Dentistry Commons^™

Comparison Of Centering Ability And Fatigue Resistance Of Three Nickel-Titanium Rotary Instruments: An In-Vitro Study, Yousra A. S. Moustafa, Medhat T. El Faramawy, Tariq Y. Abdelrahman

Mansoura Journal of Dentistry

Objective

To evaluate canal centering ability by using different irrigants and cyclic fatigue resistance.

Materials and methods

Sixty-three teeth were randomly classified into three main groups according to the type of files: group 1 (n=21) M-Pro Files. Group 2 (n=21) 2Shape files. Group 3 (n=21) ProTaper Universal files (PTU). Each group was subdivided into 3 subgroups according to the type of irrigation used (Saline, NaOCl, MTAD). A total of 42 rotary files (M-pro, 2Shape, PTU) were classified into 3 main groups. Each group (n=14), then each group was subdivided into 2 subgroups (n=7). Data were analyzed using Shapiro-Wilk test. Data …

Evaluation The Adhesive Remnant Index Of Two Different Adhesive Systems Using Two Different Curing Times, Mohammad Riad Al Salem, Nehal Fouad Albelasy, Essam Elsaeid Al-Wakeel, Yasser Lotfy Abdelnaby

Mansoura Journal of Dentistry

Objectives: To evaluate the adhesive remnant index (ARI) of orthodontic brackets bonded with two adhesive systems using two different light curing times.

Materials and methods: Fifty-six extracted premolars were divided into two groups (n= 28) depending on the type of adhesive system used; Total-Etch (TE) Transbond XT and Self-Etch (SE) Transbond Plus. Each group was subdivided into two subgroups (n= 14) based on the curing time; 20 seconds and 3 seconds. The ARI was evaluated in each subgroup. The significance level was set at P≤ 0.050.

Results: The ARI showed that there was a statistically significant difference in ARI between …

Two Different Treatment Options For Cad\Cam Constructed Mandibular Class I Rpds. Clinical And Radiographic Evaluation Of Abutment Teeth Tissue Health., Nermeen Elsayed El-Khamisy, Aisha Zakaria Hashem Mostafa

Mansoura Journal of Dentistry

Objective: This study was conducted to assess the abutment teeth for digitally constructed clasp-retained and attachment-retained removable partial dentures (RPD) in cases with a class I partially edentulous mandible. Material and methods: In this clinical trial, throughout six years, 10 patients each received two mandibular class I RPDs that were created using computer-aided design and computer-aided manufacturing (CAD-CAM) over six years. The first one was clasp retained RPD (Group1) for 3 years then extra-coronal attachment with cantilever retained RPD for an additional 3 years (Group 2). The abutment's clinical parameters (pocket depth, bleeding index, and plaque index) and alveolar bone …

Universal Versus Glass Ionomer –Based Adhesive: Effect On Shear Bond Strength And Micro-Morphological Analysis Of Resin Modified Glass Ionomer Restorative Material /Dentin Interface, Gehad Mohamed Kassem, Huda Abed El -Haliem Mohammed, Ashraf Ibrahim Ali

Mansoura Journal of Dentistry

Objectives: : To evaluate universal versus glass ionomer –based adhesive, effect on shear bond strength and micro-morphological analysis of resin modified glass ionomer restorative material /dentin interface.

Materials and methods: 120 sound human molars were selected for our study. Subsequently, teeth were prepared by removing the occlusal enamel and exposing mid dentin. The roots of teeth were fixed to the base of a tube filled with acrylic resin. Teeth were divided into two groups according to type of RMGI (n=60) and then each group was subdivided into three subgroups according to adhesive use (n=20). Cylindrical tubes were built by the …

Evaluation Of Pain After Third Molar Extraction Surgery Using Hyaluronic Acid Versus Ozone Gel As Socket Preservatives, Heba Yahya Kandeel, Mohammed Abdel-Monem Tawfik, Farid Abd-Elreheim Badria, Eman Abdelsalam Yossef

Mansoura Journal of Dentistry

Objectives: This study aimed to evaluate pain following surgical extraction of the impacted mandibular third molar with inward fragmentation technique in combination with the use of ozone gel versus hyaluronic acid for socket preservation.

