Dentistry Commons^™

Gene Expression Profiles Of Cytokines During Osteogenic Differentiation Of Human Gingiva Derived Mesenchymal Stem Cells, Reem Almashat

Student Theses, Dissertations and Capstones

A thesis submitted to the College of Dental Medicine of Nova Southeastern University of the degree of Master of Science in Dentistry.

Background: Therapeutic management of bone loss in the craniofacial region as a consequence of trauma, surgery or congenital malformations presents a clinical challenge. Mesenchymal stem cells (MSCs), due to their inherent plasticity, are potential candidates for cell based therapies for the repair and reconstruction of craniofacial bone tissue. Guided differentiation of stem cells to osteogenic precursors is marked by spatio-temporally regulation of gene expression profiles including that of transcription factors, cytokines, extracellular matrix proteins, enzymes and several signaling …

Comparison Of The Effectiveness Of Mechanical And Chemical Procedures To Decontaminate Titanium Disks And To Promote Osteoblast Attachment, Flavia Goncalves

Student Theses, Dissertations and Capstones

Objective: This study was conducted to determine the effectiveness of physical and mechanical disinfection of P. gingivalis from implant disks and to evaluate bone cells growth and attachment to the disks. Background. Each year, over three million of Americans replacing missing teeth with dental implants. An inflammatory process around an implant that causes bone loss, characterizes peri-implantitis, first diagnosed in the 1980s. The prevalence is approximately 22%. To date, no treatment protocol of peri-implantitis has been proposed. Methods. 207 implants disks. Four different implant surfaces utilized. Disks were contaminated by p. gingivalis and consequentially disinfected by physical means (spraying prophy …

Evaluation Of Critical Parameters Of Low Level Laser Irradiation On Human Osteoblast Cell Proliferation And Differentiation, Samuel Dean Waddoups

Student Theses, Dissertations and Capstones

Abstract

Orthodontic tooth movement is a biological response to a mechanical force. One of the challenges in orthodontics is obtaining desired tooth movement during treatment. Accelerating tooth movement and decreasing demands on anchorage can reduce treatment times and overall satisfaction for patient and doctor. Low-level laser therapy (LLLT) is emerging as a technology that may decrease orthodontic treatment time. Many in vitro and in vivo studies have reported the effects of low level lasers at random time points and energy densities. None of the studies have optimized the dose required for osteoblast proliferation and differentiation. The purpose of this study …