Dentistry Commons^™

Neural Crest Contributions To Dental Pulp Stem/Progenitor Cells And Craniofacial Structures: Alveolar Processes, Tongue And Temporomandibular Joint, Vinay Jain

Theses and Dissertations (ETD)

Background: The cranial neural crest, a transient embryonic structure in vertebrates, is crucial to craniofacial and dental development. Populations of multipotent stem cells have been identified in various dental tissues including dental pulp. Hence, identification of multipotent cells of neural crest lineage within dental pulp and delineation of neural crest contributions to various craniofacial tissues may be a step towards utilizing the potential of neural crest progenitor cells for therapeutic applications.

Objective: The overall purpose of the study was to identify a population of dental pulp stem/progenitor cells of neural crest lineage and demonstrate their neural differential potential and to …

Longitudinal Cephalometric Changes Of Orthodontic Patients Evaluated Long-Term, Lisa Ku

Theses and Dissertations (ETD)

Posttreatment changes are further complicated by the slow continued growth that occurs after treatment into adulthood. The purpose of this study was to examine long term posttreatment changes. The lateral cephalograms of 51 Caucasian females treated in the standard Edgewise practice of one private practitioner in Cookeville, TN were examined to investigate changes in the cranial base, nasomaxillary complex, mandible, interach relationships, dental relationships, and the soft tissue integumental profile that occured an average of 23 years posttreatment. Two tailed t-tests (α = 0.05) were run to see whether the posttreatment changes was statistically significantly different from zero. Craniofacial growth …

Cephalometric Evaluation Of Mara Therapy In The Treatment Of Class Ii Malocclusions, Tiffany Rachelle Mcclaran

Theses and Dissertations (ETD)

The effectiveness of functional appliances is a debatable topic in the orthodontic literature, primarily because the benefits have not been consistently reproduced among clinical studies. The present study was a retrospective cephalometric analysis of patients with Class II, division 1 malocclusions at the start of treatment. There were 51 children treated by a single clinician with a MARA in combination with Edgewise appliances. The comparison group consisted of subjects treated with fixed Edgewise appliances only from the University of Tennessee, Department of Orthodontics. Subjects in the two treatment groups were matched on a one-to-one basis for sex and for five …

The Effect Of Recombinant Human Bone Morphogenetic Protein-2 On The Osseointegration Of Temporary Anchorage Devices, Eden E. Cruz

Master's Theses

Titanium has been widely used for dental implants, and in particular, roughened titanium surfaces have provided a means for increasing bone apposition and strengthening the implant-to-bone interface. Finding a way to further increase osseointegration is important because there is a significant clinical benefit to patients if a stable anchor can be established instead of anchoring orthodontic hardware to the molars. In this study, the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) on the ability of temporary anchorage devices (TADs) to osseointegrate was investigated. The temporary anchorage devices (TADs) used in this study were manufactured from commercially pure titanium and …

Osseointegration Of Temporary Anchorage Devices Using Recombinant Human Bone Morphogenetic Protein-2, Erin E. Cruz

Master's Theses

Over the past 5 years, the use of titanium implants as temporary anchorage devices (TADs) has become an important tool in clinical orthodontic practices. The use of TADs have provided orthodontists a way of moving teeth against fixed objects rather than against the surrounding teeth, which tend to counteract desired motion. At present, viable attachment of TADs involves direct insertion through gingival tissue and piercing of the bone. Surface modifications such as sandblasted and acid-etched treatment or bone morphogenetic protein surface treatment, however, can be applied to the TADs to promote enhanced osseointegration, thereby allowing the TADs to serve as …

Tooth Loss, Apolipoprotein E, And Decline In Delayed Word Recall, P. S. Stein, R. J. Kryscio, M. Desrosiers, Sara J. Donegan, M. B. Gibbs

