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Full-Text Articles in Chemicals and Drugs
Sex Differences In Mood And Anxiety-Related Outcomes In Response To Adolescent Nicotine Exposure, Tsun Hay Jason Ng
Sex Differences In Mood And Anxiety-Related Outcomes In Response To Adolescent Nicotine Exposure, Tsun Hay Jason Ng
Electronic Thesis and Dissertation Repository
Nicotine dependence is causally linked to increased risk of mood/anxiety disorders in later life. Females are reported to experience a higher prevalence of anxiety/depressive disorders and challenges in smoking cessation therapies, suggesting a potential sex-specific response to nicotine exposure and mood/anxiety disorder risk. However, pre-clinical evidence of sex-specific responses to adolescent nicotine exposure is unclear. Thus, to determine any sex differences in anxiety/depressive-related outcomes, adolescent male and female Sprague Dawley rats received nicotine (0.4 mg/kg; 3x daily) or saline injections for 10 consecutive days, followed by behavioural testing, in-vivo electrophysiology and Western Blot analyses. Our results revealed that adolescent nicotine …
Nicotine And E-Cigarette Effect On Maximal Metabolic Rate (Mmr) In Procambarus Clarkii, Nathan Cuttica
Nicotine And E-Cigarette Effect On Maximal Metabolic Rate (Mmr) In Procambarus Clarkii, Nathan Cuttica
Williams Honors College, Honors Research Projects
The use of electronic cigarettes, commonly referred to as e-cigarettes or vapes, has increased exponentially in recent years despite the lack of research into potentially negative physiological effects. The rise in e-cigarette use is likely due to the overwhelming evidence regarding the addictive properties of nicotine and the damage caused by traditional tobacco cigarettes. Most e-cigarettes, however, still contain nicotine and are associated with a rise in nicotine-related intoxications (Belkoniene et al., 2019). There are nicotine-free e-cigarette options, which are gaining popularity, but it is unknown if they carry similar or other negative physiological effects. Studies involving e-cigarettes containing nicotine …