Patients and methods: This study involved 45 patients who were randomly divided into three equal groups after extraction of their impacted mandibular third molars, as follows: group I: ozone gel was placed in the socket, group II: hyaluronic acid gel was placed in the socket, while in group III (control group): normal healing was allowed without placing any material in the socket. All patients were assessed …

Application Of Mcnamara Analysis To Evaluate The Skeletal And Dentoalveolar Effects Of The Hybrid Aesthetic Functional Appliance On Class Ii Division 1 Malocclusion, Sohaila Adnan Ahmed Zehairy, Mohammad Hasan Abdellatief, Ahmed Maher Fouda

Mansoura Journal of Dentistry

Objective: This study aimed to assess the skeletal and dento-alveolar changes associated with using the new hybrid aesthetic functional appliance in the correction of class II division 1 malocclusion. Materials and Methods: Sixteen patients aged (8-12y) who had skeletal class II division 1 caused by mandibular deficiency were chosen and treated with the hybrid aesthetic function appliance. Before and after treatment, lateral cephalometric radiographs, photographs and study casts were taken. The duration of treatment was about 9-12 months. Results: The hybrid aesthetic functional appliance improved the mandibular forward position (P = 0.005) and increased the mandibular effective length (P = …

Effect Of Different Caries Removal Methods On Microtensile Bond Strength Of Universal Adhesive-Affected Dentin Interface, Amira Yahia Ghonim, Huda Abed El-Haliem, Mohamed Samir Elnawawy, Ashraf Ibrahim Ali

Mansoura Journal of Dentistry

Abstract

Objectives: To investigate the effect of three caries removal methods; air abrasion, papain gel, carbide bur, and water storage on microtensile bond strength of universal adhesives to affected dentin.

Materials and methods: Two universal adhesives; glycero-phosphate dimethacrylate (GPDM) containing OptiBond universal (Kerr Medical, USA) and 10-Methacryloyloxydecyl dihydrogen phosphate (10-MDP) containing Prime&Bond universal (Dentsply Sirona, USA) were used in this study according to their manufacturers' instructions. Forty-eight carious human molars were mounted into acrylic blocks then the coronal enamel and dentin were removed exposing a flat surface of affected dentin. Teeth were divided into two groups (n=24) according to the …

Evaluation Of Extrusion Arch In Management Of Anterior Open Bite In Mixed Dentition Patients, Mai Ebrahem Abdelmonem, Nehal Fouad Albelasy, Yasser Lotfy Abdelnaby, Maher Abd El Salam Fouda

Mansoura Journal of Dentistry

Objectives: To evaluate the dentoalveolar and skeletal changes of anterior open bite (AOB) treatment using extrusion arch in the mixed dentition.

Materials and methods: The study included 12 patients (7 females and 5 males) in the mixed dentition stage with an age range from 8 to 11 years with dentoalveolar anterior open bite ≤ 0 mm with normal facial pattern SN-GoGn (31.54°) and insufficient incisor display. After leveling & alignment for the upper incisors, a sectional heavy wire of 0.017 x 0.025'' stainless steel was kept in the upper incisors' brackets. The extrusion arch was placed as an auxiliary arch …

Bond Strength Of Zirconia Ceramics To Dentin Using Two Resin Cements: Influence Of Dentin Conditioning, Ahmed Mohamed Abd El-Khbeer, Ahmed Attia Abo El-Naga, Sayed Mohamed Ghorab

Mansoura Journal of Dentistry

Objective: To assess the impact of different dentin conditioning methods and two resin cements on the bond strength of zirconia ceramics to dentin.