School of Dentistry Faculty Research and Publications

Our previous research suggests an association between a low number of teeth and increased risk of dementia. The aim of the present study was to determine if a low number of teeth is specifically related to memory decline as evidenced by low Delayed Word Recall scores. In addition, we examined the combined effect of a low number of teeth and the apolipoprotein E ϵ4 allele on Delayed Word Recall scores. We hypothesized that the scores of those who had the allele and a low number of teeth (0-9) would decline more rapidly over time than those participants with a greater …

Quantifying Fluid Shear Stress In A Rocking Culture Dish, Xiaozhou Zhou, Dawei Liu, Lidan You, Liyun Wang

School of Dentistry Faculty Research and Publications

Fluid shear stress (FSS) is an important stimulus for cell functions. Compared with the well established parallel-plate and cone-and-plate systems, a rocking “see-saw” system offers some advantages such as easy operation, low cost, and high throughput. However, the FSS spatiotemporal pattern in the system has not been quantified. In the present study, we developed a lubrication-based model to analyze the FSS distributions in a rocking rectangular culture dish. We identified an important parameter (the critical flip angle) that dictates the overall FSS behaviors and suggested the right conditions to achieving temporally oscillating and spatially relatively uniform FSS. If the maximal …

A Survey Of The Usage Of Topical Anesthesia Among Dentist, Lawrence Shults

Theses and Dissertations

Purpose: The purposes of this study were four-fold: 1) to determine the types and effectiveness of various topical anesthetics being used among dentists currently treating children, 2) to determine the types of procedures for which topical anesthetics are being used among children, 3) to understand the awareness and use of a relatively newer compounded topical gel Oraqix (Dentsply Caulk) among children, 4) to understand the adverse reactions to topical anesthesia that are seen among children. Methods: A cross sectional survey was designed, regarding the type, procedural use, effectiveness, and adverse reactions noted among children to various topical anesthetics. The survey …

Oral Health Status Of Children In The Child Health Investment Partnership (Chip) Program, Latrice Foster

Theses and Dissertations

Purpose: The purpose of this study is to describe children’s dental disease status and functional health literacy of families enrolled in the Child Health Investment Partnership program in Roanoke Valley. Methods: This was a prospective cohort study of children (n=166) enrolled in the Child Health Investment Partnership of Roanoke Valley, Virginia (CHIP). The parents of the 166 children completed the Life Skills Progression (LSP) survey at enrollment between September 2004 and September 2008 to assess their functional health literacy levels. Their LSP scores were used to determine their subsequent health care literacy (HCL), personal health literacy (PHL), and dental-child utilization …

Agenda (Pdf), School Of Dentistry

LSU School of Dentistry Research Day

No abstract provided.

Impact Belize 2010 Executive Report, Ritchie D. Taylor, Jordan Norris, Molly Calico, Bernie Strenecky, Daniel Carter, Dawn Garrett Wright, Eve Main, Bonny Petty, Molly Kerby, Jill Norris

Impact Belize

No abstract provided.

Genetic Variations Of Cyp2b6 Enzyme And The Response To Meperidine In Oral Sedation, Heath Whitfield

Theses and Dissertations

Purpose: The purpose of this study was to determine the relationship of the CYP2B6 genotype to the clinical response to meperidine in pediatric dental patients. Methods: Forty-nine patients, ASA I/ II, 41–101 months old, received an oral sedative regimen containing meperidine for dental treatment. The North Carolina Behavior Rating Scale (NCBRS) and Overall Effectiveness of Sedation Scale (OESS) were used to assess their behavior and sedation outcome. Saliva DNA samples were genotyped by PCR-RFLP. Results: We found the following genotype distributions: homozygous wild-type 1*1 (n = 19, 39%), heterozygous 1*6 (n = 25, 51%), and homozygous variant 6*6 (n = …

The Effects Of Motivational Interviewing In Pregnancy On Knowledge And Retention Of Infant Oral Health Information, Andrew Zima

