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Articles 1 - 5 of 5
Full-Text Articles in Chemicals and Drugs
Prefrontal Cortex Glutamatergic Adaptations In A Mouse Model Of Alcohol Use Disorder, Mahum T. Siddiqi, Dhruba Podder, Amanda R. Pahng, Alexandria C. Athanason, Tali Nadav, Chelsea Cates-Gatto, Max Kreifeldt, Candice Contet, Amanda J. Roberts, Scott Edwards, Marisa Roberto, Florence P. Varodayan
Prefrontal Cortex Glutamatergic Adaptations In A Mouse Model Of Alcohol Use Disorder, Mahum T. Siddiqi, Dhruba Podder, Amanda R. Pahng, Alexandria C. Athanason, Tali Nadav, Chelsea Cates-Gatto, Max Kreifeldt, Candice Contet, Amanda J. Roberts, Scott Edwards, Marisa Roberto, Florence P. Varodayan
School of Graduate Studies Faculty Publications
Alcohol use disorder (AUD) produces cognitive deficits, indicating a shift in prefrontal cortex (PFC) function. PFC glutamate neurotransmission is mostly mediated by α-amino-3‑hydroxy-5-methyl-4-isoxazolepropionic acid-type ionotropic receptors (AMPARs); however preclinical studies have mostly focused on other receptor subtypes. Here we examined the impact of early withdrawal from chronic ethanol on AMPAR function in the mouse medial PFC (mPFC). Dependent male C57BL/6J mice were generated using the chronic intermittent ethanol vapor-two bottle choice (CIE-2BC) paradigm. Non-dependent mice had access to water and ethanol bottles but did not receive ethanol vapor. Naïve mice had no ethanol exposure. We used patch-clamp electrophysiology to measure …
Addressing A Lack Of Education Surrounding Fentanyl Use And Recovery, Nicole Sala, Luciana Gonzalez, Caroline Dorvilien, Teo Keilwitz, Maddy Terhune, Portia Forson
Addressing A Lack Of Education Surrounding Fentanyl Use And Recovery, Nicole Sala, Luciana Gonzalez, Caroline Dorvilien, Teo Keilwitz, Maddy Terhune, Portia Forson
Nursing Leadership in Community Engagement Projects
Nursing Leadership Executive Summary: Addressing a Lack of Education Surrounding Fentanyl Use and Recovery
Our project focused on assisting a nonprofit organization who exists to serve the most vulnerable of families in the Seattle area. They offer a number of programs including a mobile outreach team that seeks to bring resources to families, a program for families which provides the opportunity for new mothers to bond with their newborn, and another program which assists families with medically fragile children to find healthcare resources, and more. Our team was made up of six students from the Lydia Green Nursing Program at …
Drug Addiction & Mental Health, Tyler Burkholder
Drug Addiction & Mental Health, Tyler Burkholder
English Department: Research for Change - Wicked Problems in Our World
Drugs have a serious effect on our mental health, and mental health has a major effect on drug abuse and addiction. There is a reason so many drug users usually need to keep going back to rehab. It is because drugs affect mental health to a point where you aren’t the same person during and even after drug addiction. Poor mental health also can be a major cause influencing people to start doing drugs. People with depression, anxiety disorders, mood disorders are more prone to drug use. That is why we need to make it a public policy to screen …
Telehealth Improves Access To Treatment For Substance Use Disorder, Jeremy Kourvelas, Carole Myers Phd, Katie Cahill Phd, Stephen Loyd Md, Jennifer Tourville Dnp
Telehealth Improves Access To Treatment For Substance Use Disorder, Jeremy Kourvelas, Carole Myers Phd, Katie Cahill Phd, Stephen Loyd Md, Jennifer Tourville Dnp
SMART Policy Briefs
No abstract provided.
The Winding Road To Relapse: Forging A New Understanding Of Cue-Induced Reinstatement Models And Their Associated Neural Mechanisms, Mark D. Namba, Seven E. Tomek, M. Foster Olive, Joshua S. Beckmann, Cassandra D. Gipson
The Winding Road To Relapse: Forging A New Understanding Of Cue-Induced Reinstatement Models And Their Associated Neural Mechanisms, Mark D. Namba, Seven E. Tomek, M. Foster Olive, Joshua S. Beckmann, Cassandra D. Gipson
Psychology Faculty Publications
In drug addiction, cues previously associated with drug use can produce craving and frequently trigger the resumption of drug taking in individuals vulnerable to relapse. Environmental stimuli associated with drugs or natural reinforcers can become reliably conditioned to increase behavior that was previously reinforced. In preclinical models of addiction, these cues enhance both drug self-administration and reinstatement of drug seeking. In this review, we will dissociate the roles of conditioned stimuli as reinforcers from their modulatory or discriminative functions in producing drug-seeking behavior. As well, we will examine possible differences in neurobiological encoding underlying these functional differences. Specifically, we will …