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Articles 1 - 30 of 71
Full-Text Articles in Dentistry
Agenda (Pdf), School Of Dentistry
Agenda (Pdf), School Of Dentistry
LSU School of Dentistry Research Day
Agenda for the LSUSD Research Day held June 5, 2026.
Lycopene, Race And Periodontitis: Disparities In Older Adults, Katherine Kwong, You Lu, Zhuo Huan Li, Susu Luo, Zhaoyu Huang, Zhong Chen, Na Zhao, Tung Sung Tseng
Lycopene, Race And Periodontitis: Disparities In Older Adults, Katherine Kwong, You Lu, Zhuo Huan Li, Susu Luo, Zhaoyu Huang, Zhong Chen, Na Zhao, Tung Sung Tseng
School of Public Health Faculty Publications
Background Periodontitis is a severe gum disease that can be an indicator of other health conditions such as cardiovascular disease and diabetes. Lycopene has been suggested as an adjunct therapy for periodontitis. This study aims to investigate the association between insufficient lycopene intake and the risk of Periodontitis among non-Hispanic White (NHW) and non-Hispanic Black (NHB) older adults. Methods The study included 1,227 adults aged 65–79 years from the National Health and Nutritional Examination Survey (2009–2014). Total lycopene intake from daily diet was studied with age, race, marital status, smoking status, BMI, diabetes, sex, and education as independent variables in …
Conservative Vs Invasive Interventions For Temporomandibular Disorders–An Executive Summary Of The Clinical Practice Guideline, Gary D. Klasser, Charles S. Greene
Conservative Vs Invasive Interventions For Temporomandibular Disorders–An Executive Summary Of The Clinical Practice Guideline, Gary D. Klasser, Charles S. Greene
School of Dentistry Faculty Publications
This guideline is based on the International Association for Dental, Oral, and Craniofacial Research (IADR) list of keypoints for the diagnosis and management of TMDs. Clinical Question: Are conservative reversible therapies more effective for TMDs as compared to invasive and irreversible interventions?
Induction Of Myelopoiesis By Candida Dubliniensis Drives Protective Trained Immunity Against Sepsis In A Card9-Dependent Manner, Shannon Esher Righi, Elizabeth A. Lilly, Amanda J. Harriett, Patrick W. Daly, Maryjane Jones, Chad Steele, Mairi C. Noverr, Paul L. Fidel
Induction Of Myelopoiesis By Candida Dubliniensis Drives Protective Trained Immunity Against Sepsis In A Card9-Dependent Manner, Shannon Esher Righi, Elizabeth A. Lilly, Amanda J. Harriett, Patrick W. Daly, Maryjane Jones, Chad Steele, Mairi C. Noverr, Paul L. Fidel
School of Dentistry Faculty Publications
Trained immunity is a long-term functional reprogramming of innate cells that allows for the formation of immune memory akin to adaptive responses, but with a more rapid nonspecific response. We recently identified an anti-inflammatory trained immunity response, termed trained tolerogenic immunity (TTI), induced by low virulence Candida dubliniensis, that protects against acute lethal polymicrobial sepsis via myeloid-derived suppressor cells (MDSCs). Trained immunity and MDSCs arise following hematopoietic stem and progenitor cell (HSPC) expansion in the bone marrow. Here, we show that C. dubliniensis induces inoculum-dependent protection and HSPC expansion, whereas depletion of HSPCs following C. dubliniensis immunization abrogates protection. We …
Dental Microwear And Diets Of Late Miocene Primates From Rudabánya, Hungary, Peter S. Ungar, Anna K. Wilcox, David R. Begun
Dental Microwear And Diets Of Late Miocene Primates From Rudabánya, Hungary, Peter S. Ungar, Anna K. Wilcox, David R. Begun
School of Dentistry Faculty Publications
Objectives: This study focuses on a dental microwear texture analysis of European pliopithecids and dryopithecins from the Miocene primate site of Rudabánya, Hungary. The goal is to determine whether these taxa, found in part together in the same deposits, differed in their food preferences, or at least consumed, on a daily basis, in a manner that might have facilitated sympatry. Materials and Methods: Here we report on a molar surface texture analysis of all available fossil primates from Rudabánya that preserve antemortem microwear. This includes both Anapithecus hernyaki (n = 14) and Rudapithecus hungaricus (n = 5, including one from …
