Dentistry Commons^™

3d Printing In Restorative Dentistry, Sucharu Ghosh, Mahban Zarei, Parul Kumar, Priya Prasannakumar, Patrick Pansoy

Excellence Day

The term 3 D printing is generally used to describe a manufacturing approach that builds objects one layer at a time, adding multiple layers to form an object The presentation aims to provide a comprehensive understanding of the use of 3 D printing technology in restorative dentistry and its potential impact on the field

Human Dental Pulp Stem Cell Culture Model For Studies On Etiopathogenesis Of Nonsyndromic Cleft Lip With Or Without Cleft Palate Anomaly, Tyler Starley, Jonathan Starley, Harrison Truman

Excellence Day

Nonsyndromic cleft lip with or without cleft palate (NSCLP) occurs approximately in 1 of 700 live births. It has a serious impact on a patient during the whole life. It was shown that it can be prevented by supplementation of folic acid. However, much more needs to be known about etiopathogenetic factors and molecular mechanisms leading to NSCLP in order to personalize its prevention. Basic science information on etiology and pathogenesis of NSCLP was obtained from animal experiments. Clinical studies and trials showed efficacy of prevention by folic acid supplementation. A cell culture model is needed for studies on cellular …

Conventional Vs Digital Impressions, Vinitha Gopal-Murthy, Mirna Merhi-Boghossian, Geet Shukla

Excellence Day

Summary: A dental impression is a negative replica of the hard and soft tissues of the oral cavity. Conventional impressions help make dental casts which are used for diagnostic and therapeutic purposes. Digital impression involves a 3D intraoral scanning, which is processed by the impression involves a 3D intraoral scanning, which is processed by the computer to generate a virtual replica of the tissues in the mouth. In siloxanes, poly sulfides, addition and condensation silicones are used. Digital impressions can be a closed system like CEREC, that relies on one manufacturer and technology for CAD/CAM procedures or open systems like …

Comparison Of Various Post-Systems In Endodontically Treated Teeth, Viraj Ketkar, Hemal Pandya, Fariba Yaghoobi

Excellence Day

Summary: This study aims to compare various post-systems used in endodontically treated teeth. A comprehensive literature review was conducted to identify studies that compared different post systems in endodontically treated teeth. The inclusion criteria included studies comparing two or more post-systems regarding clinical and/or radiographic outcomes. The studies included in the review evaluated different types of post systems, including prefabricated metal posts, custom-made metal posts, fibre-reinforced posts, and zirconia posts. The outcomes evaluated included retention rates, fracture rates, and marginal adaptation. Cast posts offer customization benefits but need multiple appointments, while prefabricated posts are widely used for their various material, …

The Effects Of Cigarette Smoke On Sars-Cov-2 Infection In The Oral Cavity – A Preliminary Literature Review, Youyoung Min

Excellence Day

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been suggested to replicate and be found in the oral cavity. The objective of this preliminary literature review is to determine the effects of cigarette smoke on the risk of SARS-CoV-2 infection in the oral cavity, and the risk for the overall health. SARS-CoV-2, which causes coronavirus disease 2019 (COVID-19), uses the ACE2 receptor and protease TMPRSS2 for entry into host cells. The cigarette smoke condensates upregulates these receptors in human gingival epithelial cells. Because smoking can alter expression of COVID-19 viral entry genes, smokers are more susceptible to SARS-CoV-2 infection. Several …

Sex Differences In The Immune Response To Chronic Periodontitis, John Huang, Amy Tsai, Ina Stelzer, Dorien Feyaerts, William Choi, David Vang, Edward Ganio, Dyani Gaudilliere, Brice Gaudilliere, Xiaoyuan Han

Excellence Day

Chronic Periodontitis (ChP) is an inflammatory condition that results from oral dysbiosis and host immune dysfunction. Epidemiologic evidence has shown that men are more susceptible to ChP than women. Despite gender differences in behavior and socioeconomic status influencing oral health, the biological sex-associated immunological mechanisms underlying the pathogenesis of ChP are unclear. The objective of this study is to identify sex differences in the immune responses to chronic periodontitis.

