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Articles 1 - 11 of 11
Full-Text Articles in Chemicals and Drugs
The Use Of Near Infrared And Microwave Sensing For On-Line Real Time Monitoring Of Moisture Content And Composition Of Powder Blend, Ryan V. Mcdonnell, Anshu Gupta, John Austin, Michael T. Harris, Gintaras V. Reklaitis
The Use Of Near Infrared And Microwave Sensing For On-Line Real Time Monitoring Of Moisture Content And Composition Of Powder Blend, Ryan V. Mcdonnell, Anshu Gupta, John Austin, Michael T. Harris, Gintaras V. Reklaitis
The Summer Undergraduate Research Fellowship (SURF) Symposium
Online process analytics has been a topic of interest by pharmaceutical companies as a method of determining how operating parameters affect the final quality of their products. One form of online process analytics that has been found to be effective is microwave sensing. While it has been found that microwave resonance sensing can be used to measure parameters such as moisture content and density, it has yet to be discovered if such sensors have the ability to measure changes in content uniformity of raw materials pharmaceutical companies use. Data was collected using a spin riffler fitted with a microwave sensor …
Cellular Uptake Mechanism Of Paclitaxel Nanocrystals, Iris K. Archer, Zhaohui Wang, Tonglei Li
Cellular Uptake Mechanism Of Paclitaxel Nanocrystals, Iris K. Archer, Zhaohui Wang, Tonglei Li
The Summer Undergraduate Research Fellowship (SURF) Symposium
Therapeutic options for metastasized human cancer in current practice remain limited and, sadly, there is no cure for metastatic cancer. The typical approach, chemotherapy, has both low efficacy due to poor drug solubility, and cytotoxic side effects to healthy tissue when delivered indiscriminately. To address both of these issues, we are pursuing the use of nanocrystal formulations of current chemotherapeutic agents as delivery platforms. Herein, we have studied cellular uptake mechanisms in cancer cells of nanocrystals of a chemotherapeutic agent, paclitaxel. Our goal in this study is to determine whether the nanocrystals can be taken up via endocytosis, especially when …
Non-Mass Transfer Limited Crystal Growth, Ryan J. Smyth, Caitlin Schram, Stephen P. Beaudoin
Non-Mass Transfer Limited Crystal Growth, Ryan J. Smyth, Caitlin Schram, Stephen P. Beaudoin
The Summer Undergraduate Research Fellowship (SURF) Symposium
There are many different active pharmaceutical ingredients (APIs) that have been discovered in research labs all around the world that can be used to treat and cure patients with a variety of different ailments. The challenge with these APIs in treatments is that they are not soluble in water, thus they low absorption into the blood stream (bio-availability). The key to making these APIs more bio-available is to understand how they grow as crystals and drop out of the aqueous solutions. One of the ways these APIs were made more bio-available is to render them amorphous and suspend them in …
Resveratrol Effects On Breast Cancer, Shelby Young
Resveratrol Effects On Breast Cancer, Shelby Young
Undergraduate Research Conference
Resveratrol (RES) is a polyphenolic compound found in 72 different plant species. Grape skins, red wine, berries, pomegranates, soybeans and peanuts are excellent sources. RES is more bioavailable in whole food form than supplemental.
The Effects Of Internal And External Support On Drinking Outcomes After Receiving A Brief Intervention For Substance Abuse, Ashley D. Jackson
The Effects Of Internal And External Support On Drinking Outcomes After Receiving A Brief Intervention For Substance Abuse, Ashley D. Jackson
Georgia State Undergraduate Research Conference
No abstract provided.
Design And Synthesis Of Hif-1 Inhibitors As Anti-Cancer Therapeutics, Zeus De Los Santos
Design And Synthesis Of Hif-1 Inhibitors As Anti-Cancer Therapeutics, Zeus De Los Santos
Georgia State Undergraduate Research Conference
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Synthesis Of Near-Infrared Heptamethine Cyanine Dyes As Biological Imaging Agents, Jordan L. Malray
Synthesis Of Near-Infrared Heptamethine Cyanine Dyes As Biological Imaging Agents, Jordan L. Malray
Georgia State Undergraduate Research Conference
No abstract provided.
The Optimization Of Pentamethine Carbocyanine Dyes By Means Of Microwave Assisted Organic Synthesis, Nicholas R. Bruschi
The Optimization Of Pentamethine Carbocyanine Dyes By Means Of Microwave Assisted Organic Synthesis, Nicholas R. Bruschi
Georgia State Undergraduate Research Conference
No abstract provided.
Polyamine-Anthracene Conjugates: The Correlation Between Interaction With Dna, Pat Activity, And Cytotoxicity, Khoa T. Nguyen
Polyamine-Anthracene Conjugates: The Correlation Between Interaction With Dna, Pat Activity, And Cytotoxicity, Khoa T. Nguyen
Georgia State Undergraduate Research Conference
No abstract provided.
Developing Pentamethine Cyanine Dyes For Photodynamic Therapy, Quoc Bao H. Nguyen
Developing Pentamethine Cyanine Dyes For Photodynamic Therapy, Quoc Bao H. Nguyen
Georgia State Undergraduate Research Conference
No abstract provided.
Endocrine Imaging Using Near-Infrared Fluorescent Pentamethine Cyanine Dyes, Tyler Dost
Endocrine Imaging Using Near-Infrared Fluorescent Pentamethine Cyanine Dyes, Tyler Dost
Georgia State Undergraduate Research Conference
No abstract provided.