhance our understanding of bacterial strategies to evade leukocytes’ antimicrobial mechanisms. The hypothesis that F. alocis modulates human …

Long Term Facial Alveolar Bone Changes Associated With Endosseous Implants In The Anterior Maxilla., Deepika Joshi

Electronic Theses and Dissertations

Aim: To quantify the radiographic presence and thickness of facial alveolar bone (FAB_r) adjacent to implants placed in the anterior maxillary region. Lack of FAB_r may suggest that graft procedures are desirable prior to implant placement. Material and Methods: With IRB approval, a retrospective analysis of cone beam computed tomographic cross-sectional images of sites with at least one implant in the anterior maxillary region was performed. Details regarding type of implant and location were recorded. FAB_r perpendicular to the long axis each implant was measured at seven levels by two observers independently and means and standard …

Influence Of In-Office Oral Hygiene Instructions On The Parental Assessment Of Their Child's Oral Health., Sireesha Kodali

Electronic Theses and Dissertations

Purpose: To identify the relation between oral health education and parental assessment of their child’s dental condition. Methods: Our study population included 33,342 children, from Smile KY! annual screenings from 2002 to 20014. Data collection was through questionnaire forms. Our primary risk factor was “dental health instructions received” (yes/no) and our outcome of interest was “parental assessment of your child’s dental health” (good/fair/poor). We had 13 years of data from 2002 to 2014 and used ‘SAS’ statistical software for data manipulation and recoding. Descriptive statistics, chi-square test of independence, trend analysis and multiple logistic regression modeling were performed on ‘SPSS’ …

Contribution Of Probiotics Streptococcus Salivarius Strains K12 And M18 To Oral Health In Humans: A Review, Turner A. Stowik

Honors Scholar Theses

The overgrowth and disequilibrium of pathogenic microorganism species both native and non-native to the oral cavity can manifest into a variety of different oral diseases, pathologies, and afflictions in humans, including dental caries, gingivitis, pharyngitis, halitosis, and oral candidiasis. Two bacterial strains with clinically-significant probiotic applications in curtailing the pathogenic bacterial growth involved in these conditions are Streptococcus salivarius strain K12 and Streptococcus salivarius strain M18. To summarize the most up-to-date in vitro, in vivo, and clinical research findings, administration of these S. salivarius strains typically in the form of probiotic lozenges results in colonization, reduction in inflammatory measures, …

Advances In Endodontics: Potential Applications In Clinical Practice., Anil Kishen, Ove A. Peters, Matthias Zehnder, Anibal R. Diogenes, Madhu K. Nair

All Dugoni School of Dentistry Faculty Articles

Contemporary endodontics has seen an unprecedented advance in technology and materials. This article aimed to review some of the challenges and advances in the following sections: (1) endodontic imaging, (2) root canal preparation, (3) root canal disinfection, (4) root canal filling, and (4) regenerative endodontic procedures (REPs). Jointly, these advances are aimed at improving the state of the art and science of root canal treatment.

Neurotrophic Factors: Promising Candidates In Tissue Regeneration, Nan (Tori) Xiao

All Dugoni School of Dentistry Faculty Articles

No abstract provided.

Objective Evaluation Of Clinical Shade-Matching Outcomes., Erin Ballard

Electronic Theses and Dissertations

The purpose of this study was to objectively evaluate shade-matching outcomes within an academic institution. Using the Spectrophotometer, E was calculated between the reference shade: restoration shade () and restoration shade: prescription shade (). The t-test was used to determine if E maintained clinical acceptance at E: 3.7. Satisfaction with shade-match and need for objective measurement were surveyed using a Five Point Likert Scale. Correlational relationships were assessed via Pearson Correlation. Mean E values were above the acceptance value (pppp

Modification Of T9ss Cargo Proteins Of Porphyromonas Gingivalis For Their Secretion In Soluble Form And Purification By Affinity Chromatography., Apoorv Goel

Electronic Theses and Dissertations

Background: Porphyromonas gingivalis, a keystone-pathogen associated with periodontitis, utilizes the Type IX Secretion System (T9SS) to secrete proteins bearing the conserved C-terminal domain (CTD), many of which are essential virulence factors. These include, besides gingipains and PPAD, 29 other proteins. During or after the outer membrane translocation the CTD is cleaved off and a glycan moiety is covalently attached anchoring the secreted proteins at the bacterial cell surface. Objective: Most of the CTD bearing proteins have only hypothetical functions assigned. It is plausible that these CTD bearing proteins may also play a crucial role in P. gingivalis pathogenesis. Therefore, …

Tobacco-Gene Activity Profile In Porphyromonas Gingivalis, Filifactor Alocis And Treponema Denticola., Neelima Chowdary Cherukumalli

Electronic Theses and Dissertations

Smoking is an established risk factor for periodontitis. Prior studies have shown that cigarette smoke extract (CSE) can induce profound phenotypic changes in Porphyromonas gingivalis and alters the virulence of this important periodontal pathogen. We hypothesized that CSE might also alter gene expression in established periodontal pathogens, Porphyromonas gingivalis and Treponema denticola, as well as in the emerging pathogen, Filifactor alocis. Oral bacteria were grown in CSE-conditioned medium (1000 ng/ml nicotine equivalents) or in unconditioned control medium. Total RNA was extracted and CSE-regulated genes were identified by comparison of the mRNA profiles of CSE with control cultures using RNA-Seq …