The Effects Of Cigarette Smoke On Sars-Cov-2 Infection In Human Gecs, Kaitlyn Liu, Harmony Matshik Dakafay, David Ojcius, Cassio Silva

Excellence Day

A large body of evidence shows the harmful effects of cigarette smoke to oral and systemic health. Recently, a link between smoking and susceptibility to coronavirus disease 2019 (COVID-19) was proposed. Here, we examined the effects of cigarette smoke on SARS-CoV-2 infection in human gingival epithelial cells (GECs) to better understand the mechanisms involved in SARS-CoV-2 infection in cells of the oral cavity.

Assessment Of Mandibular Plane Changes Using Conventional Versus Miniscrew-Assisted Rapid Palatal Expansion In Adolescents, Michael Ricupito, Daniel Vorhees, Derek Skousen

Excellence Day

The objective of this study was to assess the cephalometric and transversal changes in growing patients (adolescents) using two different types of maxilla expanders: conventional rapid palatal expander (RPE) and miniscrew-assisted rapid palatal expander (MARPE). Our null hypothesis is that there are no significant differences between the two groups for the molar inclination, maxilla expansion amount, and mandibular plane changes.

Biomarkers Of Orthodontic Tooth Movement, Max Kazantcev, Kamal Thapaliya, Marie Tolarova, Miroslav Tolar

Excellence Day

Orthodontic tooth movement leads to remodeling of periodontal ligament, alveolar bone, and gingiva. Tooth movement is characterized by bone deposition at sites of tension and bone resorption at pressure sites. Due to a sterile inflammatory process in the PDL space, a flow rate of gingival crevicular fluid (GCF) is increased and its composition is modified. Various cell-signaling pathways are activated, which ultimately stimulate PDL turnover. Biochemical and cellular processes associated with orthodontic tooth movement may be better understood if we study changes of specific biomarkers in GCF during orthodontic therapy. Such information can be used clinically to choose a proper …

In-Vitro Composite Surface Analysis Using Foru Polishing Systems A Sem Study, Shreya Nerli

Excellence Day

To evaluate the effect of four polishing methods on the surface gloss of a composite.

Shared Decision Making In Scaling And Root Planing, José Verdugo, Lory Laughter, David W. Chambers

Excellence Day

Estimate the patient participation in decisions commonly arising in scaling and root planing as functions of the professionals’ preferences of dental hygienists, typical situations in this procedure, common approaches to patient interaction, and the interaction of these factors.

Diabetes, Periodontitis And The Oral Microbiome, Madison West, Kaitlin Liautaud, Charles Hunter Pitts, Michael Ricupito, Joshua Cho

Excellence Day

The association between diabetes mellitus and periodontitis has been studied thoroughly. However, the role of the oral microbiome in linking these two diseases still is not clear. The objective of this literature review is to search the current studies on oral dysbiosis in the two diseases and find out whether the oral microbiome could be a possible biomarker indicating diabetes in periodontal patients.

Cbct Analysis Of Root Resorption In Orthodontic Patients With Short Root Anomaly, Sani Zaidi, Kaiyuan Xu, Heesoo Oh, Jonas Bianchi

Excellence Day

The objective of this study was to evaluate the amount of root resorption after orthodontic treatment in patients with Short Root Anomaly (SRA) in comparison with control patients using Cone Beam Computed Tomography (CBCT). We hypothesized that patients with SRA present more susceptibility to root resorption during orthodontic treatment when compared to the normal population.

Covid-19 Wastewater Project: Validating Sars-Cov-2 Detection Techniques, David Kim, David Vang, David Ojcius, Der Thor

Excellence Day

This research was done to validate and test the current viral RNA detection techniques and to determine sensitivity and optimal temperature of RT-qPCR technique.

Relationship Between Cervical Vertebral Maturation And Chronological Age: A Mixed Longitudinal Study, Sudhashree Lingam, Garima Shrestha, Vijaylaxmi Nag, Aditi Ghosh, Hanisha Pasupulate, Heesoo Oh

Excellence Day

The cervical vertebrae have been proposed as a method of determining skeletal maturation.This study aimed to evaluate the relationship between chronologic age and the individual skeletal maturity as assessed by means of the cervical vertebral maturation (CVM) method.