Materials and Methods: A total of 64 zirconia discs fabricated using CAD/CAM technology of dimensions (8mm diameter ×3mm thickness) and 64 molars mounted in plastic rings with acrylic resin were prepared by exposing flat coronal dentin surfaces. They were divided into 4 main groups (n=16) according to dentin surface treatment; Dentin as cut, treated with EDTA, Polyacrylic Acid (PAA), and self-etch adhesive. Each main group was subdivided into 2 subgroups (n=8) according to the luting cement used: …

Clasp Retained Versus Attachment Retained Removable Partial Dentures For Treatment Of Mandibular Distal Extension Cases: Patient Satisfaction And Oral Health-Related Quality Of Life, Nermeen Elsayed Khalil El-Khamisy

Mansoura Journal of Dentistry

Objective: This study was carried out to assess patient satisfaction by visual analogue scale (VAS) and oral health-related quality of life (OHRQL) for digitally constructed clasp-retained and attachment-retained removable partial dentures (ARRPDs) in a mandibular class I partially edentulous cases Materials and methods: In this clinical trial,18 patients were equally divided into 2groups, they received mandibular class I computer-aided design/computer-aided manufacturing (CAD/CAM) constructed RPDs, patients were received RPDs retained with RPA clasp system (Group 1) for 6 months and the other patients were received RPDs retained with extra-coronal attachment (ARRPDs)) with cantilever for 6 months (Group 2). After receiving and …

Large-Scale Exome Array Summary Statistics Resources For Glycemic Traits To Aid Effector Gene Prioritization, Sara M Willems, Natasha H J Ng, Juan Fernandez, Rebecca S Fine, Eleanor Wheeler, Jennifer Wessel, Hidetoshi Kitajima, Gaelle Marenne, Xueling Sim, Hanieh Yaghootkar, Shuai Wang, Sai Chen, Yuning Chen, Yii-Der Ida Chen, Niels Grarup, Ruifang Li-Gao, Tibor V Varga, Jennifer L Asimit, Shuang Feng, Rona J Strawbridge, Erica L Kleinbrink, Tarunveer S Ahluwalia, Ping An, Emil V Appel, Dan E Arking, Juha Auvinen, Lawrence F Bielak, Nathan A Bihlmeyer, Jette Bork-Jensen, Jennifer A Brody, Archie Campbell, Audrey Y Chu, Gail Davies, Ayse Demirkan, James S Floyd, Franco Giulianini, Xiuqing Guo, Stefan Gustafsson, Anne U Jackson, Johanna Jakobsdottir, Marjo-Riitta Järvelin, Richard A Jensen, Stavroula Kanoni, Sirkka Keinanen-Kiukaanniemi, Man Li, Yingchang Lu, Jian'an Luan, Alisa K Manning, Jonathan Marten, Karina Meidtner, Dennis O Mook-Kanamori, Taulant Muka, Giorgio Pistis, Bram Prins, Kenneth M Rice, Serena Sanna, Albert Vernon Smith, Jennifer A Smith, Lorraine Southam, Heather M Stringham, Vinicius Tragante, Sander W Van Der Laan, Helen R Warren, Jie Yao, Andrianos M Yiorkas, Weihua Zhang, Wei Zhao, Mariaelisa Graff, Heather M Highland, Anne E Justice, Eirini Marouli, Carolina Medina-Gomez, Saima Afaq, Wesam A Alhejily, Najaf Amin, Folkert W Asselbergs, Lori L Bonnycastle, Michiel L Bots, Ivan Brandslund, Ji Chen, John Danesh, Renée De Mutsert, Abbas Dehghan, Tapani Ebeling, Paul Elliott, Epic-Interact Consortium, Aliki-Eleni Farmaki, Jessica D Faul, Paul W Franks, Steve Franks, Andreas Fritsche, Anette P Gjesing, Mark O Goodarzi, Vilmundur Gudnason, Göran Hallmans, Tamara B Harris, Karl-Heinz Herzig, Marie-France Hivert, Torben Jørgensen, Marit E Jørgensen, Pekka Jousilahti, Eero Kajantie, Maria Karaleftheri, Sharon L R Kardia, Leena Kinnunen, Heikki A Koistinen, Pirjo Komulainen, Peter Kovacs, Johanna Kuusisto, Markku Laakso, Leslie A Lange, Lenore J Launer, Aaron Leong, Jaana Lindström, Jocelyn E Manning Fox, Satu Männistö, Nisa M Maruthur, Leena Moilanen, Antonella Mulas, Mike A Nalls, Matthew Neville, James S Pankow, Alison Pattie, Eva R B Petersen, Hannu Puolijoki, Asif Rasheed, Paul Redmond, Frida Renström, Michael Roden, Danish Saleheen, Juha Saltevo, Kai Savonen, Sylvain Sebert, Tea Skaaby, Kerrin S Small, Alena Stančáková, Jakob Stokholm, Konstantin Strauch, E-Shyong Tai, Kent D Taylor, Betina H Thuesen, Anke Tönjes, Emmanouil Tsafantakis, Tiinamaija Tuomi, Jaakko Tuomilehto, Understanding Society Scientific Group;, Matti Uusitupa, Marja Vääräsmäki, Ilonca Vaartjes, Magdalena Zoledziewska, Goncalo Abecasis, Beverley Balkau, Hans Bisgaard, Alexandra I Blakemore, Matthias Blüher, Heiner Boeing, Eric Boerwinkle, Klaus Bønnelykke, Erwin P Bottinger, Mark J Caulfield, John C Chambers, Daniel I Chasman, Ching-Yu Cheng, Francis S Collins, Josef Coresh, Francesco Cucca, Gert J De Borst, Ian J Deary, George Dedoussis, Panos Deloukas, Hester M Den Ruijter, Josée Dupuis, Michele K Evans, Ele Ferrannini, Oscar H Franco, Harald Grallert, Torben Hansen, Andrew T Hattersley, Caroline Hayward, Joel N Hirschhorn, Arfan Ikram, Erik Ingelsson, Fredrik Karpe, Kay-Tee Kaw, Wieland Kiess, Jaspal S Kooner, Antje Körner, Timo Lakka, Claudia Langenberg, Lars Lind, Cecilia M Lindgren, Allan Linneberg, Leonard Lipovich, Ching-Ti Liu, Jun Liu, Yongmei Liu, Ruth J F Loos, Patrick E Macdonald, Karen L Mohlke, Andrew D Morris, Patricia B Munroe, Alison Murray, Sandosh Padmanabhan, Colin N A Palmer, Gerard Pasterkamp, Oluf Pedersen, Patricia A Peyser, Ozren Polasek, David Porteous, Michael A Province, Bruce M Psaty, Rainer Rauramaa, Paul M Ridker, Olov Rolandsson, Patrik Rorsman, Frits R Rosendaal, Igor Rudan, Veikko Salomaa, Matthias B Schulze, Robert Sladek, Blair H Smith, Timothy D Spector, John M Starr, Michael Stumvoll, Cornelia M Van Duijn, Mark Walker, Nick J Wareham, David R Weir, James G Wilson, Tien Yin Wong, Eleftheria Zeggini, Alan B Zonderman, Jerome I Rotter, Andrew P Morris, Michael Boehnke, Jose C Florez, Mark I Mccarthy, James B Meigs, Anubha Mahajan, Robert A Scott, Anna L Gloyn, Inês Barroso

