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Articles 121 - 150 of 406

Full-Text Articles in Dentistry

Oral Microbiome Associated With Differential Ratios Of Porphyromonas Gingivalis And Streptococcus Cristatus, Qingguo Wang, Bing-Yan Wang, Siddharth Pratap, Hua Xie Feb 2024

Oral Microbiome Associated With Differential Ratios Of Porphyromonas Gingivalis And Streptococcus Cristatus, Qingguo Wang, Bing-Yan Wang, Siddharth Pratap, Hua Xie

Faculty, Staff and Student Publications

Periodontitis has recently been defined as a dysbiotic disease caused by an imbalanced oral microbiota. The transition from commensal microbial communities to periodontitis-associated ones requires colonization by specific pathogens, including Porphyromonas gingivalis. We previously reported an antagonistic relationship between Streptococcus cristatus and P. gingivalis. To determine the role of S. cristatus in altering the interactions of P. gingivalis with other oral bacteria in a complex context, we collected dental plaque samples from patients with periodontitis and assigned them to two groups based on the ratios of S. cristatus and P. gingivalis. We then characterized the microbial profiles …


Sionx Coating Regulates Mesenchymal Stem Cell Antioxidant Capacity Via Nuclear Erythroid Factor 2 Activity Under Toxic Oxidative Stress Conditions, Neelam Ahuja, Kamal Awad, Su Yang, He Dong, Antonios Mikos, Pranesh Aswath, Simon Young, Marco Brotto, Venu Varanasi Feb 2024

Sionx Coating Regulates Mesenchymal Stem Cell Antioxidant Capacity Via Nuclear Erythroid Factor 2 Activity Under Toxic Oxidative Stress Conditions, Neelam Ahuja, Kamal Awad, Su Yang, He Dong, Antonios Mikos, Pranesh Aswath, Simon Young, Marco Brotto, Venu Varanasi

Faculty, Staff and Student Publications

Healing in compromised and complicated bone defects is often prolonged and delayed due to the lack of bioactivity of the fixation device, secondary infections, and associated oxidative stress. Here, we propose amorphous silicon oxynitride (SiONx) as a coating for the fixation devices to improve both bioactivity and bacteriostatic activity and reduce oxidative stress. We aimed to study the effect of increasing the N/O ratio in the SiONx to fine-tune the cellular activity and the antioxidant effect via the NRF2 pathway under oxidative stress conditions. The in vitro studies involved using human mesenchymal stem cells (MSCs) to examine the effect of …


Evaluation Of The Effectiveness Of Telemedicine In Postoperative Follow-Up Care After Dental Implant Surgery A Pilot Study, Praveen Kumar Patel, Anuj Kishor Shukla, Varun Sachan, Paawan Sharma, Sonal Singh, Swapnil Saxena, Ramanpal S Makkad Feb 2024

Evaluation Of The Effectiveness Of Telemedicine In Postoperative Follow-Up Care After Dental Implant Surgery A Pilot Study, Praveen Kumar Patel, Anuj Kishor Shukla, Varun Sachan, Paawan Sharma, Sonal Singh, Swapnil Saxena, Ramanpal S Makkad

Faculty, Staff and Student Publications

AIM: Telemedicine has emerged as a potential solution to enhance postoperative follow-up care after dental implant surgery, offering the convenience of remote monitoring and reduced need for in-person visits.

MATERIALS AND METHODS: Participants were randomly assigned to either the telemedicine group (n = 15) or the in-person group (n = 15). In the telemedicine group, patients received remote follow-up care through virtual consultations, during which they could communicate their concerns and share images of the surgical site. The in-person group received standard in-person follow-up visits. Patient satisfaction was measured using a standardized survey, with responses collected on a Likert scale. …


Immediate Loading Of Four Single Piece Compressive Implant For Bar-Retained Mandibular Complete Overdenture: A Study Of Peri-Implant Marginal Bone Loss And Implant Stability (A Randomized Clinical Trial), Mirna A. Maged, Mohamed Shady, Islam Kandil, Ahmed Habib Jan 2024

Immediate Loading Of Four Single Piece Compressive Implant For Bar-Retained Mandibular Complete Overdenture: A Study Of Peri-Implant Marginal Bone Loss And Implant Stability (A Randomized Clinical Trial), Mirna A. Maged, Mohamed Shady, Islam Kandil, Ahmed Habib

Mansoura Journal of Dentistry

Objective: Clinical and Radiographic evaluation of bar-retained mandibular overdenture retained by four single-piece compressive implants regarding bone loss and implant stability.

