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2022

COVID-19

Articles 1 - 9 of 9

Full-Text Articles in Chemicals and Drugs

A Changing Epidemic And The Rise Of Opioid-Stimulant Co-Use, Saeed Ahmed, Zouina Sarfraz, Azza Sarfraz Jul 2022

A Changing Epidemic And The Rise Of Opioid-Stimulant Co-Use, Saeed Ahmed, Zouina Sarfraz, Azza Sarfraz

Department of Paediatrics and Child Health

No abstract provided.

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Early Th2 Inflammation In The Upper Respiratory Mucosa As A Predictor Of Severe Covid-19 And Modulation By Early Treatment With Inhaled Corticosteroids: A Mechanistic Analysis, Jonathan R. Baker, Mahdi Mahdi, Dan V. Nicolau, Sanjay Ramakrishnan, Peter J. Barnes, Jodie L. Simpson, Steven P. Cass, Richard E. K. Russell, Louise E. Donnelly, Mona Bafadhel Jun 2022

Early Th2 Inflammation In The Upper Respiratory Mucosa As A Predictor Of Severe Covid-19 And Modulation By Early Treatment With Inhaled Corticosteroids: A Mechanistic Analysis, Jonathan R. Baker, Mahdi Mahdi, Dan V. Nicolau, Sanjay Ramakrishnan, Peter J. Barnes, Jodie L. Simpson, Steven P. Cass, Richard E. K. Russell, Louise E. Donnelly, Mona Bafadhel

Research outputs 2022 to 2026

Background: Community-based clinical trials of the inhaled corticosteroid budesonide in early COVID-19 have shown improved patient outcomes. We aimed to understand the inflammatory mechanism of budesonide in the treatment of early COVID-19. Methods: The STOIC trial was a randomised, open label, parallel group, phase 2 clinical intervention trial where patients were randomly assigned (1:1) to receive usual care (as needed antipyretics were only available treatment) or inhaled budesonide at a dose of 800 μg twice a day plus usual care. For this experimental analysis, we investigated the nasal mucosal inflammatory response in patients recruited to the STOIC trial and in …

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The Use Of Nebulizer Medications As A Possible Treatment For Covid-19, Jacob Kaufman May 2022

The Use Of Nebulizer Medications As A Possible Treatment For Covid-19, Jacob Kaufman

Honors College Theses

For the past few years, the COVID-19 pandemic has been the focal point in healthcare and research. This disease has permanently changed daily life and left a historic impact on the world. Most people have felt the effects of this pandemic either directly, via infection, or indirectly, via change in workflow, financial impact, etc. The main question for this virus still remains today; how do we treat this illness effectively? While many ideas are being tested and suggested, a definite answer has yet to be procured. Vaccine rates are climbing on a daily basis, serving as the first and most …

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A Case Report On Causes Of Covid-19 Induced Psychosis And Treatments, Jennifer Pires, Steven Sarner May 2022

A Case Report On Causes Of Covid-19 Induced Psychosis And Treatments, Jennifer Pires, Steven Sarner

Rowan-Virtua Research Day

COVID-19 is a viral infection that is caused by an RNA virus in a subfamily of Coronaviridae named severe acute respiratory syndrome (SARS CoV 2). The family also includes severe acute respiratory syndrome coronavirus (SARS CoV) and middle east respiratory syndrome coronavirus (MERS CoV) which have previously been shown to cause respiratory symptoms and psychosis with immunoreactivity to IgG.

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Case Report: Covid Arm (Covid Vaccine Arm), Joseph Pagano, James Espinosa, Alan Lucerna, Henry Schuitema May 2022

Case Report: Covid Arm (Covid Vaccine Arm), Joseph Pagano, James Espinosa, Alan Lucerna, Henry Schuitema

Rowan-Virtua Research Day

We report the case of a 38-year-old male physician who was vaccinated with the Pfizer vaccine. He experienced arm pain and swelling on the vaccinated arm as well as systemic symptoms, including fever, chills, headache and weakness. The systemic symptoms improved after the use of oral prednisone. A review of the literature on the COVID vaccine is presented.

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Tackling Protein-Calorie Malnutrition During World Crises, Zahra Ali Padhani, Jai K. Das, Saeed Akhtar, Tariq Ismail, Zulfiqar Ahmed Bhutta Mar 2022

Tackling Protein-Calorie Malnutrition During World Crises, Zahra Ali Padhani, Jai K. Das, Saeed Akhtar, Tariq Ismail, Zulfiqar Ahmed Bhutta

Woman and Child Health

Undernutrition is still highly prevalent in developing countries and leads to a multitude of problems as it weakens the immune system, which leads to increased risk of infections and diet-related diseases. COVID-19 has worsened the existing situation and has resulted in unprecedented health, social, and economic disruptions across the world. Before COVID-19, about 54% children under 5 years were moderately or seriously malnourished, and after the COVID-19 pandemic, early estimates suggest that an additional 2.6 million children were stunted; 9.3 million were wasted, with an addition of 2.1 million maternal anemia cases; 168,000 child deaths; and USD 29.7 billion in …

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Use Of Steroids In Covid-19 Patients: What Is Known?, Syed Muhammad Mustahsan, Marzia Tahir, Emaduddin Siddiqui Mar 2022

Use Of Steroids In Covid-19 Patients: What Is Known?, Syed Muhammad Mustahsan, Marzia Tahir, Emaduddin Siddiqui

Department of Emergency Medicine

COVID-19 pandemic has exaggerated the role of steroids in the standard of care despite minimum direct evidence of their efficacy in COVID-19 patients and their well-known adverse effects. The literature abounds on the side effects of steroids affecting different organ systems of the body. COVID-19 patients, who are on long-term steroids, are more susceptible to their adverse effects. We, herein, briefly review the potential uses and the adverse effects of steroids on different organ systems of the body. Key Words: Steroids, COVID-19, Adverse effects.

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Learning From South Korea’S Covid-19 Response: Why Centralizing The United States Public Health System Is Essential For Future Pandemic Responses, Meghan Ricci Jan 2022

Learning From South Korea’S Covid-19 Response: Why Centralizing The United States Public Health System Is Essential For Future Pandemic Responses, Meghan Ricci

Seattle Journal of Technology, Environmental & Innovation Law

The COVID-19 pandemic revealed stark differences in governmental preparedness across the globe. The United States, once thought of as a global leader in public health, had the theoretical skill and efficiency to handle the pandemic but failed to utilize those skills and resources during an actual health crisis. In the spring of 2020, everyone watched the U.S.’s reaction to the unfolding of the COVID-19 pandemic due to its historic placeholder as a global leader and innovator. However, the performance of the U.S. in response to the global pandemic disappointed both global commentators and U.S. citizens. This paper will compare the …

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Botanicals As Prospective Agents Against Sars-Cov-2 Virus, Vyacheslav Dushenkov, Anna Dushenkov Jan 2022

Botanicals As Prospective Agents Against Sars-Cov-2 Virus, Vyacheslav Dushenkov, Anna Dushenkov

Publications and Research

The COVID-19 high morbidity and mortality resulted in a worldwide healthcare emergency that triggered accelerated and amplified efforts in the relevant areas of health sciences research and practice. Purpose: To assess the potential role of botanicals as therapeutic agents against the SARS-CoV-2 virus. Methods: This narrative review examined the potential role of botanicals as therapeutic agents against the SARS-CoV-2 virus based on the references limited to the English language and published up to February 2022 and retrieved from common academic search engines using multiple keywords and their combinations. The scientific names of plant species were confirmed using World Flora Online …

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