Theses and Dissertations

THE EFFECTS OF MOTIVATIONAL INTERVIEWING IN PREGNANCY ON KNOWLEDGE AND RETENTION OF INFANT ORAL HEALTH INFORMATION By Andrew D. Zima, Jr., B.S., M.S., D.D.S. A thesis submitted in partial fulfillment of the requirements for the degree of Masters of Science in Dentistry at Virginia Commonwealth University. Virginia Commonwealth University, 2010 Major Director: Tegwyn H. Brickhouse, D.D.S., Ph.D Associate Professor, Department of Pediatric Dentistry Purpose: The purpose was to examine the effect of motivational counseling in pregnancy with readiness and acceptance of infant oral health information. Methods: The study used a prospective cohort design to examine the effect of prenatal education …

Ada News - 04/19/2010, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Ada News - 04/05/2010, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Mmp-9/Timp-1 Imbalance Induced In Human Dendritic Cells By Porphyromonas Gingivalis, Ravi Jotwani, Sridhar V K Eswaran, Surinder Moonga, Christopher W Cutler

Faculty, Staff and Student Publications

Matrix metalloproteinase-9 (MMP-9) cleaves collagen, allowing leukocytes to traffic toward the vasculature and the lymphatics. When MMP-9 is unregulated by tissue inhibitor of metalloproteinase-1 (TIMP-1), this can lead to tissue destruction. Dendritic cells (DCs) infiltrate the oral mucosa increasingly in chronic periodontitis, characterized by infection with several pathogens including Porphyromonas gingivalis. In this study, human monocyte-derived DCs were pulsed with different doses of lipopolysaccharide of P. gingivalis 381 and of Escherichia coli type strain 25922, as well as whole live isogenic fimbriae-deficient mutant strains of P. gingivalis 381. Levels of induction of MMP-9 and TIMP-1, as well as interleukin-10 (IL-10), …

Professional Product Review Vol. 5 No. 2, American Dental Association, Council On Scientific Affairs

Professional Product Review

A user-friendly newsletter from the ADA Council on Scientific Affairs offering scientifically sound, unbiased, and clinically relevant information to member dentists about professional dental products tested by the ADA. This collection is historical and may not reflect current standards. For up-to-date information contact the ADA.

J Am Coll Dent 2010 77 2

Journal of the American College of Dentists

The Journal of the American College of Dentists (JACD) publishes scholarly articles, editorials, essays, and reflections addressing the ethical, professional, and social dimensions of dentistry. The Journal serves as a forum for advancing ethics, professionalism, leadership, and excellence within the dental community. By fostering dialogue across disciplines and perspectives, JACD provides readers with insights that encourage ethical, professional practice, lifelong learning, and service to the public, reinforcing dentistry’s commitment to advancing oral healthcare and the common good.

Cementoblastic Response To High Vs. Low Level Of Mechanical Force In Vitro, Natalie Nicole Mullally

Master's Theses (2009 -)

One of the possible complications of orthodontic treatment is apical root resorption. During orthodontic treatment, as the teeth are being moved, the alveolar bone is continually being modeled to accommodate the teeth. This process activates specific cells that are responsible for bone resorption and can have the unwanted effect of resorbing the apex of the tooth root adjacent to the bone. It is unclear exactly what aspects of orthodontic treatment may trigger the resorptive process. A positive correlation, however, between root resorption and mechanical loading applied during orthodontic tooth movement has been established implicating orthodontic treatment in this adverse effect. …

Bondable Lingual Spur Therapy To Treat Anterior Open Bite, Elissa Joy Mcrae

Master's Theses (2009 -)

The purpose of this study was to evaluate the effect of bondable lingual tongue spurs (BLTS; Tongue Tamers®, Ortho Technology, Tampa, FL) on measures of overbite and incisor position in a sample of anterior open bite subjects who had either a digit-sucking habit or an anterior tongue posture problem. Patient acceptance of the spurs was also evaluated. BLTS were placed on all maxillary and mandibular incisors of 12 subjects (mean age 13.9 years) with anterior open bite. Dental casts and lateral cephalometric radiographs were taken pre-treatment (T1) and after 6 months of lingual spur treatment alone (T2). Overbite and overjet …