Materials and methods: Fifteen completely edentulous patients with mandibular knife edge ridge anteriorly were chosen, for all patients, compressive implants were installed in the inter-foramina areas and immediately loaded with mandibular complete overdenture housing three peek clips and retained by Co-Cr bar, implant stability was measured using periotest at insertion day T0, 3and 6 months after insertion (T3, T6), Vertical bone height changes around supporting dental implants were evaluated using CBCT x-ray at insertion day (T0), 6 …


Periodontal Health In End-Stage Renal Disease Patients Undergoing Hemodialysis, Hosam Nagy, Wafaa Saleh, Ghada El Kannishy, Jilan Mohamed Youssef Jan 2024

Periodontal Health In End-Stage Renal Disease Patients Undergoing Hemodialysis, Hosam Nagy, Wafaa Saleh, Ghada El Kannishy, Jilan Mohamed Youssef

Mansoura Journal of Dentistry

Aim of the study: The aim of this study is to evaluate periodontal health status of the hemodialysis (HD) patients and to examine the relation between Russel periodontal index (RPI) and laboratory and inflammatory markers and nutritional status in this group of patients.

Methods: A cross-sectional study was conducted on a group of patients (n=43, mean age 51.4±14.9 years) recruited from the Mansoura university Nephrology and Dialysis Unit (MNDU). Periodontal examination was performed using Russel periodontal index (RPI). Various laboratory and inflammatory markers were recorded, including routine biochemical and hematological data as well as serum parathyroid hormone, ferritin, and highly …


Omega Roll-Envelope Flap Versus Free Sub-Epithelial Connective Tissue Graft In Thin Periodontal Phenotype In Stage Ii Implant Surgery: Randomized Controlled Clinical Trial, Ahmed Hosney Fawzy, Mohamed Abdel Raheem Al Shahat, Mohamed Ellayeh, Eman M. Abdulhady Jan 2024

Omega Roll-Envelope Flap Versus Free Sub-Epithelial Connective Tissue Graft In Thin Periodontal Phenotype In Stage Ii Implant Surgery: Randomized Controlled Clinical Trial, Ahmed Hosney Fawzy, Mohamed Abdel Raheem Al Shahat, Mohamed Ellayeh, Eman M. Abdulhady

Mansoura Journal of Dentistry

Objective: The objective of this randomized clinical trial (RCT) was to analyze the clinical outcomes of labial gingival tissue augmentation throughout stage II implant surgery in subjects with thin gingival phenotype (GP) using the free sub-epithelial connective tissue graft (FSCTG) versus Omega roll envelop flap technique (OREF).

Subjects and Methods: Sixteen patients with thin GP (˂ 1.5 mm) got 20 implants in this 6—month follow up RCT and split into two groups. 1) Group I: 8 patients got 10 implants in stage I surgery and got OREF for labial soft tissue augmentation in stage II surgery. 2) Group II: 8 …


Peri-Implant Soft Tissue Changes And Patient Satisfaction Of Two Implants Retained Complete Mandibular Overdenture With All-Peek Versus All-Zirconia Telescopic Attachments, Mahmoud Abdelmoghny Elshabrawy Shawaly, Wael Sayed Ahmed, Abdallah Mohammed Ibrahim, Radwa Mohsen Kamal Emera Jan 2024

Peri-Implant Soft Tissue Changes And Patient Satisfaction Of Two Implants Retained Complete Mandibular Overdenture With All-Peek Versus All-Zirconia Telescopic Attachments, Mahmoud Abdelmoghny Elshabrawy Shawaly, Wael Sayed Ahmed, Abdallah Mohammed Ibrahim, Radwa Mohsen Kamal Emera

Mansoura Journal of Dentistry

Objective: this clinical study aimed to evaluation of soft tissue changes of the peri -implant area and patient satisfaction for two implants assisted overdenture with all-PEEK versus all-zirconia telescopic attachment.

