Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Nanomedicine (3)
- Nanotechnology (3)
- Amino Acids, Peptides, and Proteins (2)
- Medical Sciences (2)
- Nucleic Acids, Nucleotides, and Nucleosides (2)
-
- Other Chemicals and Drugs (2)
- Biological Phenomena, Cell Phenomena, and Immunity (1)
- Biology and Biomimetic Materials (1)
- Biomaterials (1)
- Biomedical Engineering and Bioengineering (1)
- Catalysis and Reaction Engineering (1)
- Ceramic Materials (1)
- Chemical Engineering (1)
- Chemistry (1)
- Civil and Environmental Engineering (1)
- Engineering (1)
- Environmental Engineering (1)
- Environmental Sciences (1)
- Hormones, Hormone Substitutes, and Hormone Antagonists (1)
- Inorganic Chemicals (1)
- Inorganic Chemistry (1)
- Materials Science and Engineering (1)
- Medical Biochemistry (1)
- Medical Biophysics (1)
- Medical Biotechnology (1)
- Medical Specialties (1)
- Nanoscience and Nanotechnology (1)
- Organic Chemicals (1)
- Keyword
-
- 5-fluorouracil anti-cancer drug (1)
- Adrenal gland (1)
- Band gap (1)
- Bisphenol A (1)
- CORM-3 (1)
-
- Carbon monoxide (1)
- Click chemistry (1)
- Compartment syndrome (1)
- Cyclic voltammetry (1)
- DNA (1)
- Drug delivery (1)
- Estrogen receptor (1)
- Fasciotomy (1)
- Fluorescence resonance energy transfer (FRET) (1)
- Gold nanoparticles. (1)
- Inflammation (1)
- Ion implanted; collagen type 1; helium ion (He+); nitrogen ion (N+); nanofibrous scaffold; humidity – fiber diameter correlation; Polychromatic ion beam; crosslinking; Stopping and Range of Ions in Matter (SRIM); degree of crosslinking (1)
- Magnetic ferrite-encapsulated titania nanotube arrays (1)
- Magnetic resonance imaging (1)
- Molecular beacon (1)
- Peptide Nucleic Acids (1)
- Photoconvesion efficiency (1)
- Photoelctrochemical properties (1)
- Photoinduced electron transfer (PET) (1)
- Post-synthetic modification (1)
- Pyrrolocytosine (pC) derivatives (1)
- Rehm-Weller equation (1)
- Sonic hedgehog (1)
- StAR (1)
- Stern-Volmer constant (1)
Articles 1 - 6 of 6
Full-Text Articles in Chemicals and Drugs
Fabrication And Modification Of Titania Nanotube Arrays For Harvesting Solar Energy And Drug Delivery Applications, Ahmed El Ruby Abdel Rahman Mohamed
Fabrication And Modification Of Titania Nanotube Arrays For Harvesting Solar Energy And Drug Delivery Applications, Ahmed El Ruby Abdel Rahman Mohamed
Electronic Thesis and Dissertation Repository
The fast diminishing of fossil fuels in the near future, as well as the global warming caused by increasing greenhouse gases have motivated the urgent quest to develop advanced materials as cost-effective photoanodes for solar light harvesting and many other photocatalytic applications. Recently, titania nanotube arrays (TNTAs) fabricated by anodization process has attracted great interest due to their excellent properties such as: high surface area, vertically oriented, highly organized, one-dimensional, nanotubular structure, photoactivity, chemical stability and biocompatibility. This unique combination of excellent properties makes TNTAs an excellent photoanode for solar light harvesting. However, the relatively wide band gap energy of …
Effects Of Prenatal Bisphenol A Exposure On Adrenal Gland Development And Steroidogenic Function, Samantha Medwid
Effects Of Prenatal Bisphenol A Exposure On Adrenal Gland Development And Steroidogenic Function, Samantha Medwid
Electronic Thesis and Dissertation Repository
Developmental exposure to bisphenol A (BPA), a ubiquitous endocrine disrupting chemical, is associated with organ dysfunction and diseases in adulthood. However, little is known about its effects on the adrenal glands. Therefore, this thesis addresses this important question using both in vivo and in vitro approaches. BPA at environmentally relevant doses was administrated via diet to pregnant mice from embryonic day 7.5 to birth, following which mice were switched to a standard chow. At two months postnatally, adrenal glands and blood samples were collected from adult mouse offspring for structural and functional analysis. I found that: (a) BPA increased adrenal …
Synthesis And Photophysical Studies Of Pyrrolocytosine Derivatives, Atefeh Rouhi
Synthesis And Photophysical Studies Of Pyrrolocytosine Derivatives, Atefeh Rouhi
Electronic Thesis and Dissertation Repository
Pyrrolocytosine (pC) derivatives are used in the study of nucleic acid structure, function and in the design of the hybridization probes. They have unique properties including small size and Watson-Crick base pairing capability and impressive fluorescent properties. However, they exhibit variation in the fluorescence properties upon incorporation into single-stranded DNA and double-stranded DNA.