Porphyromonas Gingivalis Gingipains Induce A Pro-Inflammatory Extracellular Microenvironment : The Role Of Par-2 And Fibronectin., Jeffrey S. Marschall

Electronic Theses and Dissertations

Periodontitis is a chronic inflammatory disease that is characterized by severe tissue destruction of the gingiva and other tooth supporting structures; if left untreated, tooth loss and disintegration of the alveolar bone occurs. This chronic inflammatory state has been linked to other systemic diseases such as cardiovascular disease, diabetes, rheumatoid arthritis, and Alzheimer’s disease. Porphyromonas gingivalis is the major pathogenic microbe in periodontitis. The main virulence factors of P. gingivalis are the Arg-aa and Lys-aa gingipains, which are proteolytic enzymes implicated in a plethora of activities that allow P. gingivalis to subvert the human immune system in the oral cavity …

Expanding Interprofessional Learning Opportunities: How Dental Hygiene Administrators And Faculty Perceive Interprofessional Education, Cristina Casa

All Theses And Dissertations

The health care system has undergone transformation, implementing an interprofessional approach to patient care. Professionals have formed collaborative practice groups that effectively respond to the intricacies of today’s medical industry. Dental hygienists are underemployed in these teams. This has a direct effect on dental hygiene academia because education is the basis for practice. Interprofessional education (IPE) has been proposed as the strategy to adequately address this issue; however, many dental hygiene programs do not focus on shared teaching and learning.

This mixed methodology study documented the perspectives of dental hygiene administrators and faculty at higher education institutions in the Northeast …

Acrylic Resin Guide For Locating The Abutment Screw Access Channel Of Cement-Retained Implant Prostheses, Ayman Ahmed, Georgios Maroulakos, Jorge Garaicoa

School of Dentistry Faculty Research and Publications

Abutment screw loosening represents a common and challenging technical complication of cement-retained implant prostheses. This article describes the fabrication of a simple and accurate poly(methyl methacrylate) guide for identifying the location and angulation of the abutment screw access channel of a cement-retained implant prosthesis with a loosened abutment screw.

Outcomes Of Primary Endodontic Therapy Provided By Endodontic Specialists Compared With Other Providers, Jacob Burry, Sheila E. Stover, Fredrick Eichmiller, Pradeep Bhagavatula

School of Dentistry Faculty Research and Publications

Introduction

The objective of this study was to compare the outcomes of initial nonsurgical root canal therapy for different tooth types provided by both endodontists and other providers.

Methods

By using an insurance company database, 487,476 initial nonsurgical root canal therapy procedures were followed from the time of treatment to the presence of an untoward event indicated by Current Dental Terminology codes for retreatment, apical surgery, or extraction. Population demographics were computed for provider type and tooth location. Kaplan-Meier survival estimates were calculated for 1, 5, and 10 years. Hazard ratios for provider type and tooth location were calculated by …

Is Cell Viability Always Directly Related To Corrosion Resistance Of Stainless Steels?, E. Salahinejad, M. Ghaffari, Daryoosh Vashaee, Lobat Tayebi

School of Dentistry Faculty Research and Publications

It has been frequently reported that cell viability on stainless steels is improved by increasing their corrosion resistance. The question that arises is whether human cell viability is always directly related to corrosion resistance in these biostable alloys. In this work, the microstructure and in vitro corrosion behavior of a new class of medical-grade stainless steels were correlated with adult human mesenchymal stem cell viability. The samples were produced by a powder metallurgy route, consisting of mechanical alloying and liquid-phase sintering with a sintering aid of a eutectic Mn–Si alloy at 1050 °C for 30 and 60 min, leading to …

The Effect Of Attachment Placement And Location On Rotational Control Of Conical Teeth Using Clear Aligner Therapy, Pouya Momtaz

UNLV Theses, Dissertations, Professional Papers, and Capstones

Objective: To determine the optimal method to correct rotations of conical teeth using

thermoplastic appliances with and without attachments.

Introduction: Despite the increasing popularity of clear aligner therapy there are still questions as to its effectiveness, efficiency, case selection and limitations. It has been reported that the full prescription for clear aligners is not expressed, and that the mean accuracy of any type of tooth movement using clear aligners is only 41% (Drake, 2012). One of the major limitations of clear aligner therapy is correction of rotated conical teeth, especially canines and premolars (Kravitz, 2008). According to Simon, et al. …

Bachelor Of Liberal Studies Degree Option For Pre-Dental Undergraduates At Bowling Green State University, David Westmeyer

Honors Projects

Admission to professional school programs has become more competitive than ever. There are a lot of applicants with competitive GPAs and test scores. These “numbers” are no longer adequate for professional school matriculation. Admissions teams are now also looking for well-rounded students who have shown a commitment to service, leadership positions, commitment to their field of interest, and more. Students who are aware of these expectations become extremely busy attempting to fulfill all of these requirements.

One of the most difficult aspects of my dental school journey was to select an appropriate major. If I were able to redo my …