Materials and Methods: Ten patients who were complete edentulous and had a history of complaining about the instability and poor retention of their mandibular complete dentures were chosen. Each patient received a conventional denture for one month then two dental implants were drilled in the mandibular canine area. Implant overdentures were retained by using telescopic attachments. According to the telescopic attachment coping material type, the patients were grouped as: Group …


The Effect Of Calcium Hydroxide Intracanal Medicament On Root Dentine Microhardness: An In Vitro Study, Reem I. Taha, Noha A El-Wassefy, Amany E. Badr Jan 2024

The Effect Of Calcium Hydroxide Intracanal Medicament On Root Dentine Microhardness: An In Vitro Study, Reem I. Taha, Noha A El-Wassefy, Amany E. Badr

Mansoura Journal of Dentistry

Objective: To evaluate the root dentine microhardness after using calcium hydroxide (Ca (OH)2) intracanal medicament. Materials and methods: Forty single-rooted teeth were sectioned at the cemento-enamel junction level and the root canals were prepared till apical size of #30. The prepared teeth were divided into 2 groups (n=20): no medicament (control) group and Ca (OH)2 group. After seven days, medicaments were removed using standardized volume of irrigation. All teeth were sectioned in a bucco-lingual plane and embedded in acrylic resin horizontally with the dentine surfaces exposed. Using Vickers microhardness tester with magnification of 100× and a load of 25 g …


Clinical And Radiographical Assessment Of Platelet Rich Fibrin (Prf) Versus Placental Extract Gel On Delayed Implant Placement: Comparative Clinical Split Mouth Study, Eman Shawki Mira, Ayman Abdel Rahim Mohammed Elkashty, Ahmed Mohammed Saaduddin Sapri Jan 2024

Clinical And Radiographical Assessment Of Platelet Rich Fibrin (Prf) Versus Placental Extract Gel On Delayed Implant Placement: Comparative Clinical Split Mouth Study, Eman Shawki Mira, Ayman Abdel Rahim Mohammed Elkashty, Ahmed Mohammed Saaduddin Sapri

Mansoura Journal of Dentistry

Purpose: This study was established to compare Platelet Rich Fibrin (PRF) versus Placental Extract Gel on delayed implant placement.

Patient and Methods: Sixteen patients aged from 35-45 years were selected for that study. Split mouth design was performed, placing PFR on one side of the mouth while placing placental extract gel on the other side of the mouth during implant insertion. Follow -up was done for all the cases 6 months postoperatively both clinically and radiographically. When comparing two groups within the same timepoint, the student unpaired t-test was employed, and when comparing two timepoints within the same group in …


Comparative Analysis Employing Digital Data Acquisition Of Digital Complete Denture Impression Against Conventional Impression: Clinical Trials, Eman Yasser Abdullah, Abdullah Mohammed Ibrahim Salem, Aisha Zakaria Hashem Mostafa Jan 2024

Comparative Analysis Employing Digital Data Acquisition Of Digital Complete Denture Impression Against Conventional Impression: Clinical Trials, Eman Yasser Abdullah, Abdullah Mohammed Ibrahim Salem, Aisha Zakaria Hashem Mostafa

Mansoura Journal of Dentistry

Objective: To compare the accuracy between complete denture impressions made on digitally constructed and conventionally constructed custom trays with two impression materials.

Materials and Methods: Eight completely edentulous patients were selected; intra oral scanning was done for all patients to record digital impression and saved in standard tessellation language. The scanned data was imported to 3D printer to fabricate digital cast and was imported to custom tray design software to design the special tray. The printed cast was duplicated to fabricate a visible light cured acrylic resin tray. All patients received 8 trays (4 for each arch). Two impression materials …


Maximum Biting Force Evaluation Of Clasped And Claspless Mandibular Kennedy Class I Implant Supported Partial Overdenture With Rigid And Flexible Denture Bases: Case Series Study, Saif M. Sami, Ziad M. Elmissiry, Fatma Mahanna, Ashraf A. Gebreel Jan 2024

Maximum Biting Force Evaluation Of Clasped And Claspless Mandibular Kennedy Class I Implant Supported Partial Overdenture With Rigid And Flexible Denture Bases: Case Series Study, Saif M. Sami, Ziad M. Elmissiry, Fatma Mahanna, Ashraf A. Gebreel

Mansoura Journal of Dentistry

Objectives: Evaluation of clasped and clasp-less mandibular Kennedy class I implant supported partial overdenture with acrylic or flexible denture bases by maximum biting force measurement.