Faculty, Staff and Student Publications

Background: Genome-wide association studies for glycemic traits have identified hundreds of loci associated with these biomarkers of glucose homeostasis. Despite this success, the challenge remains to link variant associations to genes, and underlying biological pathways.

Methods: To identify coding variant associations which may pinpoint effector genes at both novel and previously established genome-wide association loci, we performed meta-analyses of exome-array studies for four glycemic traits: glycated hemoglobin (HbA1c, up to 144,060 participants), fasting glucose (FG, up to 129,665 participants), fasting insulin (FI, up to 104,140) and 2hr glucose post-oral glucose challenge (2hGlu, up to 57,878). In addition, we performed network …

Identification Of Microbiological Factors Associated With Periodontal Health Disparities, Bing-Yan Wang, Aize Cao, Meng-Hsuan Ho, Derek Wilus, Sally Sheng, Hsiu-Wan Meng, Elissa Guerra, Jianming Hong, Hua Xie

Faculty, Staff and Student Publications

The present study aimed at identifying risk factors associated with periodontitis development and periodontal health disparities with emphasis on differential oral microbiota. The prevalence of periodontitis is recently rising dentate adults in the US, which presents a challenge to oral health and overall health. The risk of developing periodontitis is higher in African Americans (AAs), and Hispanic Americans (HAs) than in Caucasian Americans (CAs). To identify potentially microbiological determinations of periodontal health disparities, we examined the distribution of several potentially beneficial and pathogenic bacteria in the oral cavities of AA, CA, and HA study participants. Dental plaque samples from 340 …