Understanding And Predicting Flossing Behavior In A Rural Appalachian Community Using The Multi-Theory Model, Rahib K. Islam, Manoj Sharma, Amanda H. Wilkerson, Bradford Layman, Clyde Dunn, Shamima A. Somi, Ratnesh Sharma, Karen Gruszynski, Syed S. Quadri, Vinayak K. Nahar, Robert E. Davis
Understanding And Predicting Flossing Behavior In A Rural Appalachian Community Using The Multi-Theory Model, Rahib K. Islam, Manoj Sharma, Amanda H. Wilkerson, Bradford Layman, Clyde Dunn, Shamima A. Somi, Ratnesh Sharma, Karen Gruszynski, Syed S. Quadri, Vinayak K. Nahar, Robert E. Davis
School of Medicine Faculty Publications
Effective flossing is essential for preventing periodontal disease. However, in a rural Appalachian community, adherence to flossing routines remains low, contributing to significant oral health disparities. The purpose of this study was to conceptualize intention of initiation and sustenance of flossing behaviors using the multi-theory model (MTM) of health behavior change. A cross-sectional survey was administered to individuals recruited from a shopping mall in rural Appalachia. The MTM constructs were measured and data were analyzed using multiple linear regression models. Of the 228 participants, 55% did not floss daily. Behavioral confidence (β = 0.571, p < 0.001) was a significant predictor for the intention of initiation of flossing among non-daily flossers, while emotional transformation (β = 0.377, p = 0.836) significantly explained sustenance among non-daily flossers. For daily flossers, changes in the physical environment (β = 0.432, p = 0.003) significantly predicted the intention of initiation of flossing, whereas emotional transformation (β = 0.344, p = 0.008) and practice for change (β = 0.594, p < 0.001) significantly predicted sustenance of flossing behavior. The MTM appears to be a robust framework for understanding and predicting flossing behaviors in rural Appalachian populations. Interventions designed to enhance behavioral confidence, physical environment changes, emotional transformation, and practice for change could improve flossing adherence. Further research should explore these constructs to develop targeted public health strategies.
Effect Of Margin Thickness And Cement Gap On The Fabrication And Fit Accuracy Of Additively Manufactured Crowns In Definitive Resins With Different Filler Content, Mustafa Borga Dönmez, Gülce Çakmak, Çiğdem Kahveci, Amir H. Nejat, Burak Yilmaz, Pinar Altinci
Effect Of Margin Thickness And Cement Gap On The Fabrication And Fit Accuracy Of Additively Manufactured Crowns In Definitive Resins With Different Filler Content, Mustafa Borga Dönmez, Gülce Çakmak, Çiğdem Kahveci, Amir H. Nejat, Burak Yilmaz, Pinar Altinci
School of Dentistry Faculty Publications
PURPOSE: To evaluate how commercially available composite resins in varying filler content affect the fabrication and fit accuracy (trueness and precision) of additively manufactured (AM) definitive crowns with different margin thickness and cement gaps by comparing them to subtractively manufactured (SM) polymer-infiltrated ceramic crowns. MATERIALS AND METHODS: Two identical unprepared mandibular right first molars were prepared by an experienced prosthodontist for crowns with either 0.5 mm or 1.0 mm chamfer margins, verified using silicone indexes and a periodontal probe, and then digitized with an industrial-grade scanner. These scan files were used to design reference crowns with either 50-µm or 80-µm …
The Effects Of Rubber Dam Clamps On Zirconia Crown Restorations, Haley D. Kessler, Albert F. Mcmullen Iii, Hunter Kortum, Edwin Kee, Thomas E. Lallier
The Effects Of Rubber Dam Clamps On Zirconia Crown Restorations, Haley D. Kessler, Albert F. Mcmullen Iii, Hunter Kortum, Edwin Kee, Thomas E. Lallier
School of Dentistry Faculty Publications