Materials and methods: Six partially edentulous male patients with mandibular Kennedy class I and completely edentulous maxilla were selected. Two implants were installed on mandibular first molar areas. Patients were classified based on the duration of their mandibular RPD use, which was characterized by two different denture bases and clasp statuses. Group 1 received metallic implant-assisted removable partial overdentures with acrylic denture bases and combination clasps for one month, then the retentive arm clasp was …


Effect Of Adjunctive Incorporation Of Nanoparticles Of Amorphous Calcium Phosphate And Chlorhexidine On Properties Of An Etch-And-Rinse Bonding Agent, Hussein Elshikha, Elsayed Gad, Noha Sheta Jan 2024

Effect Of Adjunctive Incorporation Of Nanoparticles Of Amorphous Calcium Phosphate And Chlorhexidine On Properties Of An Etch-And-Rinse Bonding Agent, Hussein Elshikha, Elsayed Gad, Noha Sheta

Mansoura Journal of Dentistry

Objective: To assess the effect of the addition of nanoparticles of amorphous calcium phosphate (NACP) and chlorhexidine (CHX) on the properties of an etch-and-rinse adhesive regarding the bond strength to caries-affected dentine (CAD) and the NACP remineralization efficacy.

Materials and Methods: Dentine surfaces from 80 human molars were subjected to pH cycling and then divided into 4 groups (n=20): adhesive without additives (control group), 5% wt/wt NACP added to the adhesive (NACP group), 0.1% CHX added to the adhesive (CHX group), and addition of 5%wt/wt NACP and 0.1% CHX to the adhesive (NACP+CHX group). After acid etching, the adhesive for …


The Impact Of Occlusal Splint Therapy And Vitamin D On The Management Of Temporomandibular Disorders, Mostafa S. Swedan, Magdy Mohamed Zaky Hussein, Sherin Fathy Donia, Mohamed Tarek Hussein Khater Jan 2024

The Impact Of Occlusal Splint Therapy And Vitamin D On The Management Of Temporomandibular Disorders, Mostafa S. Swedan, Magdy Mohamed Zaky Hussein, Sherin Fathy Donia, Mohamed Tarek Hussein Khater

Mansoura Journal of Dentistry

Objective: The purpose of this study is to evaluate the Vitamin D supplementation as an adjuvant therapy for stabilization splint in patients exhibiting temporomandibular disorders (TMD).

Materials and Methods: This study involved 100 TMD divided into two equal groups each of 50 patients; group 1: treated by occlusal splint plus vit D and group 2: treated by vitamin D only. All patients in adult age, more than 18 years. All patients were accepted without regard to their financial situation, caste, gender, or religion. Less than 30 ng/mL of vitamin D was present, the teeth were either completely dentate or had …


Comparison Between Injectable Platelet Rich Fibrin With Collagen Carrier And Β-Tricalcium Phosphate In Lateral Maxillary Sinus Lift With Simultaneous Implant Placement, Ahmed Adel Refaat, Noha Ahmed Mansour, Sally Awad Jan 2024

Comparison Between Injectable Platelet Rich Fibrin With Collagen Carrier And Β-Tricalcium Phosphate In Lateral Maxillary Sinus Lift With Simultaneous Implant Placement, Ahmed Adel Refaat, Noha Ahmed Mansour, Sally Awad

Mansoura Journal of Dentistry

Objective: This study aimed to compare injectable PRF (I-PRF) with a collagen carrier and β-Tricalcium Phosphate (β-TCP) for maxillary sinus floor augmentation (MSFA) with simultaneous implant placement.

Materials and methods: Fourteen patients with missed maxillary posterior teeth and 3-5 mm residual bone height (RBH) were selected to perform lateral MSFA with simultaneous implant placement. A total of 18 sites (implants) in 13 patients were qualified for analysis, 10 sites with I-PRF and collagen carrier (group I) and 8 sites with β-TCP (group II). Six months later, implant stability was recorded, and all sites were analyzed using cone-beam computed tomography (CBCT) …


Effect Of Debonding Methods Of Metallic Orthodontic Bracket Bonded To Zirconia On Its Surface Topography, Dina A. Elbialy, Marwa M. Wahsh, Noha E, Sabet, Ghada A. Hussein Jan 2024

Effect Of Debonding Methods Of Metallic Orthodontic Bracket Bonded To Zirconia On Its Surface Topography, Dina A. Elbialy, Marwa M. Wahsh, Noha E, Sabet, Ghada A. Hussein

Mansoura Journal of Dentistry

Objectives: to evaluate the effect of debonding methods of metallic orthodontic bracket bonded to monolithic zirconia restoration on it’s surface topography. Materials and Methods: Twenty-eight zirconia ceramic restorations were prepared and air abraded. Then twenty-eight metal orthodontic brackets were bonded using MDP containing bond for group M and Non-MDP containing bond for group N. All bonded slices were aged by thermocycling for 5000 cycles. Debonding of the brackets were done by two methods subgroup (L) the brackets was debonded by LASER and subgroup (C) the brackets debonded by conventional bracket removal plier. Results: Regarding MDP-containing Bond: The mean surface roughness …