Assessing The Most Vulnerable Subgroup To Type Ii Diabetes Associated With Statin Usage: Evidence From Electronic Health Record Data, Xinzhou Guo, Waverly Wei, Molei Liu, Tianxi Cai, Chong Wu, Jingshen Wang

Faculty, Staff and Student Publications

There have been increased concerns that the use of statins, one of the most commonly prescribed drugs for treating coronary artery disease, is potentially associated with the increased risk of new-onset Type II diabetes (T2D). Nevertheless, to date, there is no robust evidence supporting as to whether and what kind of populations are indeed vulnerable for developing T2D after taking statins. In this case study, leveraging the biobank and electronic health record data in the Partner Health System, we introduce a new data analysis pipeline and a novel statistical methodology that address existing limitations by (i) designing a rigorous causal …

Micro-Tensile Bond Strength Of Three Different Dual Cure Resin Composites Bonded To Dentin, Atya A. Alzarouq, Rabab Mehesen, Ashraf I. Ali

Mansoura Journal of Dentistry

Objective: To evaluate the micro-tensile bond strength (μTBS) and micro-morphological analysis of composite dentin interface of dual-cure resin composites bonded to dentin. Materials and Methods: For the micro-tensile bond strength test, sixty sound human maxillary and mandibular molars were collected. After embedding the selected molars in an acrylic resin block, the occlusal enamel and superficial dentin of each tooth were removed, exposing the mid-dentin area. They were assigned randomly into three groups (n=20) according to the restorative system. Then both groups were further divided into two subgroups; subgroup 1 for immediately tested specimens after 24 h (n=10), and subgroup 2 …

Evaluation Of Microtensile Bond Strength, Microleakage Pattern And Micromorphological Analysis Of New Functional Monomer-Based Universal Adhesive Tooth Interface, Hussain R. Khaled, Hamdi H. Hammama, Salah H. Mahmoud

Mansoura Journal of Dentistry

Objective: This study was intended to evaluate the micro tensile bond strength (μTBS), micro leakage pattern, and micro morphological analysis of new 10-MDP-based universal adhesive/tooth interface and compare it with other two 10-MDP-based adhesive systems before and after storage. Materials and Methods: Two Universal adhesives (Single Bond Universal Adhesive and Ambar Universal) and one all-in-one adhesive (CLEARFIL S3BOND) were used. A total of 102 permanent human molars were used in this study. The teeth were randomly divided into three groups (n=34) according to the type of used adhesive; Ambar Universal (AU), CLEARFIL S3BOND (CTS), and Single Bond Universal (SBU). Each …

Anti-Dysplastic Effect Of Nettle Extract And Its Nano-Formulation On 7,12-Dimethylbenz[A]Anthracene Induced Hamster Buccal Pouch Carcinogenesis, Samah K. Ezzat, Amira M. Elsherbini

Mansoura Journal of Dentistry

Objective: Oral squamous cell carcinoma (OSCC) is the most common malignancy in the oral cavity with no definitive cure. In this study, chitosan loaded with nettle was used for the treatment of 7,12-Dimethylbenz[a] anthracene (DMBA)-induced oral squamous cell carcinoma compared to regular chemotherapy with 5-Fluorouracil (5-FU).Material and methods: Sixty pathogen-free male Syrian golden hamsters were used. The control group served as a negative control with no intervention, while the remaining animals received DMBA for 16 weeks then they were divided equally into 5 groups as follows; DMBA group received no treatment, while the 5-FU group was treated with 15mg/kg of …

Immunohistochemical Assessment Of Angiogenesis And Cell Proliferation In Aggressive Versus Non-Aggressive Central Giant Cell Granuloma., Mena F. Mesiha, Mahmoud F. El Sherbeny, Sherif Y. El Nagdy

