Dentistry Commons^™

Immediate Effect Of Complete Denture Occlusal Errors On Masticatory Muscle Emg Activity In Denture Wearers: A Pilot Study, Swati Ahuja

Theses and Dissertations (ETD)

In the last three decades, little scientific progress has been seen in relation to the occlusal aspects in complete dentures. Equal distribution of loading forces to the edentulous denture foundation is an important factor affecting stability, patient comfort and acceptance of complete dentures. Also, understanding the functional behavior of masticatory muscles for complete denture wearers is important for diagnosing and planning the clinical treatment.

The purpose of the present study was to determine the effect of unilateral and bilateral occlusal interferences on the masticatory muscle activity in edentulous patients, and how patients respond to occlusal interferences both physiologically and psychologically …

Effect Of Methamphetamine On Gingival Fibroblast Production Of Matrix Metalloproteinase (Mmp)-2 And -9 And Tissue Inhibitor Of Metalloproteinase (Timp)-1 And -2 In Vitro, Owais Ali Farooqi

Theses and Dissertations (ETD)

Methamphetamine (METH) abuse is associated with "METH mouth" characterized by rampant caries and periodontitis. Matrix metalloproteinases (MMPs) produced by gingival fibroblasts degrade the extracellular matrix (ECM) and play an important role in periodontitis and oral cancer metastasis. There is no information on effects of METH on fibroblast MMP production, or its role in periodontitis or tumor metastasis.

Objective: Determine effect of METH on gingival fibroblast MMP production and activity.

Methods: A human gingival fibroblast cell line was used. METH cytotoxicity was determined by measuring its effects on activity of a mitochondrial enzyme. Cells were cultured ± METH (1x10^-6- …

The Influence Of Biofilm On The Antifungal Activity Of Amine Oxide, Jonathan Michael Hart

Theses and Dissertations (ETD)

Denture-related stomatitis (DRS) is the most common oral disease affecting denture wearers today, and is characterized by inflammation of the denture bearing mucosa. In a search through historical dental literature for the most often suspected culprit of DRS, one will repeatedly find first listed the fungus Candida albicans. While C. albicans can be isolated from the fitting surfaces of dentures, and the supporting mucosa of patients suffering from DRS, it is also found in the oral cavity of 65% of the human population—most of which is free from oral disease. A truth puzzling to investigators, the discovery of a self-produced, …

Use Of Cvm Stages In Assessment Of Young Orthodontic Patients To Estimate Growth Potential, David Justin Sander

Theses and Dissertations (ETD)

Harnessing a patient’s growth to correct parasagittal discrepancies is an important part of Class II correction in orthodontic treatment; however, orthodontists rarely have the opportunity to choose when a patient is referred to them. Diagnostic records can assist the orthodontist in determining how much growth a patient has remaining. The purpose of this retrospective cephalometric study was to determine whether the amounts of in-treatment facial growth differ significantly by sex and by cervical vertebral maturation (CVM) stage. The sample consisted of 133 Class II division 1 patients from a single private practice office treated with a combination of a functional …

Mesiodistal Crown Size In Relation To The Risk And Severity Of Malocclusion, Jon Robert Zang-Bodis

Theses and Dissertations (ETD)

From among numerous potential causes of dental malocclusion, tooth size has been implicated as one factor. Prior studies show that mesiodistally larger teeth increase the risk of malocclusion. The present report extends our understanding by testing for graded responses between crown size and the extent of dental malocclusion. Maximum mesiodistal crown dimensions of all 14 permanent tooth types (excluding third molars) were measured in 207 American white adolescents (routine orthodontic patients), and 10 measures of malocclusion (e.g., rotations, displacements, spacing) were recorded. Analysis of covariance (controlling for sexual dimorphism in tooth size) disclosed (1) significant positive associations between …

Differential Stimulation Of Monocytes To Secrete Secretory Leukocyte Protease Inhibitor By Lipopolysaccharide Of Periodontal Pathogens, Jason Todd Primm

Theses and Dissertations (ETD)

Lipopolysaccharide (LPS), or endotoxin, is the major component of the outer surface of gram-negative bacteria. LPS is a potent activator of cells of the immune and inflammatory systems, including macrophages, monocytes, and endothelial cells, and contributes to systemic changes known as septic shock. Each LPS molecule has three regions: oligosaccharide, core, and lipid A. Oligosaccharide is exposed on the cell surface, and lipid A anchors LPS in the outer membrane. Recent studies from our lab demonstrated that LPS of periodontal pathogens suppresses neutrophil's ability to secrete super oxide ions and also shown it to interfere with neutrophil chemotaxis. These factors …