Clinical Outcomes And Implant Stability Changes Associated With Immediately Loaded Implant Of Two Different Types Inserted In Posterior Maxilla, Hossam Mohammed Kamal, Mohamed Zaghloul Amer, Walid Abd El-Ghafar Al-Zordk, Noha Ahmed Mansour Jan 2024

Clinical Outcomes And Implant Stability Changes Associated With Immediately Loaded Implant Of Two Different Types Inserted In Posterior Maxilla, Hossam Mohammed Kamal, Mohamed Zaghloul Amer, Walid Abd El-Ghafar Al-Zordk, Noha Ahmed Mansour

Mansoura Journal of Dentistry

Objectives: To evaluate the implant stability changes associated with immediately loaded implants with specific knife-edge threads versus implants with conventional threads inserted in the posterior maxilla.

Materials and methods: Twenty patients were selected for prosthetic replacement of missed maxillary posterior single tooth by a dental implant. Patients of this study were selected after approval of the Research Ethics Committee with code (A15030821). All patients were divided into two equal groups: Group 1 (Control group): Ten patients received 10 implants of conventional thread design. Group 2 (Study group): Ten patients receiving 10 implants with specific wide knife-edge thread design. Clinical evaluation …


Periodontal Regeneration Related To Periodontitis Treated By Garden Cress And Ozone Therapy. (Randomized Clinical &Experimental Study), Zienab S. Farid, Doaa Adel Habba, Gihan Adel Balbola, Noura Mohammed Bakr Jan 2024

Periodontal Regeneration Related To Periodontitis Treated By Garden Cress And Ozone Therapy. (Randomized Clinical &Experimental Study), Zienab S. Farid, Doaa Adel Habba, Gihan Adel Balbola, Noura Mohammed Bakr

Journal of Medicine in Scientific Research

Objective: In this article, garden cress and ozone were evaluated for their potential therapeutic properties of PDL and resorption of alveolar bone in the periodontal tissues based on rats' experimental periodontitis and to assess the clinical effectiveness of local application of garden cress and ozone for treatment and management of periodontitis patients using scaling and root planing. Methodology: Thirty mature Wistar male albino rats. Three groups of rats were formed; periodontitis without treatment, periodontitis with garden cress, and periodontitis plus ozone therapy. The present study also included thirty periodontitis Patients were randomly allocated to one of three groups of ten …


Oral And Dental Health In Systemic Sclerosis: Is It A Window To Other Systemic Affections?, Omnia A Abubakr, Taghreed F M M Mostafa, Mohamed A Hamdy Jan 2024

Oral And Dental Health In Systemic Sclerosis: Is It A Window To Other Systemic Affections?, Omnia A Abubakr, Taghreed F M M Mostafa, Mohamed A Hamdy

Journal of Medicine in Scientific Research

Background: Oral and periodontal manifestations are common in systemic sclerosis (SSc) which may result in poor nutritional status and significant morbidity. Better understanding of these manifestations is crucial for better patient outcomes. We aimed to evaluate dental and oral manifestations in patients with SSc in comparison to healthy control and to study the relationship between these findings and systemic sclerosis disease activity index, skin thickness, other systemic affection, as well as the oral health-related quality of life in these patients Patients and Methods: 50 patients with SSc were included in this case-control study (Group A) and 50 apparently healthy controls …


A Pthrp Gradient Drives Mandibular Condylar Chondrogenesis Via Runx2, C Tsutsumi-Arai, Y Arai, A Tran, M Salinas, Y Nakai, S Orikasa, W Ono, N Ono Jan 2024

A Pthrp Gradient Drives Mandibular Condylar Chondrogenesis Via Runx2, C Tsutsumi-Arai, Y Arai, A Tran, M Salinas, Y Nakai, S Orikasa, W Ono, N Ono

Faculty, Staff and Student Publications

The mandibular condylar cartilage (MCC) is an essential component of the temporomandibular joint, which orchestrates the vertical growth of the mandibular ramus through endochondral ossification with distinctive modes of cell differentiation. Parathyroid hormone–related protein (PTHrP) is a master regulator of chondrogenesis; in the long bone epiphyseal growth plate, PTHrP expressed by resting zone chondrocytes promotes chondrocyte proliferation in the adjacent layer. However, how PTHrP regulates chondrogenesis in the MCC remains largely unclear. In this study, we used a Pthrp-mCherry knock-in reporter strain to map the localization of PTHrP+ cells in the MCC and define the function of PTHrP in the …