Mansoura Journal of Dentistry

Objective: The current study investigated the expression of MCM3 and CD31 in aggressive versus non-aggressive central giant cell granuloma (CGCG ) Materials and methods: Thirty-three paraffin blocks for CGCG cases were collected from Oral Pathology Departments, Faculty of Dentistry, Mansoura, and Alexandria Universities. The Immunohistochemical staining for CD31 and MCM 3 was performed, assessed, and scored. Results: Mean age of the studied cases was 35.6±9.1 years. The lesions that occurred in the mandible represented the majority of cases [27 cases (81.8%)]. The study revealed an association between aggressiveness and the presence of large swelling, pain, cortical perforation, root resorption, and …

Stem Cell Marker As A Factor For The Different Biological Behavior Of Ameloblastoma And Odontogenic Keratocyst, Hanan M. Sayed Ahmed, Doaa A. Esmaeil, Sherif Y. Elnagdy

Mansoura Journal of Dentistry

Objective: To investigate the immunohistochemical expression of SOX2 among the studied cases of ameloblastoma and odontogenic keratocyst in order to show if it correlates to the biological behavior of those odontogenic lesions. Materials and Methods: The study was carried out on 30 histo-pathologically confirmed cases of (15 ameloblastomas and 15 odontogenic keratocysts). These blocks were collected from archived files of the Department of Oral Pathology, Faculty of Dentistry, Mansoura University. Sections were subjected to Immunohistochemical staining by SOX2 according to a standard protocol. Results: OKCs showed higher expression of SOX2 than Ab in all epithelial layers not confined to the …

Clinicopathological Study Of Oral Plasma Cell Granuloma, Aya M. El-Bastawesi, Mona M. Ibrahim, Nadia A. El-Sissy

Mansoura Journal of Dentistry

Objective: To identify the characteristic clinical and Histopathologic features encountered in the oral lesions of PCG and thus, clarifying the variability nature of the studied oral plasma cell granulomas (OPCGS). Materials and Methods a sample of 25 retrospective paraffin blocks of the OPCGS were thoroughly investigated histopathologically. Results: the studied OPCG was mainly represented as a gingival swelling, there was a female tendency in most of the studied OPCGS (92%), ranging from 11-73 years with a mean of 42.40. the majority of the current OPCG (64%) did not express any bone changes. the OPCGS of the present work were characterized …

Immunohistochemical Expression Of Ezh2 In Mucoepidermoid Carcinoma Of Salivary Glands, Amira A. Mansour, Mona M. Ibrahim, Ahmed E. Ahmed, Azza A. El Sissi

Mansoura Journal of Dentistry

Objective: To disclose the variation in EZH2 expression among the different grades of MEC and to analyze the marker's immunohistochemical (IHC) expression in relation to the clinicopathologic data of all cases. Material and methods: The present study was conducted on 15 blocks diagnosed as MEC including equal numbers of different grades. These blocks were selected from the archives of the Oncology Center, Mansoura University. The specimens embedded in the retrieved paraffin blocks were all fixed in 10% formalin. Sections of 4 microns’ thickness intervals were serially cut and prepared for the EZH2 staining. Chi-square, Monte Carlo, and Fisher Exact tests …

Effect Of Food Simulating Solvents On Surface Roughness And Microhardness Of Bulk Fill Resin Composites., Hadeer M. Hal, Ashraf I. Ali, Noha A. El-Wassefy, Marmar A. Montaser

Mansoura Journal of Dentistry

Objectives: To evaluate the effect of food simulating solvents on surface roughness and microhardness of bulk fill resin composites in-vitro. Materials and methods: A total of 180 discs were made with (Filtek One bulk fill, REVEAL HD and x-tra fil bulk fill (n=60). The baseline data of surface roughness and microhardness measurements were recorded. Each group was divided into three subgroups, subgroup1 was immersed into methyl ethyl ketone (n=20), subgroup2 was immersed into ethanol (n=20) and, subgroup3 was immersed into artificial saliva (n=20) as control group. After 30 days, half of each subgroup was tested for surface roughness (n=10) by …

Mdpb-Containing Self-Etch Dental Adhesive: Antibacterial Activity And Effect Of Different Dentinal Surface Preparation, Sally N. Zaki, Ragy N. Saad, Hamdi H. Hamdan, Salah H. Mahmoud