Rubber dam isolation is crucial in providing sterility and a controlled environment when performing root canal therapy. Rubber dam clamps have been controversial due to their rigidity and composition, which is thought to cause damage to zirconia full coverage crowns. This study evaluated three types of zirconia crowns anterior 5Y, premolar 4Y, and molar 3Y to assess their resistance to damage from rubber dam clamps. Of the 30 total zirconia crowns that were tested for damage following the usage of rubber dam clamps, no fractures or chips were observed. There was no significant difference between the negative control group, and …
Evaluation Of Different Resin-Based Barriers In Reducing Microleakage In Restoratively Compromised Posterior Teeth During Rubber Dam Isolation: An Ex Vivo Study, Carolina Becerra, Albert F. Mcmullen Iii, Joon Koh, Thomas E. Lallier
Evaluation Of Different Resin-Based Barriers In Reducing Microleakage In Restoratively Compromised Posterior Teeth During Rubber Dam Isolation: An Ex Vivo Study, Carolina Becerra, Albert F. Mcmullen Iii, Joon Koh, Thomas E. Lallier
School of Dentistry Faculty Publications
Introduction: The rubber dam has been a standard in endodontic practice for over 140 years, providing critical isolation to prevent microbial contamination during root canal therapy. However, studies indicate that microleakage between the rubber dam and tooth structure may still occur, potentially leading to bacterial infiltration. Various resin-based barriers have been introduced to enhance isolation and minimize leakage. This study aimed to evaluate the efficacy of four resin-based barriers in reducing microleakage during endodontic procedures. Methods: Forty extracted human mandibular molars were selected, stored in distilled water, and standardized for experimental conditions. Standard endodontic access was created, and the mesiobuccal …
Comparing Gutta Percha Backfill Leakage Over Multiple Heating Cycles, Hannah Battle, Thomas E. Lallier, Landon Boenke, Albert F. Mcmullen Iii
Comparing Gutta Percha Backfill Leakage Over Multiple Heating Cycles, Hannah Battle, Thomas E. Lallier, Landon Boenke, Albert F. Mcmullen Iii
School of Dentistry Faculty Publications
Introduction: Warm vertical compaction of gutta-percha is a commonly used obturation technique due to the material’s thermoplastic properties. However, gutta-percha in backfill systems is often heated, cooled, and reheated multiple times before use, potentially altering its physical properties. This study investigated whether repeated heat cycling affects the sealing ability of gutta-percha, as measured by coronal dye leakage. Methods: Forty extracted single-rooted human teeth were cleaned, shaped, and randomly divided into four groups (n = 10) based on the number of heating cycles the gutta-percha underwent prior to obturation: Group A (1 cycle), Group B (3 cycles), Group C (5 cycles), …
Agenda (Pdf), School Of Dentistry
Agenda (Pdf), School Of Dentistry
LSU School of Dentistry Research Day
No abstract provided.
A Multi-National Questionnaire-Based Analysis Of Dental Students’ Knowledge Of The Management Of Deep Caries And The Exposed Pulp, Venkateshbabu Nagendrababu, Arindam Dutta, Ana Arias, Aleksandar Jakovljevic, Ahmed Hieawy, Frank C. Setzer, Jugoslav Ilic, Milos Beloica, Meric Karapinar Kazandag, Nandini Suresh, Paul V. Abbott, Raghavendra M. Shetty, Srinivasan Narasimhan, Victoria Sh Yu, Vellore Kannan Gopinath, Ya Shen, Henry F. Duncan
A Multi-National Questionnaire-Based Analysis Of Dental Students’ Knowledge Of The Management Of Deep Caries And The Exposed Pulp, Venkateshbabu Nagendrababu, Arindam Dutta, Ana Arias, Aleksandar Jakovljevic, Ahmed Hieawy, Frank C. Setzer, Jugoslav Ilic, Milos Beloica, Meric Karapinar Kazandag, Nandini Suresh, Paul V. Abbott, Raghavendra M. Shetty, Srinivasan Narasimhan, Victoria Sh Yu, Vellore Kannan Gopinath, Ya Shen, Henry F. Duncan
School of Dentistry Faculty Publications
Introduction and aims: To evaluate knowledge regarding the management of deep carious lesions and exposed pulps among undergraduate and postgraduate endodontic students from ten dental institutions across ten countries, and the impact of operator (material, antibiotic prescription) and patient-related (age, symptoms) factors on their treatment protocols. Methods: An online questionnaire was distributed to evaluate student knowledge of the management of deep caries and exposed pulp related to four clinical scenarios. Simple descriptive statistics were used to describe the data and McNemar tests were employed to identify significant differences between the scenarios. The P-value was set at 5%. Results: A total …
