Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Acute repetitive seizure (1)
- Antineoplastic agent (1)
- Article (1)
- Autologous stem cell transplantation (1)
- Benzodiazepine (1)
-
- Blood brain barrier (1)
- Bone marrow cell (1)
- Cancer cell culture (1)
- Cancer radiotherapy (1)
- Cancer stem cell (1)
- Cancer survival (1)
- Carboplatin (1)
- Cell based gene therapy (1)
- Cell differentiation (1)
- Cell migration (1)
- Cell population (1)
- Child care (1)
- Clinical effectiveness (1)
- Clinical protocol (1)
- Clinical trial (1)
- Culture medium (1)
- Department of Cancer Biology (1)
- Drug megadose (1)
- Drug penetration (1)
- Etoposide (1)
- Evening dosage (1)
- Febrile neutropenia (1)
- Gene delivery system (1)
- Glioblastoma (1)
- Glioma (1)
Articles 1 - 2 of 2
Full-Text Articles in Chemicals and Drugs
Analyses Of Patients Who Self-Administered Diazepam Nasal Spray For Acute Treatment Of Seizure Clusters, Sunita Misra, Michael R Sperling, Vikram Rao, Jurriaan Peters, Patricia Penovich, James Wheless, R. Edward Hogan, Charles Davis, Enrique Carrazana, Adrian Rabinowicz
Analyses Of Patients Who Self-Administered Diazepam Nasal Spray For Acute Treatment Of Seizure Clusters, Sunita Misra, Michael R Sperling, Vikram Rao, Jurriaan Peters, Patricia Penovich, James Wheless, R. Edward Hogan, Charles Davis, Enrique Carrazana, Adrian Rabinowicz
Department of Medicine Faculty Papers
For acute treatment of seizure clusters in patients with epilepsy, intranasal administration of acute seizure therapies has been shown to provide accessibility and ease of use to care partners as well as the potential for self-administration by patients. Diazepam nasal spray (Valtoco®) was approved by the US Food and Drug Administration for acute treatment of intermittent, stereotypic episodes of frequent seizure activity (ie, seizure clusters, acute repetitive seizures) in patients with epilepsy aged ≥6 years. Self-administration consistent with the prescribing information is feasible and was reported by a subgroup of patients (n = 27 of 163) in a long-term phase …
A Novel And Generalizable Organotypic Slice Platform To Evaluate Stem Cell Potential For Targeting Pediatric Brain Tumors., Shengwen Calvin Li, William Gunter Loudon
A Novel And Generalizable Organotypic Slice Platform To Evaluate Stem Cell Potential For Targeting Pediatric Brain Tumors., Shengwen Calvin Li, William Gunter Loudon
Department of Cancer Biology Faculty Papers
Brain tumors are now the leading cause of cancer-related deaths in children under age 15. Malignant gliomas are, for all practical purposes, incurable and new therapeutic approaches are desperately needed. One emerging strategy is to use the tumor tracking capacity inherent in many stem cell populations to deliver therapeutic agents to the brain cancer cells. Current limitations of the stem cell therapy strategy include that stem cells are treated as a single entity and lack of uniform technology is adopted for selection of clinically relevant sub-populations of stem cells. Specifically, therapeutic success relies on the selection of a clinically competent …