The Impact Of Gestational Diabetes Mellitus And Maternal Oral Microbiome: A Scoping Review, Jaclyn P. Langan Jan 2024

The Impact Of Gestational Diabetes Mellitus And Maternal Oral Microbiome: A Scoping Review, Jaclyn P. Langan

Honors Undergraduate Theses

Background: Gestational diabetes mellitus (GDM) is a common pregnancy-related metabolic disorder associated with adverse maternal and fetal outcomes. Recent research has highlighted the potential role of the oral microbiome in the pathophysiology of various systemic conditions, including diabetes mellitus. However, the impact of GDM on the maternal oral microbiome remains relatively understudied. Understanding alterations in the oral microbiome during pregnancy complicated by GDM could provide valuable insights into the mechanistic links between systemic metabolic disorders and oral health.

Objective: The objective of this scoping review was to comprehensively examine the existing literature on the relationship between GDM and maternal oral …


Pdgfra And B Copositive Fibroblasts Drive Fibrosis In Mouse Salivary Glands Through Tgfβ Signaling, Renae Williams Atkinson Jan 2024

Pdgfra And B Copositive Fibroblasts Drive Fibrosis In Mouse Salivary Glands Through Tgfβ Signaling, Renae Williams Atkinson

Electronic Theses & Dissertations (2024 - present)

Fibrosis is of significant concern to the medical community as numerous disease processes are characterized by progressive fibrosis leading to organ damage. We begin the process of examining the mechanism of fibrosis to salivary gland hypofunction and briefly consider Sjögren’s Disease (SjD). Method: We employed single-cell RNA sequencing data from a reversible mouse salivary gland injury model and from NOD/ShiLtJ mice, a model of secondary SjD. We performed treatment comparisons with the help of Seurat dotplots and UMAPS. Using differential gene expression analysis and the publicly available R packages: clusterProfiler, WikiPathways and Cytoscape, we identified the processes and pathways …


Fixed Detachable Prosthesis Versus Implant-Supported Overdenture For Rehabilitation Of Edentulous Maxilla Opposing 2-Implant Mandibular Overdenture: A Cross-Over Study Of Chewing Efficiency And Maximum Bite Force, Fatma Mahanna Jan 2024

Fixed Detachable Prosthesis Versus Implant-Supported Overdenture For Rehabilitation Of Edentulous Maxilla Opposing 2-Implant Mandibular Overdenture: A Cross-Over Study Of Chewing Efficiency And Maximum Bite Force, Fatma Mahanna

Mansoura Journal of Dentistry

Objective: This study assessed the chewing efficiency and maximum bite force of maxillary implant-supported bar overdentures, and fixed hybrid prostheses opposed by a mandibular overdenture supported by 2 implants. Materials and methods: Six completely edentulous patients enrolled from a previous study installed with a mandibular overdenture comprising two implants. Four parallel maxillary implants were placed in the canines and second premolars region. Each patient randomly received a bar overdenture (BOD) and a fixed hybrid prosthesis (FHP). Using chewing gum and View Gum software, the chewing efficiency was assessed in terms of variance of hue (VOH). Using an occlusal force meter, …


The Effectiveness Of Dental Pulp Stem Cells-Derived Exosomes For Direct Pulp Capping: In Vitro Study, Dina A. Hammouda, Alaa M. Mansour, Mohammed E. Grawish, Ahmed R. Zaher Jan 2024

The Effectiveness Of Dental Pulp Stem Cells-Derived Exosomes For Direct Pulp Capping: In Vitro Study, Dina A. Hammouda, Alaa M. Mansour, Mohammed E. Grawish, Ahmed R. Zaher

Mansoura Journal of Dentistry

Objective: This in vitro investigation's goal was to ascertain how well dental pulp stem cell exosomes (DPSC-exo) modulate endogenous dental pulp stem cells (DPSCs) and direct their navigation toward mineralized tissue regeneration, either alone or in conjunction with mineral trioxide aggregate (MTA). Materials and methods: For this investigation, DPSCs were harvested using rat incisors. To extract exosomes from DPSCs, an ultracentrifugation method was employed. Flow cytometry was used for the characterization of DPSCs-exo, and transmission electron microscopy (TEM) was used to measure their size. DPSCs were incubated in standard culture media and split up into three groups. The first one …


Biocompatibility Evaluation Of Edta And Chitosan Nanoparticles Gel Forms: In Vivo Histopathological Study, Alaa H. Youssef, Doaa A. Labah, Abeer A. Elgendy, Amany E. Badr Jan 2024