Mansoura Journal of Dentistry

Objective: To evaluate the effect of MDBP-containing self-etch (SE) adhesive and different dentin surface pretreatments on antibacterial activity Materials and Methods: A total of forty disc shaped specimens fabricated (8 mm in diameter and 1.5 mm thickness) were divided into four main groups according to type of the surface treatment method; deionized water(control), CHX, Papin enzyme and Riboflavin. Each group was sub-divided into 2subgroups (n=5) according to the type of adhesive: classic or MDPB containing SE adhesives. Bonded specimens were stored in deionized water for 24 hr. (n=6). The plates contained dices shaped specimen was incubated at 37o C for …

Comparing Shaping Ability Of Fanta, Onecurve, And Protaper Next Ni-Ti Rotary Files Systems., Soliman N. Mansour, Maram Obeid, Tariq Yehia

Mansoura Journal of Dentistry

Objective: To compare the shaping ability of Fanta, One Curve, and Pro Taper Next Ni-Ti rotary file systems. Materials and Methods: Sixty Mandibular molars with mesiobuccal canals with curvatures ranging between 20° and 40° were divided into three groups of 20 teeth each. a group for each system as follows: group 1 was prepared by Fanta file system, group 2 was prepared by Pro Taper Next file system, and group 3 was prepared by One Curve file system. The measuring of canal curvatures was determined by Schneider's method using standardized periapical radiographs and the Image J software. Pre and post-CBCT …

Comparative Study Of Protrusive Record Accuracy With And Without George Gauge For Dentulous Cases, Aisha Z. Mostafa, Noha H. El-Shaheed

Mansoura Journal of Dentistry

Objective: This study aimed to evaluate the accuracy of the George gauge in protrusive records. Materials and Methods: This clinical trial includes a total of 12 dentulous subjects aged 20 to 40 years with no signs of muscular disease or temporomandibular joint disorders were chosen. For each patient, two different protrusive records were created, one with and one without the George gauge, using polyvinyl siloxane materials. The accuracy of these two protrusive records was evaluated by measuring the amount of midline shift in both records with a digital calliper. Then these Protrusive records were used to programme the articulator and …

Soft Metal Versus Laser Melting Metal Framework Used For Mandibular All On Four Implant Supported Fixed Complete Denture, Noha H. Rashed, Noha H. El Shaheed, Wael M. Said Ahmed, Salah A. Hegazy

Mansoura Journal of Dentistry

Objective: To radiographically evaluate the peri-implant bone height changes eri-implantin mandibular all on-four implant supported fixed complete denture (ISFCD) regarding metal framework fabrication technique either with milling from soft metal block or additive manufacturing using laser melting. Materials and Methods: Ten completely edentulous patients were rehabilitated with mandibular all on-four ISFCD. Computer-guided surgical procedures were followed for placement of implants. Patients were allocated randomly into two groups according to the framework fabrication technique. Group I frameworks were milled from soft metal block and group II frameworks were fabricated with additive manufacturing using laser melting. Vertical bone height changes around supporting …

Clinical And Patient-Reported Outcomes After Recession Coverage Using Modified Vestibular Incision Subperiosteal Tunnel Access With A Volume-Stable Collagen Matrix As Compared To A Coronally Advanced Flap With A Subepithelial Connective Tissue Graft, Chun-Teh Lee, Marlena Lange, Alain Jureidini, Nurit Bittner, Ulrike Schulze-Späte

Faculty, Staff and Student Publications

Purpose: Coronally advanced split-or full-thickness (CAST or CAFT) flaps in combination with subepithelial connective tissue grafts (SCTGs) are commonly used in root-coverage procedures despite postoperative pain and bleeding from the graft donor site. Therefore, the modified vestibular incision subperiosteal tunnel access procedure (VISTAX) uses a novel collagen matrix (VCMX) instead of autogenous tissue to address the limitations associated with autogenous tissue grafting. This retrospective study compared the clinical outcomes of VISTAX to the results obtained after using a CAST or CAFT flap in combination with SCTG for root coverage.

