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The Impact Of Polybrominated Diphenyl Ether (Bde-47) Administration In Mice And Its Implications In Non-Alcoholic Fatty Liver Disease, Kristen Ciampi
The Impact Of Polybrominated Diphenyl Ether (Bde-47) Administration In Mice And Its Implications In Non-Alcoholic Fatty Liver Disease, Kristen Ciampi
Senior Honors Projects
Non-alcoholic fatty liver disease (NAFLD) is a disease characterized by the accumulation of fat in liver cells that is not due to alcohol consumption. Steatosis results when more than 5-10% of the liver’s weight consists of fat. People who are overweight, or who have diabetes or high cholesterol are more likely to develop NAFLD. Over time, NAFLD can advance to cause cirrhosis, and eventually, liver cancer or failure.
Polybrominated diphenyl ethers (PBDEs, BDEs) are brominated flame- retardants, and are found in many plastics and household products such as cars, textiles, televisions, and computers. BDEs are released into the environment and …
Evaluation Of Bde-47 And -99 Lipid Modulating Effects In Hepg2 Human Carcinoma Cells, Eileen A. Holovac
Evaluation Of Bde-47 And -99 Lipid Modulating Effects In Hepg2 Human Carcinoma Cells, Eileen A. Holovac
Senior Honors Projects
Non-alcoholic fatty liver disease (NAFLD) is becoming a significantly more common problem in today’s society, affecting up to 25% of people in the United States as reported by the American Liver Foundation. According to the American Association of the Study of Liver Diseases, NAFLD is the buildup of fat in the liver that is not caused by secondary factors such as alcohol consumption, hereditary disorders, or the use of steatogenic medication such as amioderone. A liver is considered fatty when 5-10% of the liver’s weight is fat. The progression of NAFLD can lead to cirrhosis, liver cancer, or liver failure. …