Dentistry Commons^™

The Influence Of Biofilm On The Antifungal Activity Of Amine Oxide, Jonathan Michael Hart

Theses and Dissertations (ETD)

Denture-related stomatitis (DRS) is the most common oral disease affecting denture wearers today, and is characterized by inflammation of the denture bearing mucosa. In a search through historical dental literature for the most often suspected culprit of DRS, one will repeatedly find first listed the fungus Candida albicans. While C. albicans can be isolated from the fitting surfaces of dentures, and the supporting mucosa of patients suffering from DRS, it is also found in the oral cavity of 65% of the human population—most of which is free from oral disease. A truth puzzling to investigators, the discovery of a self-produced, …