An In Vitro Comparison Of The Setting Of Mta With And Without The Application Of A Moist Cotton Pellet, Craig Darrell Johnson

Master's Theses (2009 -)

Introduction: The purpose of this study was to compare the setting of MTA with and without the application of a moist cotton pellet. Methods: Fifty samples of MTA were mixed according to manufacturer’s instructions, placed with an amalgam carrier, and condensed with a plugger into a custom metal block with a well depth of 3.5 mm. Twenty-five of the MTA samples had a moist cotton pellet placed in contact with MTA mixture and twenty-five MTA samples had no moist cotton pellet in contact with the MTA mixture. The samples were placed in 100% humidity at 37°C and evaluated for penetration …

Bonding With Self-Etching Primers - Pumice Or Pre-Etch? An In Vitro Study, Ian J. Fitzgerald

Master's Theses (2009 -)

The objective of this study was to compare the shear bond strengths (SBS) of orthodontic brackets bonded with self-etching primer using different enamel surface preparations.

A 2-by-2 factorial study design was used. Sixty human premolars were harvested, cleaned and randomly assigned to four groups (n=15/group). Teeth were bathed in saliva for 48 hours to form a pellicle. Treatments were assigned as follows: Group 1 was pumiced for 10 seconds and pre-etched for five seconds with 37% phosphoric acid before bonding with self-etching primer (Transbond Plus). Group 2 was pumiced for ten seconds before bonding. Group 3 was pre-etched for five …

Bracket Bond Strength Effects Of Incorporation Of Novamin Into An Orthodontic Bonding Resin, Jeffrey Waterhouse

Master's Theses (2009 -)

Despite advances in caries research and the development of protective mechanisms and materials, orthodontic white spot decalcification remains a significant problem. Increased plaque buildup around orthodontic appliances, combined with inadequate hygiene and a susceptible patient, can lead to unesthetic demineralized lesions in enamel.

Relatively new to the arena of caries prevention, NovaMin, a bioactive glass, has shown some promise in areas of remineralization of early lesions, protection against acidic challenge, and has demonstrated antiplaque properties. This study explored a new application of the material, incorporation into an orthodontic bonding composite resin. Objectives of the study were: to determine if the …

Candida Albicans Adhesion And Biofilm Formation On Phosphated And Non-Phosphate Containing Poly(Methylmethacrylate) Polymers, Kathryn Elizabeth Ryan

Master's Theses (2009 -)

Denture-induced stomatitis is prevalent among prosthesis users, particularly the elderly and institutionalized where it has been estimated to be present in over 60-65% of denture wearers. Treatment of this clinical condition is problematic due to incomplete disinfection of the acrylic surface and rapid microbial re-colonization. Moreover, ingestion or aspiration of pathogens in denture plaque exposes the elderly and immunocompromised to unexpected infections.

Acrylic polymers have generally been used to replace missing teeth and periodontal tissues in edentulous or partially dentate patients. Currently, edentulous adults in the US population are common, with complete edentulism greater than 41% among Americans aged 65 …

Light-Activation Influence On The Thermal Analysis Of A Resin-Modified Glass-Ionomer, Raksha Srinivas

Master's Theses (2009 -)

The acid-base and light polymerization reactions in resin modified glass ionomers (RMGI) have been shown to compete and possibly inhibit one another during early RMGI development. Earlier beginning times of light polymerization initiation may limit the acid-base reaction and if time allowed for the acid-base components to react is increased, the extent of light cure reaction may be lesser. The thermal behavior of a commercially available RMGI was investigated in relation to a light initiation regimen using a differential scanning calorimeter (DSC). The relationship between delay in light initiation or no light initiation and the resultant set matrix of the …

Application Of Mechanical Vibration To Modulate Orthodontic Tooth Movement (Otm) In Mice, Andrew Rummel