This study analyzes the effect of the nearest neighbours on the fluorescence properties of phenylpyrrolocytosine (PhpC) and provides a guide to the proper design of the PhpC containing fluorescent probes. Moreover, the possibility of photoinduced electron transfer (PET) as the underlying mechanism of the unusual photophysical behavior …
Electrospun Collagen Nanofibers For Tissue Engineering, Nisha Sharma
Electrospun Collagen Nanofibers For Tissue Engineering, Nisha Sharma
Electronic Thesis and Dissertation Repository
Design and fabrication of the scaffold is an important part of the tissue engineering process. Nanofibrous scaffolds based on proteins are gaining increasing acceptance due to its structural similarity to the extracellular matrix. Making use of the electrospinning technique, rat tail collagen type I nanofibers were produced using a collagen in hexafluoroisopropanol (HFIP) solution. In addition to optimizing the electrospinning process parameters, the effect of humidity on fiber morphology and diameter was investigated for fiber size control for particular tissue engineering applications. A generalized humidity effect on polymer fiber diameter of the polymer solution electrospinning process was developed. The as …
Functionalization Of Peptide Nucleic Acids Via Post-Synthetic Click Chemistry, Xiaoxiao Wang
Functionalization Of Peptide Nucleic Acids Via Post-Synthetic Click Chemistry, Xiaoxiao Wang
Electronic Thesis and Dissertation Repository
Peptide Nucleic Acid (PNA) has shown great potential in molecular diagnostics, antisense/antigene therapy and nanotechnology. Like other synthetic nucleic acids and artificial analogues, PNA has been extensively modified to achieve better performance in these applications. To efficiently develop PNA probes for molecular diagnosis, this thesis is focused on versatile functionalization of PNA via post-synthetic click chemistry.
Chapter 2 presents the synthesis of quencher-free PNA molecular beacons (MBs) targeting a cystic fibrosis transmembrane conductance regulator (CFTR) sequence mutation. To avoid the tedious synthesis of functionalized PNA monomers for probe development, a simple approach to modify PNA oligomers by post-synthetic on-resin click …
Therapeutic Application Of Carbon Monoxide In Acute Limb Compartment Syndrome, Aurelia Bihari
Therapeutic Application Of Carbon Monoxide In Acute Limb Compartment Syndrome, Aurelia Bihari
Electronic Thesis and Dissertation Repository
Acute limb compartment syndrome (CS), a devastating complication of musculoskeletal trauma, develops in response to elevation of the pressure within a closed osseofascial compartment, producing muscle- and limb-threatening ischemia. Full decompression of all involved compartments by fasciotomy is the current gold-standard therapy, but it must be performed within a surgical window of 6-8 hours, before tissue damage becomes permanent.
Carbon monoxide (CO), a byproduct of heme metabolism, has been shown protective in ischemia. While inhalation of CO leads to elevation of carboxyhemoglobin (COHb), recent development of transitional metal carbonyls, CO-releasing molecules (CO-RMs), particularly the water-soluble CORM-3, delivers CO in a …