Biocompatibility Evaluation Of Edta And Chitosan Nanoparticles Gel Forms: In Vivo Histopathological Study, Alaa H. Youssef, Doaa A. Labah, Abeer A. Elgendy, Amany E. Badr

Mansoura Journal of Dentistry

Objectives: The purpose of this study was to evaluate and compare biocompatibility of gel form chelating agents (EDTA and chitosan NPS) after implantation of polyethylene tubes in rats. Materials and methods: Twenty albino rats were included in this study. Three horizontal incisions were performed on dorsal surface of each rat to receive three polyethylene tubes as subcutaneous implants; two of them filled with tested materials and one empty tube served as control. After 2 and 4 weeks of subcutaneous implantation, 10 rats were sacrificed and implanted polyethylene tubes with surrounding tissues were dissected with 1 cm safety margin. The specimens …


Evaluation Of Double Crown Attachments Made Of Polyether –Ketoneketone Secondary Crowns Combined To Primary Crowns Of Two Different Materials For 2-Implant Retained Overdentures, Esraa Wefky Shawkat Elsaba, Noha Ahmed Mansour, Heba Nabil Awad, Radwa Mohsen Kamal Emera Jan 2024

Evaluation Of Double Crown Attachments Made Of Polyether –Ketoneketone Secondary Crowns Combined To Primary Crowns Of Two Different Materials For 2-Implant Retained Overdentures, Esraa Wefky Shawkat Elsaba, Noha Ahmed Mansour, Heba Nabil Awad, Radwa Mohsen Kamal Emera

Mansoura Journal of Dentistry

Objective: To assess the retention force using a digital forcemeter, the peri-implant soft tissue health, and the periimplant marginal bone loss of two implant-retained mandibular complete overdentures with double crown attachments made of polyetherketone- ketone (PEKK) secondary crowns combined to primary crowns of two different materials Methods Fourteen healthy male patients, ages 55 to 65 on average, who were entirely edentulous • group I: seven patients were given a mandibular overdenture that was held by two im plants and had telescopic attachments for a primary zirconiabased coping and a secondary PEKK-based coping against a maxillay full denture. • Group II: …


Correlation Of Mandibular Advancement Device For Management Of Obstructive Sleep Apnea And Body Mass Index And Oxygen Saturation. Clinical Prospective Study, Hala G. Elzayady, Noha H. El-Shaheed, Aida M. Yousef, Aisha Z. H. Mostafa Jan 2024

Correlation Of Mandibular Advancement Device For Management Of Obstructive Sleep Apnea And Body Mass Index And Oxygen Saturation. Clinical Prospective Study, Hala G. Elzayady, Noha H. El-Shaheed, Aida M. Yousef, Aisha Z. H. Mostafa

Mansoura Journal of Dentistry

Objective: Reduced oxygen saturation (SaO2 %) is a clinical sign of obstructive sleep apnea (OSA), It is regarded as one of the medical problems. The study's goal was to investigate the connection between oxygen saturation, body mass index (BMI), and using the Mandibular Advancement Device (MAD) to manage people with obstructive sleep apnea.

Materials and Methods: From the outpatient clinic of the Sleep Medicine Unit, Chest Medicine Department, Faculty of Medicine, Mansoura University, twenty patients with obstructive sleep apnea were chosen. A mandibular advancement was utilized to treat obstructive sleep apnea. Using polysomnography, periodic oxygen saturation and body …


The Use Of Expanded Polytetrafluoroethylene Membrane (E-Ptfe) As A Barrier Membrane For Critical Size Defects Following Jaw Cyst Enucleation, Sara Salem, Ayman Ahmed Yaseen, Mohamed Abdel-Monem Tawfik Jan 2024

The Use Of Expanded Polytetrafluoroethylene Membrane (E-Ptfe) As A Barrier Membrane For Critical Size Defects Following Jaw Cyst Enucleation, Sara Salem, Ayman Ahmed Yaseen, Mohamed Abdel-Monem Tawfik

Mansoura Journal of Dentistry

Purpose: The use of bone graft following cyst enucleation could lead to infection so, this study was conducted to investigate impact of (e-PTFE) membrane alone without bone graft in promoting bone healing compared to the spontaneous bone regeneration after cyst enucleation.

