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Antibiotics And The Wasting Disease In Neonatally Thymectomized Rats, Douglas M. Grignon
Antibiotics And The Wasting Disease In Neonatally Thymectomized Rats, Douglas M. Grignon
Loma Linda University Electronic Theses, Dissertations & Projects
The administration of the antibiotic, Chloramphenicol, to pregnant rats just prior to, and for four days after delivery, diminishes the incidence of the so-called "Wasting Disease" in neonatally thymectomized rats.
A total of 50 rats were divided into the following groups:
- Thymectomy only---nonmedicated 17 rats
- Thymectomy only---medicated 12 rats
- Thymectomy-adrenalectomy---nonmedicated 5 rats
- Thymectomy-adrenalectomy---medicated 8 rats
- Controls---nonmedicated 4 rats
- Controls---medicated 4 rats
Chloramphenicol was administered in the drinking water to the mothers of groups 2, 4 and 6 for about 2 days prior to delivery and 4 days after. On the day of birth or within three days after birth, the …