The Role Of Inflammation In Epithelial-Mesenchymal Transition In Oral Squamous Cell Carcinoma: Literature Review, Preliminary Data, And Proposal Of Experiments, Rachel Choi, Jisoo Kim, Adria Frazier, Takahiro Chino

Excellence Day

The epithelial-mesenchymal transition (EMT) is a trans-differentiation process of epithelial cells into motile mesenchymal cells. It plays an integral role in embryonic development, wound healing and cancer progression. During EMT, epithelial cells lose their cellular polarity due to the loss of intercellular adhesion and acquire migratory and invasive characteristics associated with mesenchymal cells. EMT is tightly regulated by a number of distinct molecular processes which allow its initiation and progression to completion. These processes include activation of transcription factors, expression of specific cell-surface proteins, reorganization and expression of cytoskeletal proteins, production of extracellular matrix-degrading enzymes and changes in the expression …

Managing Patient Expectations With Implant Treatment, Daniel B. Kamran, Mark Booth Dds, Eduardo Gonzalez Dds, Ed Shaw Dds

Excellence Day

This patient came to University of the Pacific, Arthur A. Dugoni School of Dentistry to get implants and implant crowns to improve his smile, replacing his upper partial denture. Different approaches were made by the faculty to arrive at best outcomes, which took four years for the patient to receive the treatment he wanted. This abstract will further detail how the treatment was conducted and the results afterwards.

Rapid Placement And Anatomical Sculpting Of Hardened Posterior Composite, Patrick Roetzer, Mahek Pipalia, Krunali Kapadia

Excellence Day

Posterior composites have long had a reputation for being difficult and time consuming in clinical practice. In addition to this reputation, it has been noted that recurrent caries and in general failure of these restorations prematurely has been a problem. Relative to amalgams, posterior composites have vexed even good clinical dentist. This video presentation illustrates techniques that not only save time but also create more predictable high-quality restorations.

A Modified “Wound Healing” And Hypoxia Model In Vitro, Schuyler G. Tang, Isabel Kwon, Marie M. Tolarova, Mirek Tolar

Excellence Day

Closing a wound may resemble some aspects of fusion of embryonic processes during development of face. In addition, both are sensitive to oxygen supply.

Effect Of Folate On Endoplasmic Reticulum Stress Caused By Hypoxia, Paul Kim, Shub Dhillon, Mahsa Mortazavi, Marie M. Tolarova, Mirek Tolar

Excellence Day

Endoplasmic reticulum (ER) stress is involved in the pathogenesis of congenital cardiac defects, intrauterine growth restriction, craniofacial anomalies, and many common diseases. The purpose of this study was to test if folic acid (FA) can mitigate ER stress or improve recovery of cells from ER stress.

Biomarkers Of Orthodontic Tooth Movement, Ellie Schwartz, Shubdeep Kaur, Mahsa Mortazavi, Marie M. Tolarova, Mirek Tolar

Excellence Day

Orthodontic tooth movement is made possible by remodeling of the alveolar bone process. Bone remodeling is carried out by cellular activities of osteoclasts, osteoblasts, and osteocytes. This in turn is regulated by a number of extracellular factors including growth factors, cytokines, chemokines, hormones and biomechanical force. This review is focused on chemical biomarkers characterizing orthodontic tooth movement.

Geometric Morphometric Shape Assessment Of Juvenile Mandibles, Tiffany Tran, Vicki Lo, Hee Soo Oh, Gary D. Richards

Excellence Day

OBJECTIVES: We explore three-dimensional data to delineate idiosyncratic and progressive growth variation in 6.0-8.0 year old mandibles (n=45).

Variation In And Assessment Of Inferior Alveolar Nerve Block Landmarks In Children And Adolescents, Soi Park, Younjin Lee, Younyoung Lee, Tiffany Tran, Gary D. Richards

Excellence Day

OBJECTIVES: In earlier work (Lambert et al., 2017) we demonstrated the efficacy of new landmarks for inferior alveolar nerve (IAN) block injections. While the latter study focused on adult morphology, the landmarks were shown to be effective in cases where the M³/₃ were present but unerupted. Based on these result a question arose as to their applicability of the landmarks to children and adolescents, given the known changes in mandibular foramen position during growth. Here we quantify the position of the mandibular foramen relative to standard landmarks during growth and assess the new landmarks applicability for IAN …

Shear Bond Strength Of Nine Dual Cured Build-Up Materials And A Light-Curing Adhesive System On Dentin, Deepali Malla, Karen Schulze, Patrick Roetzer

Excellence Day

The purpose of this study was to measure the shear bond strength of nine different commercially available dual cured core build-up materials on human dentin in conjunction with a light curing adhesive system. The null hypothesis was that there is no statistical significant difference among the core build-up systems.