Methods: Patients with single or multiple adjacent recession I/II defects were …

Massive Macroglossia, A Rare Side Effect Of Covid-19: Clinical, Histologic, And Genomic Findings In Covid-19-Positive Versus Covid-19-Negative Patients, Victoria A Mañón, David Chubb, Laura S Farach, Rachid Karam, Mary C Farach-Carson, Nadarajah Vigneswaran, Karan Saluja, Simon Young, Mark Wong, James C Melville

Faculty, Staff and Student Publications

PURPOSE: The primary purpose of this study is to identify if there is an underlying genetic predisposition for COVID-related macroglossia and if this susceptibility is higher among individuals of African heritage. Secondary objectives include determining if genetic testing of COVID-infected patients who are intubated and prone could identify patients with higher susceptibility to the development of macroglossia.

METHODS: A retrospective chart review was completed for each patient, and prospectively, genetic and histopathologic analyses were completed. Whole-exome sequencing was completed on two patients; immunohistochemistry was completed on the COVID-positive tissue samples.

RESULTS: Histopathology of the COVID-positive patient revealed significant peri-lymphocytic infiltrate, …

The Fate Of Early Perichondrial Cells In Developing Bones, Yuki Matsushita, Angel Ka Yan Chu, Chiaki Tsutsumi-Arai, Shion Orikasa, Mizuki Nagata, Sunny Y Wong, Joshua D Welch, Wanida Ono, Noriaki Ono

Faculty, Staff and Student Publications

In endochondral bone development, bone-forming osteoblasts and bone marrow stromal cells have dual origins in the fetal cartilage and its surrounding perichondrium. However, how early perichondrial cells distinctively contribute to developing bones remain unidentified. Here we show using in vivo cell-lineage analyses that Dlx5+ fetal perichondrial cells marked by Dlx5-creER do not generate cartilage but sustainably contribute to cortical bone and marrow stromal compartments in a manner complementary to fetal chondrocyte derivatives under the regulation of Hedgehog signaling. Postnatally, Dlx5+ fetal perichondrial cell derivatives preferentially populate the diaphyseal marrow stroma with a dormant adipocyte-biased state and are refractory to parathyroid …

Effect Of Selective Decontamination Of The Digestive Tract On Hospital Mortality In Critically Ill Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial, The Suddicu Investigators For The Australian And New Zealand Intensive Care Society Clinical Trials Group, John A Myburgh, Ian M Seppelt, Fiona Goodman, Laurent Billot, Maryam Correa, Joshua S Davis, Anthony C Gordon, Naomi E Hammond, Jon Iredell, Qiang Li, Sharon Micallef, Jennene Miller, Jayanthi Mysore, Colman Taylor, Paul J Young, Brian H Cuthbertson, Simon R Finfer

Faculty, Staff and Student Publications

IMPORTANCE: Whether selective decontamination of the digestive tract (SDD) reduces mortality in critically ill patients remains uncertain.

OBJECTIVE: To determine whether SDD reduces in-hospital mortality in critically ill adults.

DESIGN, SETTING, AND PARTICIPANTS: A cluster, crossover, randomized clinical trial that recruited 5982 mechanically ventilated adults from 19 intensive care units (ICUs) in Australia between April 2018 and May 2021 (final follow-up, August 2021). A contemporaneous ecological assessment recruited 8599 patients from participating ICUs between May 2017 and August 2021.

INTERVENTIONS: ICUs were randomly assigned to adopt or not adopt a SDD strategy for 2 alternating 12-month periods, separated by a …

Dental Fear, Anxiety, And Phobia; Causes, Diagnostic Criteria And The Medical And Social Impact, Nadya Avramova

Journal of Mind and Medical Sciences

Despite technological advances in modern medical science and practice, many people still associate dental treatment with unpleasant emotional sensations and pain. According to the current literature, dental fear and anxiety are psychological barriers that negatively affect frequency of patient attendance which results in avoidant behavior and poorer oral health-related quality of life.

This paper was therefore aimed at discussing basic theoretical aspects concerning diagnostic criteria, causes, and impacts of dental fear, anxiety, and phobia. Clarifying their differential diagnostic characteristics, clinical features and specific causes may play an important role in proper diagnosing, positive influencing, and management of this group of …