Effect Of Access Cavity Preparation And Cement On The Fracture Load Of Translucent Zirconia Crowns, Andrea Fenton, Amir H. Nejat, Edwin Kee, Xiaoming Xu, Albert F. Mcmullen Iii
Effect Of Access Cavity Preparation And Cement On The Fracture Load Of Translucent Zirconia Crowns, Andrea Fenton, Amir H. Nejat, Edwin Kee, Xiaoming Xu, Albert F. Mcmullen Iii
School of Dentistry Faculty Publications
Purpose: To evaluate the effect of endodontic access hole preparation and choice of luting cement on the fracture resistance of translucent zirconia (5Y) crowns. Materials and Methods: Polymethylmethacrylate (PMMA) dies, representing a prepared maxillary molar tooth, were milled. Translucent zirconia crowns were milled from 5Y (Cercon XTML) zirconia discs and sintered. Forty crowns were divided into four groups (n = 10 per group) based on access hole preparation (accessed, non-accessed) and type of luting cement (resin cement, resin modified glass ionomer (RMGI) cement). Crowns were cemented on the PMMA dies with either resin cement (Panavia SA Cement Universal, Kuraray Noritake …
Effect Of Endodontic Access Preparation On The Retention Of Zirconia Crowns With Temporary Or Permanent Access Hole Restorations: An In Vitro Study, J. Nick Sanders, Amir H. Nejat, Peter Dupree, Edwin Kee, Madeleine E. Raymond, Fred Mcmullen
Effect Of Endodontic Access Preparation On The Retention Of Zirconia Crowns With Temporary Or Permanent Access Hole Restorations: An In Vitro Study, J. Nick Sanders, Amir H. Nejat, Peter Dupree, Edwin Kee, Madeleine E. Raymond, Fred Mcmullen
School of Dentistry Faculty Publications
Objectives: To evaluate the effect endodontic access preparation had on the retention of anterior zirconia crowns after restoring the access hole with temporary versus permanent restorative materials. Methods: 30 anterior zirconia crowns were milled from 5Y-TZP zirconia and bonded to a 3D printed die with resin cement. Crowns were randomly divided into three groups including negative control (NC, n = 10) with no endodontic access preparation; positive control (PC, N = 10) received endodontic access preparation and was restored with a temporary restorative material (Cavit); composite restoration (CR, N = 10) received an endodontic access preparation and then the access …
Ketorolac And Dexamethasone Injection Comparison On Postoperative-Pain In Impacted Mandibular Third Molars Surgery In Pterygomandibular Space: A Randomized Clinical Trial, E. Farokh-Gisour, S. Hajmohamadi, M. Shokrizadeh, S.Y. Shahrbabaki, Homa Kamyabi
Ketorolac And Dexamethasone Injection Comparison On Postoperative-Pain In Impacted Mandibular Third Molars Surgery In Pterygomandibular Space: A Randomized Clinical Trial, E. Farokh-Gisour, S. Hajmohamadi, M. Shokrizadeh, S.Y. Shahrbabaki, Homa Kamyabi
School of Public Health Faculty Publications
Objective: To compare the effects of ketorolac and dexamethasone on postoperative pain in patients who underwent impacted mandibular third molars surgery. Material and Methods: A double-anonymized clinical trial study involving 60 patients with impacted third molars. The samples were randomly divided into two groups by block randomization method: DG: Dexamethasone (8 mg) and KG: Ketorolac (30 mg). The severity of pain was assessed using the visual analog scale and Wong-Baker Faces Pain Rating Scale immediately and during the first to seventh days after the surgery. Results: Among the participants, 65% were female, and the mean age was 40.8 years. The …
The Effect Of Different Surface Treatments On The Roughness, Translucency, And Staining Of 3d-Printed Occlusal Device Materials, Silvia Rojas Rueda, Hanna Sepsick, Mohammed Hammamy, Amir H. Nejat, Edwin Kee, Nathaniel C. Lawson
The Effect Of Different Surface Treatments On The Roughness, Translucency, And Staining Of 3d-Printed Occlusal Device Materials, Silvia Rojas Rueda, Hanna Sepsick, Mohammed Hammamy, Amir H. Nejat, Edwin Kee, Nathaniel C. Lawson
School of Dentistry Faculty Publications