Root Analogue Implant Creation: Establishing Procedures For The General Dentist, Alicia Hazdovac, Sarah Osborne, Gary D. Richards

Excellence Day

The possibility of replacing damaged teeth with custom-made root analogue implants was initially suggested around 1969 and reintroduced by Lungren et al. in 1992. The latter authors created custom implants in titanium and reported good osteointegration and aesthetic results. Following this effort there has been an increasing focus on custom root analogue implants as a replacement for ‘screw-type’ implants. Given the availability of software to manipulate 3D image data and the rapid rise of 3D printing technology, the question arises as to whether a general dentist can produce their own implants. Here we test the feasibility of practitioners producing custom …

The Role Of Aryl Hydrocarbon Receptor (Ahr) Signaling Pathway In Oral Squamous Cell Carcinoma (Oscc): Preliminary Results., Renee Lee, Cui Xu, Leticia Ferreira, Ana Carolina Morandini, Erivan Ramos-Junior

Excellence Day

OBJECTIVES: A large number of experimental and clinical studies suggest that the origin of oral squamous cell carcinoma (OSCC) is linked to environmental carcinogenesis (tobacco, alcohol). Among these environmental factors, cigarette smoking is the most studied and has been associated with increased susceptibility to OSCC by activating signaling pathways responsible for cancer initiation and progression. Besides nicotine, cigarette smoke also contains aryl hydrocarbon receptor (AhR) agonists, such as dioxin and benzo(a)pyrene. Aberrant AhR expression and AhR pathway activation are involved in several types of cancer. However, the relationship between AhR pathway activation and oral cancer progression is still unclear.

Genes Associated With Mandibular Prognathism In The Chinese Population, Jacqueline Payne, Marie Tolarova M.D., Ph.D., D.Sc.

Excellence Day

Mandibular prognathism (MP) is the relationship of the mandible anteriorly positioned in relation to the cranial base. The prevalence of MP in Asians is estimated to be 15%, whereas American and European descent exhibit a 5% prevalence. Orthodontic treatment is lengthy and challenging, and severe cases require surgical intervention. However, when a treatment is planned well, the outcomes are predominantly successful. It has been known that genetics are involved in the etiology of prognathism and that greater genetic contribution corresponds to greater challenges to treatment. Thus, there is a desire to determine genes involved in the etiology of prognathism.

Socio-Economic Factors That May Contribute To Etiology Of Orofacial Clefts., Shubdeep Kaur, Mahsa Mortazavi, Geethapriya Kumar, Marie M. Tolarova

Excellence Day

Association of socio-economic status (SES) with congenital anomalies and diseases has been studied for many years. Under the umbrella of SES are several factors and they vary in different parts of the world due to differences in climate, ethnicity, and culture.

The purpose of this systematic review was to determine associations between various risk factors related to SES and prevalence of orofacial clefts (OFC).

Orofacial Clefts In The Middle Eastern Countries – A Systematic Review, Mahsa Mortazavi, Marie M. Tolarova

Excellence Day

The purpose of this study was to determine the prevalence of orofacial clefts (OFC) in the Middle East. Recent studies of etiology of OFC in populations of different countries characterized by a specific cultural, religious, or socioeconomic status revealed that different environmental and genetic factors may participate in their etiology.

Distribution Of Malocclusions In Middle East Countries: A Systematic Review., Mahsa Mortazavi, Marie M. Tolarova

Excellence Day

High prevalence, multifactorial etiology and the effect on the esthetic, function and quality of life, make the malocclusions as a subject of debate for many years. Regarding the important role of malocclusion in treatment approaches, policy making in health organizations and understanding the etiology factors, this literature review was performed with the purpose of determining the prevalence and distribution of malocclusion in region of the Middle East.