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Tinnitus And Decreased Subcortical And Cortical Inhibition, Kenneth Vincent Morse

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Background: The perception of tinnitus may be triggered by a reduction in inhibitory function in the central auditory nervous system. Evidence, primarily from invasive studies of animal models of tinnitus, indicates that these changes occur at both the subcortical and cortical level. Auditory evoked potential (AEP) indices of subcortical inhibition [auditory brainstem response (ABR) 〖"V/I" 〗_"amp ratio" ] and cortical inhibition [cortical auditory evoked potential (CAEP) sensory gating ratios] may provide an objective index of whether reduced subcortical and/or cortical inhibition is associated with tinnitus perception in humans. The aims of this study were to assess whether ABR and/or CAEP …