OBJECTIVES: To compare surface treatments (as-printed, optical polish, resin-coated, polished) of two 3D-printed occlusal device materials (KeySplint Soft and NightGuard Flex 2) cured with or without glycerin for surface roughness, translucency, and coffee staining. MATERIALS AND METHODS: Discs (2 mm thick) from two 3D-printed occlusal resins (KeySplint Soft and NightGuard Flex 2) were printed using a DLP 3D printer (SprintRay Pro 95), cleaned (ProWash S), and cured (ProCure 2) with or without glycerin. Some specimens were printed in an optical polish tank. Specimens were either as-printed, resin-coated, or polished. Reference milled (ProArt CAD Splint) and heat-cured (Excel Formula Heat Cure …
Early Childhood Caries And Associated Risk Factors Among Preschool Children In Southeast Iran, Homa Kamyabi, Parisa Kalantari, Azadeh Horri, Fereshteh Abbasi, Mahsa Kalantari
Early Childhood Caries And Associated Risk Factors Among Preschool Children In Southeast Iran, Homa Kamyabi, Parisa Kalantari, Azadeh Horri, Fereshteh Abbasi, Mahsa Kalantari
School of Public Health Faculty Publications
Objective: To determine the prevalence of ECC and evaluate its association with possible risk factors in a group of preschool children in Kerman, Iran. Material and Methods: This cross-sectional study was conducted in Kerman on healthy preschool children (up to 6 years old) in June and October 2021. The children were randomly selected from kindergartens using a clustered sampling method, and their height, weight, dental caries, and occlusion were evaluated. Parents completed a questionnaire assessing feeding habits (breast/bottle feeding) and oral habits during the first two years of life. Data were analyzed by logistic regression and chi-squared test using SPSS …
Impact Of Coronavirus Disease 2019 On Dental Match Residency Applicant Statistics In The United States Of America: A Cross Sectional Analysis, Vinayak M. Joshi, Eswar Kandaswamy, Sivaraman Prakasam, Veerasathpurush Allareddy, Andrew G. Chapple
Impact Of Coronavirus Disease 2019 On Dental Match Residency Applicant Statistics In The United States Of America: A Cross Sectional Analysis, Vinayak M. Joshi, Eswar Kandaswamy, Sivaraman Prakasam, Veerasathpurush Allareddy, Andrew G. Chapple
School of Dentistry Faculty Publications
Background: The purpose of this paper is to do a cross-sectional analysis to evaluate the impact of the Coronavirus Disease 2019 pandemic on Dental Match Residency statistics from the year 2019–2023. Methods: The Dental Match Residency statistics available from the Dental Match website were analyzed from years 2019–2023 to evaluate the impact of pre-pandemic (2019–2020), pandemic (2021, 2022) and post-pandemic year trends (2023). Important trends were evaluated and summarized using graphs, descriptive statistics, and two sample tests for proportions (chi-square test) comparing different pairs of years. Results: Total Match participants increased in 2021 followed by a drop in 2022, and …
Associations Of Time To The Operating Room On Outcomes In Odontogenic Infection, Jeffrey N. James, Ryan Bloomquist, Kiara Brown, Stephen Looney, Dylan Walker, Tyler Day
Associations Of Time To The Operating Room On Outcomes In Odontogenic Infection, Jeffrey N. James, Ryan Bloomquist, Kiara Brown, Stephen Looney, Dylan Walker, Tyler Day
School of Dentistry Faculty Publications
The purpose of this study was to determine if there were correlations between the length of time from hospital admission to surgical intervention and the frequency of complications in patients with odontogenic infections. While odontogenic infection is well studied in terms of interventions and outcomes, less is known about hospital utilization and resource burden of odontogenic infection with respect to timeliness to intervention. A retrospective cohort analysis was used to examine correlations between time from admission to surgical intervention and clinical outcomes. Patients included in this study were divided into three categories of length of time to the operating room: …
Retreatability Of Endosequence® Bcs™ Hiflow Utilizing Both Chloroform And An Aqueous Solution, Dijana Elmejdoubi, Thomas E. Lallier, Masyn Cameron, Albert F. Mcmullen Iii