Master's Theses (2009 -)

Purpose: The purpose of this study was to use micro CT to evaluate the effect of mechanical vibration on orthodontic tooth movement (OTM) in mice. Materials and Methods: Thirty-six mice (C57BL/6, 20 weeks old, male) were randomly divided into four groups: spring/vibration (SV), spring only (S), vibration only (V), control (C). A nickel-titanium (NiTi) spring was fabricated and inserted bilaterally between the maxillary 1st molars, delivering an initial force of 20 grams. From day 0, mechanical vibration (4Hz frequency, 20micron displacement, 5 min per session duration) was applied to the left maxillary 1st molar every three days for 3 weeks …

Incidence Of Removable Partial Denture Types In Eastern Wisconsin, Deo K. Pun

Master's Theses (2009 -)

Aim: This study was designed to investigate patterns of tooth loss in patients receiving removable partial dentures.

Materials and Method: A point and shoot digital camera was used to collect 1502 digital images of cases at 5 dental laboratories in the eastern portion of the state of Wisconsin. Any case presenting to one the dental laboratories requesting a RPD was included. Two photographs were taken of each case. The first photograph was taken immediately upon arrival to the lab while the second photograph was taken immediately prior its first departure. A calibrated investigator analyzed all the photographs for Kennedy classification, …

Dental Maturity Amongst Various Vertical And Sagittal Facial Patterns, Rashna H. Sukhia, Mubassar Fida

Section of Dental-Oral Maxillofacial Surgery

OBJECTIVE: To compare the mean dental maturity amongst three vertical facial patterns (short, average and long anterior facial heights) and also amongst two sagittal facial patterns (skeletal class I and II) in orthodontic patients.

STUDY DESIGN: Cross-sectional analytical study.

PLACE AND DURATION OF STUDY: The Aga Khan University Hospital, Karachi, from August to October 2008.

METHODOLOGY: Data was retrospectively retrieved from pretreatment orthodontic records of patients who visited the orthodontic clinic. The sample was divided into three vertical groups, namely short, average and long anterior facial types, and two sagittal groups, namely skeletal class I and II. Dental development was …

T-786c Polymorphism Of The Endothelial Nitric Oxide Synthase Gene And Neuralgia-Inducing Cavitational Osteonecrosis Of The Jaws, Charles J Glueck, Robert E Mcmahon, Jerry E Bouquot, Naseer A Khan, Ping Wang

Faculty, Staff and Student Publications

OBJECTIVE: We hypothesized that, similar to idiopathic hip osteonecrosis, the T-786C mutation of the endothelial nitric oxide synthase (eNOS) gene affecting nitric oxide (NO) production was associated with neuralgia-inducing cavitational osteonecrosis of the jaws (NICO). DESIGN: In 22 NICO patients, not having taken bisphosphonates, mutations affecting NO production (eNOS T-786C, stromelysin 5A6A) were measured by polymerase chain reaction. Two healthy normal control subjects were matched per case by race and gender. RESULTS: Homozygosity for the mutant eNOS allele (TT) was present in 6 out of 22 patients (27%) with NICO compared with 0 out of 44 (0%) race and gender-matched …

Gender Trends In Dental Leadership And Academics: A Twenty-Two-Year Observation, Judy Chia-Chun Yuan, Damian J. Lee, Suchada Kongkiatkamon, Sasha Ross, Soni Prasad, Anne Koerber, Cortino Sukotjo

School of Dentistry Faculty Research and Publications

The purpose of this study was to examine gender disparities in dental leadership and academics in the United States. Nine journals that represent the dental specialties and high published impact factors were selected to analyze the percentage of female dentists’ first and senior authorship for the years 1986, 1990, 1995, 2000, 2005, and 2008. Data on appointment status and female deanship were collected from the American Dental Association (ADA) survey, and the trends were studied. The proportion of female presidents in ADA-recognized specialty organizations was also calculated. Overall, the increase in first female authorship was not statistically significant, but the …