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Novel Therapy For Nicotine Addiction In Alcohol Dependent Rats, Bethany Ann Stennett
Novel Therapy For Nicotine Addiction In Alcohol Dependent Rats, Bethany Ann Stennett
UNF Graduate Theses and Dissertations
The co-dependence of nicotine and alcohol addiction occurs at high rates, complicates treatment, and is often associated with significant morbidity and mortality. Treatment options of alcohol and tobacco co-dependence are limited. Currently, there are drugs available for nicotine dependence or alcohol dependence. However, there are no therapeutic drugs available on the market for the co-dependence of nicotine and alcohol. Therefore, and important opportunity of new therapeutic options and drug development has presented itself. NT69L, a non-selective neurotensin (NT) agonist, provides a potential novel therapy for nicotine addiction in alcoholics by interacting with the common neurotransmitter circuits supporting the rewarding process …