Retreatability Of Endosequence® Bcs™ Hiflow Utilizing Both Chloroform And An Aqueous Solution, Dijana Elmejdoubi, Thomas E. Lallier, Masyn Cameron, Albert F. Mcmullen Iii
School of Dentistry Faculty Publications
Purpose: When RCT fails, retreatment of the case usually requires removal of the previous root canal fill (RCF). The aim of our research was to evaluate the retreatability of a root canal initially filled with gutta percha and EndoSequence® BCS™ HiFlow utilizing chloroform followed by 18% HCl, 18% HCl alone, chloroform alone or saline solution. Methods: 40 extracted single canal teeth were decoronated and obturated utilizing a single cone gutta percha technique and Endosequence BCS, stored one week in an incubator, and then we attempted to remove the previous RCF. Teeth were divided in 4 different groups (n=10). Canals were …
Dental Clinic Deserts In The Us: Spatial Accessibility Analysis, Md Shahinoor Rahman, Jeffrey C. Blossom, Ichiro Kawachi, Renuka Tipirneni, Hawazin W. Elani
Dental Clinic Deserts In The Us: Spatial Accessibility Analysis, Md Shahinoor Rahman, Jeffrey C. Blossom, Ichiro Kawachi, Renuka Tipirneni, Hawazin W. Elani
School of Public Health Faculty Publications
IMPORTANCE: Little is known about the spatial accessibility to dental clinics across the US. OBJECTIVE: To map the spatial accessibility of dental clinics nationally and to examine the characteristics of counties and US Census block groups with dental care shortage areas. DESIGN, SETTING, AND PARTICIPANTS: Cross-sectional study of US dental clinics in 2023 using data from the IQVIA national practitioners' database, which includes 205 762 active dentists. Data were analyzed from November 2023 to April 2024. EXPOSURES: Socioeconomic characteristics of block groups and counties including rurality, area deprivation, racial and ethnic segregation, and uninsured population. MAIN OUTCOMES AND MEASURES: Enhanced …
Multiple Factors Regulate The Expression Of Sufcdsub In Streptococcus Mutans, Kassapa Ellepola, Lauren C. Guillot, Bradley Comeaux, Yiran Han, Jessica K. Kajfasz, Jacob P. Bitoun, Grace Spatafora, Jose A. Lemos, Zezhang T. Wen
Multiple Factors Regulate The Expression Of Sufcdsub In Streptococcus Mutans, Kassapa Ellepola, Lauren C. Guillot, Bradley Comeaux, Yiran Han, Jessica K. Kajfasz, Jacob P. Bitoun, Grace Spatafora, Jose A. Lemos, Zezhang T. Wen
School of Dentistry Faculty Publications
Introduction: The sufCDSUB gene cluster, encoding the sole iron-sulfur (Fe-S) cluster assembly system in S. mutans, was recently shown to be up-regulated in response to oxidative stressors and Fe limitation. Methods: In this study, luciferase reporter fusion assays, electrophoretic gel mobility shift assays (EMSA) and in vitro transcription assays (IVT) were used to dissect the cis- and trans-acting factors that regulate the expression of sufCDSUB. Results and discussion: Results showed deletion of perR, for the only Fur-family transcriptional regulator in S. mutans, resulted in > 5-fold increases in luciferase activity under the control of the sufCDSUB promoter (P < 0.01), as compared to the parent strain, UA159 when the reporter strains were grown in medium with no supplemental iron. Site-directed mutagenesis of a PerR-box in the promoter region led to elevation of the reporter activity by >1.6-fold (P < 0.01). In an EMSA, recombinant PerR (rPerR) was shown to bind to the cognate sufCDSUB promoter leading to mobility retardation. On the other hand, the reporter activity was increased by > 84-fold …
Periodontal Health In A Large Cohort Of Ugandans Living With Hiv: A Cross-Sectional Study, William Buwembo, Adriane Kamulegeya, Dunstan Kalanzi, Priscilla Naava Namuyonga, Proscovia Nakasujja, David P. Katete, F. Collins Semitala, Catherine Mwesigwa-Lutalo, Samuel Kalungi, Jennifer E. Cameron, Ian G. Munabi
Periodontal Health In A Large Cohort Of Ugandans Living With Hiv: A Cross-Sectional Study, William Buwembo, Adriane Kamulegeya, Dunstan Kalanzi, Priscilla Naava Namuyonga, Proscovia Nakasujja, David P. Katete, F. Collins Semitala, Catherine Mwesigwa-Lutalo, Samuel Kalungi, Jennifer E. Cameron, Ian G. Munabi
School of Medicine Faculty Publications