Materials and methods: Sixteen intra-bony cysts in 16 patients (6 males, 10 females) were included. In study group (e-PTFE) barrier membrane was used alone after enucleation while, in control group the conventional technique was used. The follow up Period was 6 and 12 months postoperatively. Clinically, pain, soft tissue healing, and membrane exposure were assessed. Radiographically, CBCT scans were …


Variations In Root Anatomy Of Mandibular Third Molars Using Cone Beam Computed Tomography And Personal Identification: A Cross-Sectional Study Amongst Egyptians, Shimaa M Motawei, Bassant Mowafey, Fatma Ata, Mohammad Osama, Osama A. Shabka Jan 2024

Variations In Root Anatomy Of Mandibular Third Molars Using Cone Beam Computed Tomography And Personal Identification: A Cross-Sectional Study Amongst Egyptians, Shimaa M Motawei, Bassant Mowafey, Fatma Ata, Mohammad Osama, Osama A. Shabka

Mansoura Journal of Dentistry

Objective: To assess the root canal anatomy and root morphology of mandibular third molars (MTMs) in the Egyptians using cone beam computed tomography (CBCT). Methods: A total of 338 CBCT scans of mandibular third molars (MTMs) were collected and evaluated regarding the related root(s) number and root canal configuration. Statistical analysis highlighted differences between different categories and their prevalence among genders and sides (significance level was set at p < 0.05). Data were presented as frequency and percentage values and were analyzed using a chisquare test followed by pairwise comparisons utilizing multiple Fisher’s exact tests with Bonferroni correction. The significance level was set at p < 0.05 within all tests. Results: A total of 338 MTMs [186 (55%) from male patients, 152 (45%) from female patients] from 279 patients (151 male and 128 female) were evaluated. The majority (82.84%) of the studied MTMs had two roots. single-, triple-, and quadruple-rooted MTMs were less common than double-rooted MTMs, accounting for 10.1%, 5.33%, and 1.18% of the sample, respectively. Regarding root canal anatomy, Vertucci type I was the most seen morphology (61% of all MTMs roots mostly in distal roots (42.41%), followed by Vertucci type III (13.08%). The chi-square test showed no significant difference between males and females (p=0.36) or between the right side and left sides (p=0.691) regarding the number of roots. Conclusion: Within the limitations of the present study, the findings conclude significant variability in the root and root canal anatomy of mandibular third molars (MTMs) within the Egyptian sub-population.


Osteocalcin As A Gingival Crevicular Fluid Biomarker For Periodontitis Among Egyptian Population Sample- Controlled Clinical Trial, Mohamed Al Bahrawy, Sahar Abdel Rauf, Eman M. Abdulhady Jan 2024

Osteocalcin As A Gingival Crevicular Fluid Biomarker For Periodontitis Among Egyptian Population Sample- Controlled Clinical Trial, Mohamed Al Bahrawy, Sahar Abdel Rauf, Eman M. Abdulhady

Mansoura Journal of Dentistry

Objectives This clinical trial aimed to evaluate osteocalcin levels in healthy and diseased periodontium and to correlate the changes in its levels with the changes in the clinical and radiographic parameters before and after treatment. Subject & Methods Double blind clinical trial, 40 patients divided into 3 groups; 15 patients diagnosed as periodontitis stage III grade B, 15 patients diagnosed as periodontitis stage III grade C, 10 healthy cases as control. Clinical parameters namely plaque index (PI), gingival index (GI), periodontal pocket depth (PPD), clinical attachment loss (CAL), radiographic examination, beside gingival crevicular fluid (GCF) samples collection for osteocalcin (OC) …


Mechanical And Optical Behavior Of Two Lithium Silicate-Based Glass Ceramics After Aging In Intra-Oral Simulating Condition, Sherief Mowafy, Salwa Abdel Raouf Elnegoly, Hagag Abdelkader Mohammed Jan 2024

Mechanical And Optical Behavior Of Two Lithium Silicate-Based Glass Ceramics After Aging In Intra-Oral Simulating Condition, Sherief Mowafy, Salwa Abdel Raouf Elnegoly, Hagag Abdelkader Mohammed

Mansoura Journal of Dentistry

Aim This study evaluated the mechanical and optical properties of Zirconia-reinforced lithium disilicate (ZLS) and lithium disilicate (LS) glass ceramics after immersion in artificial saliva solutions with varying pH. Methods A total of 104 samples were fabricated from Vita Suprinity (ZLS) and IPS E.max CAD (LS). Samples were divided into test and control groups, with the test group further divided into neutral (7.2), acidic (5.8), and basic (8.3) pH subgroups. Samples were immersed for 24 hours at 37°C and evaluated for microhardness, fracture toughness, and color stability. Results Significant differences were found in the properties of both materials across the …