Background: The impact of periodontitis on large populations of people living with HIV (PLHIV) in resource-constrained settings remains largely un-investigated. This study aims to address this knowledge gap by providing a comprehensive description of the periodontal health status among a sizable cohort of Ugandans living with HIV. Methods: This was a cross-sectional study with 4,449 participants who were over 18-years old with data captured on their reported age, gender, tobacco use, length of time on HAART and alcohol use. Periodontal health was assessed using the WHO periodontal probe and the modified CPI data entry form. Descriptive statistics were reported using …
Effect Of Build Orientation On The Fabrication Trueness Of Additively Manufactured Implant-Supported Complete Arch Interim Fixed Prostheses, Amir H. Nejat, Mehmet Esad Güven, Gülce Çakmak, Burak Yilmaz, Mustafa Borga Donmez
Effect Of Build Orientation On The Fabrication Trueness Of Additively Manufactured Implant-Supported Complete Arch Interim Fixed Prostheses, Amir H. Nejat, Mehmet Esad Güven, Gülce Çakmak, Burak Yilmaz, Mustafa Borga Donmez
School of Dentistry Faculty Publications
PURPOSE: To evaluate how build orientation affects the fabrication trueness of additively manufactured implant-supported complete arch prostheses by comparing them to subtractively manufactured high-impact polymer-based prostheses. MATERIALS AND METHODS: An edentulous maxillary model with four implants at canine and first molar regions bilaterally was digitized (ATOS Core 80 5MP) to design a reference implant-supported complete arch prosthesis standard tessellation language file (RF-STL). The STL file was used to manufacture prostheses additively in five different orientations according to the build platform (AM-0, 0-degree; AM-15, 15-degree; AM-30, 30-degree; AM-45, 45-degree; AM-90, 90-degree) or subtractively (SM-HIP, control) (n = 10). The prostheses were …
A Novel Model Of Autologous Tooth Transplantation For The Study Of Nerve Recruitment, Teresa E. Fowler, Doan T. Bloomquist, Caroline Glessner, Poonam Patel, Jeffrey N. James, Kathryn Bollinger, Lynnette P. Mccluskey, Ryan F. Bloomquist
A Novel Model Of Autologous Tooth Transplantation For The Study Of Nerve Recruitment, Teresa E. Fowler, Doan T. Bloomquist, Caroline Glessner, Poonam Patel, Jeffrey N. James, Kathryn Bollinger, Lynnette P. Mccluskey, Ryan F. Bloomquist
School of Dentistry Faculty Publications
Background: Limited treatment options exist for damaged nerves and despite impressive advances in tissue engineering, scientists and clinicians have yet to fully replicate nerve development and recruitment. Innervation is a critical feature for normal organ function. While most organs are innervated prior to birth, a rare example of postnatal nerve recruitment occurs in the natural development of secondary teeth during adolescence. Many animals undergo postnatal shedding of deciduous teeth with development and eruption of secondary teeth, a process requiring recruitment of nerve and vasculature to each tooth pulp for viability. Here, the investigators created a novel model for the study …
Quantifying Radiographs In Endodontics: A Survey, Pavneet K. Bains, Albert F. Mcmullen Iii, Haley D. Kessler, Andrew G. Chapple
Quantifying Radiographs In Endodontics: A Survey, Pavneet K. Bains, Albert F. Mcmullen Iii, Haley D. Kessler, Andrew G. Chapple
School of Dentistry Faculty Publications
Purpose: The aim of this study was to investigate the average quantity of radiographs obtained during non-surgical endodontic treatment and trends in endodontic radiography among U.S. members of the AAE. Materials & Methods: A survey was sent via e-mail to 4,269 active U.S. members of the AAE. Data were collected over a period of approximately 4 months. The number of radiographs reported for non-surgical endodontic treatment was compared across fourteen variables using Kruskal Wallace tests. Chi Square tests of Independence were also used to evaluate trends in endodontic radiography based on three primary categorical variables of interest: years of experience, …
Endodontic Microsurgery Using Dynamic Navigation And Trephine Burs, Trenton Smith, Sameer Jain, Jeffery Nick Sanders, Michael Block, Mark Odom, Albert F. Mcmullen
Endodontic Microsurgery Using Dynamic Navigation And Trephine Burs, Trenton Smith, Sameer Jain, Jeffery Nick Sanders, Michael Block, Mark Odom, Albert F. Mcmullen
School of Dentistry Faculty Publications
Objectives: The use of the surgical operating microscope, CBCT imagining, biocompatible filling materials and ultrasonic instruments have improved the success and predictability of apical surgery. Despite these advances, more accurate and precise techniques for creating osteotomies and root-resections (apicoectomies) have not been widely adopted. This study highlights how dynamic navigation systems (DNS) can help avoid unnecessary dentin removal and “mitigate iatrogenic errors” such as root perforation. Methods: A total of 56 root-end resections were planned and completed on two sets of identical TrueJaw Endosurg models (DE Labs, Santa Barbra, CA, USA). One set of maxillary and mandibular jaws were used …
Addendum: A Small Molecule Produced By Lactobacillus Species Blocks Candida Albicans Filamentation By Inhibiting A Dyrk1-Family Kinase, Jessie Macalpine, Martin Daniel-Ivad, Zhongle Liu, Junko Yano, Nicole M. Revie, Robert T. Todd, Peter J. Stogios, Hiram Sanchez, Teresa R. O'Meara, Thomas A. Tompkins, Alexei Savchenko, Anna Selmecki, Amanda O. Veri, David R. Andes, Paul L. Fidel, Nicole Robbins, Justin Nodwell, Luke Whitesell, Leah E. Cowen
Addendum: A Small Molecule Produced By Lactobacillus Species Blocks Candida Albicans Filamentation By Inhibiting A Dyrk1-Family Kinase, Jessie Macalpine, Martin Daniel-Ivad, Zhongle Liu, Junko Yano, Nicole M. Revie, Robert T. Todd, Peter J. Stogios, Hiram Sanchez, Teresa R. O'Meara, Thomas A. Tompkins, Alexei Savchenko, Anna Selmecki, Amanda O. Veri, David R. Andes, Paul L. Fidel, Nicole Robbins, Justin Nodwell, Luke Whitesell, Leah E. Cowen
School of Dentistry Faculty Publications
No abstract provided.
Stratasys Printed 3-D Mandibular Molar With Tooth Anatomy And Texture, M. Austin White, Charles E. Taylor, Edwin Kee, Albert F. Mcmullen
Stratasys Printed 3-D Mandibular Molar With Tooth Anatomy And Texture, M. Austin White, Charles E. Taylor, Edwin Kee, Albert F. Mcmullen
School of Dentistry Faculty Publications
Introduction: We used CBCT scans of a human mandibular molar in concert with the Stratasys 3-D printer to fabricate said teeth with similar texture and hardness to enamel, dentin, and cementum. The printed tooth should also have the same crown and root anatomy, as well as root canal anatomy of the scanned tooth. Methods: One mandibular first molar was scanned (Carestream Dental CS 9600 CBCT) and printed (Stratasys 3D multi-material printer). A (Micromet 5104) hardness tester was used to test the hardness of the printed tooth. Nine combinations of two different materials (Stratasys’ Vero Pure White and Agilus 30 Clear …
A Fungal Metabolic Regulator Underlies Infectious Synergism During Candida Albicans-Staphylococcus Aureus Intra-Abdominal Co-Infection, Saikat Paul, Olivia A. Todd, Kara R. Eichelberger, Christine Tkaczyk, Bret R. Sellman, Mairi C. Noverr, James E. Cassat, Paul L. Fidel, Brian M. Peters
A Fungal Metabolic Regulator Underlies Infectious Synergism During Candida Albicans-Staphylococcus Aureus Intra-Abdominal Co-Infection, Saikat Paul, Olivia A. Todd, Kara R. Eichelberger, Christine Tkaczyk, Bret R. Sellman, Mairi C. Noverr, James E. Cassat, Paul L. Fidel, Brian M. Peters
School of Dentistry Faculty Publications
Candida albicans and Staphylococcus aureus are two commonly associated pathogens that cause nosocomial infections with high morbidity and mortality. Our prior and current work using a murine model of polymicrobial intra-abdominal infection (IAI) demonstrates that synergistic lethality is driven by Candida-induced upregulation of functional S. aureus α-toxin leading to polymicrobial sepsis and organ damage. In order to determine the candidal effector(s) mediating enhanced virulence, an unbiased screen of C. albicans transcription factor mutants was undertaken revealing that zcf13Δ/Δ fails to drive augmented α-toxin or lethal synergism during co-infection. A combination of transcriptional and phenotypic profiling approaches shows that ZCF13 regulates …